Cellular and Molecular Models of Disease Centre

  • United Kingdom

Organization profile

Profile Information

Our understanding of biological processes involved in normal tissue development and disease has resulted in the development of a wide range of experimental models that increasingly reflect the complexity of biological systems. The focus of this research centre is to develop and apply these experimental models to address key questions in the biology of normal tissues and disease. An additional focus of this research centre is the development of alternatives to animal models in line with the principles of reduction, replacement and refinement (the 3Rs). The centres activities include:

  • Dermatogenetics – genetic skin disease
  • Hair growth and hair loss including chemotherapy induced alopecia
  • DNA damage response and genomic integrity in cancer
  • Metabolic physiology and ageing related disease
  • Lyme’s disease
  • Regulation of cellular development and metabolism

Fingerprint Dive into the research topics where Cellular and Molecular Models of Disease Centre is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.

Hair Follicle Medicine & Life Sciences
Dupuytren Contracture Medicine & Life Sciences
Alopecia Medicine & Life Sciences
Oxidative stress Chemical Compounds
Genome-Wide Association Study Medicine & Life Sciences
Scalp Medicine & Life Sciences
Hair Medicine & Life Sciences
Mutation Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2014 2018

6 Citations (Scopus)

A Clinical and Biological Guide for Understanding Chemotherapy-Induced Alopecia and Its Prevention

Dunnill, C., Al Tameemi, W., Collett, A., Haslam, I. & Georgopoulos, N., Jan 2018, In : Oncologist. 23, 1, p. 84-96 13 p.

Research output: Contribution to journalReview article

Open Access
Alopecia
Scalp
Drug Therapy
Hair Follicle
Psychology

A Life-Line for the Pedagogic Goose: Harnessing the Graduate Perspective in Arts Education

Tinker, A., Greenhough, K. & Caldwell, E., 26 Nov 2018, In : Arts. 7, 4, 12 p., 88.

Research output: Contribution to journalArticle

Open Access
art education
pedagogics
assistant
graduate
tutor
2 Citations (Scopus)

Farming, slaving and enslavement: Histories of endosymbioses during kinetoplastid evolution

Harmer, J., Yurchenko, V., Nenarokova, A., Lukeš, J. & Ginger, M., 1 Sep 2018, In : Parasitology. 145, 10, p. 1311-1323 13 p.

Research output: Contribution to journalArticle

Open Access
File
Slavery
Trypanosomatidae
Symbiosis
Agriculture
symbiosis

Projects 2015 2017

C. elegans model to unravel the role of Klotho in ion metabolism and aging

Kinnunen, T.

1/01/1531/12/17

Project: ResearchResearch Council - Other

Activities 2001 2019

The preclinical and clinical development of Apaziquone - the trials and tribulations of working in drug development

Roger Phillips (Keynote speaker)
23 Oct 201925 Oct 2019

Activity: Talk or presentation typesInvited talk

PhD External Examination at the University of Leeds

Roger Phillips (Examiner)
14 Oct 2019

Activity: Examination typesPhD Examination

Targeting the hypoxic fraction of cancer

Roger Phillips (Speaker)
10 Oct 2019

Activity: Talk or presentation typesInvited talk

File