Cellular and Molecular Models of Disease Centre

  • United Kingdom

Organization profile

Profile Information

Our understanding of biological processes involved in normal tissue development and disease has resulted in the development of a wide range of experimental models that increasingly reflect the complexity of biological systems. The focus of this research centre is to develop and apply these experimental models to address key questions in the biology of normal tissues and disease. An additional focus of this research centre is the development of alternatives to animal models in line with the principles of reduction, replacement and refinement (the 3Rs). The centres activities include:

  • Dermatogenetics – genetic skin disease
  • Hair growth and hair loss including chemotherapy induced alopecia
  • DNA damage response and genomic integrity in cancer
  • Metabolic physiology and ageing related disease
  • Lyme’s disease
  • Regulation of cellular development and metabolism

Fingerprint Dive into the research topics where Cellular and Molecular Models of Disease Centre is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.

Hair Follicle Medicine & Life Sciences
Dupuytren Contracture Medicine & Life Sciences
Alopecia Medicine & Life Sciences
Oxidative stress Chemical Compounds
Trypanosomiasis Medicine & Life Sciences
Basal Bodies Medicine & Life Sciences
Genome-Wide Association Study Medicine & Life Sciences
Scalp Medicine & Life Sciences

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Research Output 2014 2019

Confocal microscopy
Image resolution
Confocal Microscopy

A Centriolar FGR1 Oncogene Partner-Like Protein Required for Paraflagellar Rod Assembly, But Not Axoneme Assembly in African Trypanosomes: Trypanosome FOPL function

Harmer, J., Towers, K., Addison, M., Vaughan, S., Ginger, M. L. & McKean, P. G., 1 Jul 2018, In : Open Biology. 8, 7, 13 p., 170218.

Research output: Contribution to journalArticle

Open Access
Microtubule-Organizing Center
7 Citations (Scopus)

A Clinical and Biological Guide for Understanding Chemotherapy-Induced Alopecia and Its Prevention

Dunnill, C., Al Tameemi, W., Collett, A., Haslam, I. & Georgopoulos, N., Jan 2018, In : Oncologist. 23, 1, p. 84-96 13 p.

Research output: Contribution to journalReview article

Open Access
Drug Therapy
Hair Follicle

Projects 2015 2017

Activities 2001 2019

PhD External Examiner at the Universit Putra Malaysia

Roger Phillips (Examiner)
19 Nov 2019

Activity: Examination typesPhD Examination

The preclinical and clinical development of Apaziquone - the trials and tribulations of working in drug development

Roger Phillips (Keynote speaker)
23 Oct 201925 Oct 2019

Activity: Talk or presentation typesInvited talk

PhD External Examination at the University of Leeds

Roger Phillips (Examiner)
14 Oct 2019

Activity: Examination typesPhD Examination