Researchers develop a device that simulates gastrointestinal tract

  • Hamid Merchant

Press/Media: Research

Description

Dr Hamid Merchant have developed a novel in-vitro solution for assessment of pharmaceutical and nutraceutical products in physiologically relevant conditions. He developed innovative strategies for exploiting physiological bicarbonate buffers for dissolution testing and devised an Auto pH SystemTM – robust instrumentation and dynamic dissolution media employing physiological bicarbonate buffers simulating the aboral changes in gastrointestinal pH while dosage form transits down the gut.

Dr Merchant won a proof of concept award from the UCL Business in 2012 to further the technology and patent is already granted in UK (GB2509286B) and US (US10234467B2).

Period28 Mar 2014 → 3 Apr 2014

Media coverage

11

Media coverage

  • TitleHuddersfield University lecturer Dr Hamid Merchant develops pioneering research device
    Degree of recognitionInternational
    Media name/outletHuddersfield Examiner
    Media typeWeb
    Country/TerritoryUnited Kingdom
    Date3/04/14
    DescriptionA breakthrough in drug testing developed by a University of Huddersfield lecturer could lead to cheaper, more effective medicines.
    URLhttps://www.examinerlive.co.uk/news/west-yorkshire-news/huddersfield-university-lecturer-dr-hamid-6908291
    PersonsHamid Merchant
  • TitleDevice simulating gastrointestinal tract boon for cheaper drugs
    Degree of recognitionInternational
    Media name/outletBusiness Standard
    Media typeWeb
    Country/TerritoryUnited Kingdom
    Date1/04/14
    DescriptionIn a breakthrough, researchers have developed a device that accurately simulates gastrointestinal tract and how it absorbs medication.
    URLhttps://www.business-standard.com/article/news-ians/device-simulating-gastrointestinal-tract-boon-for-cheaper-drugs-114040100294_1.html
    PersonsHamid Merchant
  • TitleDevice simulating gastrointestinal tract boon for cheaper drugs
    Degree of recognitionInternational
    Media name/outletTopNews.IN
    Media typeWeb
    Country/TerritoryIndia
    Date1/04/14
    DescriptionIn a breakthrough, researchers have developed a device that accurately simulates gastrointestinal tract and how it absorbs medication.
    URLhttps://topnews.in/health/device-simulating-gastrointestinal-tract-boon-cheaper-drugs-219323
    PersonsHamid Merchant
  • TitleNew System Simulates Human Gut to Test Medication Absorption
    Degree of recognitionInternational
    Media name/outletMed Gadget
    Media typeWeb
    Country/TerritoryUnited Kingdom
    Date1/04/14
    DescriptionWhile new technologies coming out daily make us feel like we’re living in the future, some methods still used in the clinical and biomedical research fields we can’t wait to be replaced by less draconian means. One such issue is testing of how drugs are absorbed by body’s gastrointestinal system, which currently involves using unwilling live animals and then willing human patients in very expensive and time consuming pre-clinical and clinical trials. A new device developed at University of Huddersfield in England replicates some aspects of the human gut in order to simulate how a proposed medication will absorb into the body.
    URLhttps://www.medgadget.com/2014/04/new-system-simulates-human-gut-to-test-medication-absorption.html
    PersonsHamid Merchant
  • TitleDevice simulating gastrointestinal tract boon for cheaper drugs
    Degree of recognitionInternational
    Media name/outletZee News
    Media typeWeb
    Country/TerritoryIndia
    Date1/04/14
    DescriptionIn a breakthrough, researchers have developed a device that accurately simulates gastrointestinal tract and how it absorbs medication. The discovery could lead to cheaper, more effective medicines.
    URLhttps://zeenews.india.com/news/health/health-news/device-simulating-gastrointestinal-tract-boon-for-cheaper-drugs_27373.html
    PersonsHamid Merchant
  • TitleIntestinal breakthrough
    Degree of recognitionInternational
    Media name/outletThe Jupital
    Media typeWeb
    Country/TerritoryUnited Kingdom
    Date1/04/14
    DescriptionResearchers have created a device that simulates the human gastrointestinal tract, meaning costly animal trials could be a thing of the past.
    URLhttps://thejupital.com/intestinal-breakthrough/
    PersonsHamid Merchant
  • TitleGut simulator could bring down the costs of drug development
    Degree of recognitionInternational
    Media name/outletNew Atlas
    Media typeWeb
    Country/TerritoryUnited Kingdom
    Date1/04/14
    DescriptionBefore drugs are tested on humans, they first go through pre-clinical tests on animals. Because humans and animals don't have identical gastrointestinal tracts, however, the way in which the drugs are absorbed by the body often differs between the two. A scientist from the UK's University of Huddersfield hopes to address that discrepancy, with his "gut simulator."
    URLhttps://newatlas.com/gut-simulator-drug-testing/31454/
    PersonsHamid Merchant
  • TitleNew device that simulates the human gut will save money and reduce testing on animals
    Degree of recognitionInternational
    Media name/outletMedical Xpress
    Media typeWeb
    Country/TerritoryUnited Kingdom
    Date31/03/14
    DescriptionA breakthrough in drug testing developed by a University of Huddersfield lecturer could lead to cheaper, more effective medicines. Dr Hamid Merchant is a member of the team that has created a device which accurately simulates the gastrointestinal tract and how it absorbs medication. This means that the cost of clinical trials could be greatly reduced, with savings passed on to customers.
    URLhttps://medicalxpress.com/news/2014-03-device-simulates-human-gut-money.html
    PersonsHamid Merchant
  • TitleResearchers develop device that simulates gastro-intestinal tract
    Degree of recognitionInternational
    Media name/outletPress-News
    Media typeWeb
    Country/TerritoryUnited Kingdom
    Date31/03/14
    DescriptionA breakthrough in drug testing developed by a University of Huddersfield lecturer could lead to cheaper, more effective medicines. Dr Hamid Merchant is a member of the team that has created a device which accurately simulates the gastro-intestinal tract and how it absorbs medication. This means that the cost of clinical trials could be greatly reduced, with savings passed on to customers.
    URLhttps://press-news.org/126700-researchers-develop-device-that-simulates-gastro-intestinal-tract.html
    PersonsHamid Merchant
  • TitleNew device simulating human gut will save money, reduce testing on animals
    Degree of recognitionInternational
    Media name/outletScience Daily
    Media typeWeb
    Country/TerritoryUnited Kingdom
    Date28/03/14
    Description breakthrough in drug testing could lead to cheaper, more effective medicines. A device has been created that accurately simulates the gastro-intestinal tract and how it absorbs medication. This means that the cost of clinical trials, as well as the use of animals in testing, could be greatly reduced, with savings passed on to customers.
    URLhttps://www.sciencedaily.com/releases/2014/03/140328175131.htm
    PersonsHamid Merchant
  • TitleResearchers develop device that simulates gastro-intestinal tract
    Degree of recognitionLocal
    Media name/outletHuddersfield University News
    Media typeWeb
    Country/TerritoryUnited Kingdom
    Date28/03/14
    DescriptionA BREAKTHROUGH in drug testing developed by a University of Huddersfield lecturer could lead to cheaper, more effective medicines. Dr Hamid Merchant is a member of the team that has created a device which accurately simulates the gastro-intestinal tract and how it absorbs medication. This means that the cost of clinical trials could be greatly reduced, with savings passed on to customers.
    URLhttps://news-archive.hud.ac.uk/news/2014/march/researchersdevelopdevicethatsimulatesgastro-intestinaltract.php
    PersonsHamid Merchant