Organisation profile
Organisation profile
Our understanding of biological processes involved in normal tissue development and disease has resulted in the development of a wide range of experimental models that increasingly reflect the complexity of biological systems. The focus of this research centre is to develop and apply these experimental models to address key questions in the biology of normal tissues and disease. An additional focus of this research centre is the development of alternatives to animal models in line with the principles of reduction, replacement and refinement (the 3Rs). The centres activities include:
- Dermatogenetics – genetic skin disease
- Hair growth and hair loss including chemotherapy induced alopecia
- DNA damage response and genomic integrity in cancer
- Metabolic physiology and ageing related disease
- Lyme’s disease
- Regulation of cellular development and metabolism
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
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SDG 2 Zero Hunger -
SDG 3 Good Health and Well-being -
SDG 4 Quality Education -
SDG 9 Industry, Innovation, and Infrastructure -
SDG 10 Reduced Inequalities -
SDG 12 Responsible Consumption and Production -
SDG 14 Life Below Water
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Collaborations and top research areas from the last five years
Profiles
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Simon Allison
- Department of Physical and Life Sciences - Reader
- School of Applied Sciences
- Pharmacology and Therapeutics Centre - Member
- Cellular and Molecular Models of Disease Centre - Associate Membership
Person: Academic
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Richard Bingham
- Department of Physical and Life Sciences - Senior Lecturer - Biomedical & Life Sciences
- School of Applied Sciences
- Cellular and Molecular Models of Disease Centre - Member
- Biopolymer Research Centre - Member
Person: Academic
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Anke Bruning-Richardson
- Department of Physical and Life Sciences - Senior Lecturer in Biomedicine / Pharmacology
- School of Applied Sciences
- Centre for Biomarker Research - Member
- Cellular and Molecular Models of Disease Centre - Associate Member
- Pharmacology and Therapeutics Centre - Associate Member
Person: Academic
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Beyond the pandemic: Natural products against coronavirus cytokine storm
Olajide, O., 5 Mar 2026, In: Planta Medica. 92, 3, 1 p., 251.Research output: Contribution to journal › Meeting Abstract › peer-review
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Borrelia BBJ25 is a plasmid-encoded Omp85-family protein associated with a potential export system
Nixon, A., Soliman, E., Bryk, J., Carr, M., Cooper, C. D. O. & Bingham, R. J., 6 Feb 2026, In: Bioscience Reports. 46, 2, 12 p., BSR20254082.Research output: Contribution to journal › Article › peer-review
Open Access -
Comparative onset of PGE2/COX-2 reduction by flurbiprofen and benzydamine in human bronchialepithelial (BEAS-2B) cells stimulated with polyinosinic:polycytidylic acid (poly I:C)
Mfotie Njoya, E., Spears, M., Hallett, T. & Olajide, O., 1 Feb 2026, In: British Journal of Pharmacology. 183, 3, 1 p., 290.Research output: Contribution to journal › Meeting Abstract › peer-review
Open Access
Projects
- 4 Finished
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C. elegans model to unravel the role of Klotho in ion metabolism and aging
Kinnunen, T. (PI)
1/01/15 → 31/12/17
Project: Research
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Centre for Biominetic Societal Futures
Towns-Andrews, L. (PI), Kusev, P. (CoI), Kara, A. (CoI), Herath, D. (CoI), Validi, S. (CoI), Jabbar, A. (CoI), Nikitas, A. (CoI), Roper, S. (CoI), Ginger, M. (CoI), Phillips, R. (CoI), Du, C. (CoI), Amaratunga, D. (CoI), Haigh, R. (CoI), Murphy, A. (CoI), Hill, R. (CoI), Parkinson, S. (CoI), Johnson, A. (CoI), Bryan, H. (CoI), Thomas, P. (CoI), McIntyre, D. (CoI), Jeffries, L. (CoI), Bailey, R. (CoI), Townsley, J. (CoI), Unver, E. (CoI), Goswami, P. (CoI), Roach, J. (CoI), Grimm, V. (CoI), Worley, C. (CoI), Siebers, P.-O. (CoI), Bardone, E. (CoI), Madsen, J. K. (CoI), Neumann, M. (CoI), Seri, R. (CoI), Durrant, R. (CoI), Wortley, R. (CoI), Sidebottom, A. (CoI), Ekblom, P. (CoI), Pease, K. (CoI), Taylor, M. (CoI), Silke, A. (CoI), Dewandre, N. (CoI) & Hemachandra, K. (CoI)
1/10/21 → 30/09/24
Project: Research
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Pre-clinical ‘de-risking’ of self-assembling cryptate compounds as putative anti-cancer agents
Allison, S. (PI)
10/02/23 → 30/06/24
Project: Research
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Natural selection and mutation pressure, upon both mRNA and tRNA genes, determine codon bias in Trichomonas vaginalis
Carr, M. (Speaker)
7 Jan 2026Activity: Talk or presentation types › Oral presentation
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PhD viva at Brown University on FTO as potential target in GBM
Bruning-Richardson, A. (Examiner)
5 Jan 2026Activity: Examination types › PhD Examination
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Targeting of Inflammatory Signalling Pathways by Natural Products from African Plants
Olajide, O. (Speaker)
28 Nov 2025Activity: Talk or presentation types › Oral presentation
Press/Media
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YBTC teams up with Huddersfield Uni
20/03/23
1 item of Media coverage
Press/Media: Public Engagement Activities