Most vulnerable still needs protection from Covid despite being fully vaccinated

Description

In an analysis of recent vaccine surveillance data from Public Health England, it is noted that 97% of fully vaccinated individuals who died were aged 50 or older. Prior to the vaccine rollout in the UK, 98% of COVID-19-associated deaths were also in individuals aged 50 or above. 

The most vulnerable (elderly and immunocompromised population) is still at the most risk of severe coronavirus disease and death despite vaccination, and that this group still needs protection. It is recommended that public health authorities should look beyond vaccines to protect the most vulnerable in society, citing therapies such as antiviral drugs or monoclonal antibodies (mAbs) to be considered within 24 hours of catching the virus in all high-risk individuals, regardless of vaccination status.

It is suggested that doctors consider giving mAbs to all high-risk populations as a form of passive immunization. On Sept. 16, the U.S. FDA expanded its EUA for a duo of mAbs, bamlanivimab and etesevimab, to include post-exposure prophylaxis in certain high-risk groups.

Subject

Covid-19 and immunocompromised, booster doses, protection against hospitalization and severe disease.