Research Output 2011 2019

2019

Discovery of selective, antimetastatic and anti-cancer stem cell metallohelices via post-assembly modification

Song, H., Rogers, N., Allison, S. J., Brabec, V., Bridgewater, H., Kostrhunova, H., Markova, L., Phillips, R., Pinder, E., Shepherd, S., Young, L., Zajac, J. & Scott, P., 18 Jul 2019, In : Chemical Science. 11 p.

Research output: Contribution to journalArticle

Open Access
Stem cells
Pharmaceutical Preparations
Ouabain
Self assembly
Adenosine Triphosphatases
5 Citations (Scopus)

Evolution of a maternal immune activation (mIA) model in rats: Early developmental effects

Murray, K. N., Edye, M. E., Manca, M., Vernon, A. C., Oladipo, J. M., Fasolino, V., Harte, M. K., Mason, V., Grayson, B., McHugh, P. C., Knuesel, I., Prinssen, E. P., Hager, R. & Neill, J. C., Jan 2019, In : Brain, Behavior, and Immunity. 75, p. 48-59 12 p.

Research output: Contribution to journalArticle

Open Access
File
Mothers
Poly I-C
Wistar Rats
Interleukin-6
Injections
File
Pharmacy Students
Prescriptions
Learning
Safety
Education
Open Access
File
apaziquone
Phase III Clinical Trials
Hematuria
Urinary Bladder Neoplasms
Blood

Repurposing of Tranilast for Potential Neuropathic Pain Treatment by Inhibition of Sepiapterin Reductase in the BH4 Pathway

Moore, B. J. R., Islam, B., Ward, S., Jackson, O., Armitage, R., Blackburn, J., Haider, S. & Mchugh, P. C., 31 Jul 2019, In : ACS Omega. 4, 7, p. 11960-11972 13 p.

Research output: Contribution to journalArticle

Open Access
sepiapterin reductase
Molecules
Production control
Nitric oxide
Spectrophotometry
2018
1 Citation (Scopus)

Increased Oxidative Stress as a Risk Factor in Chronic Idiopathic Axonal Polyneuropathy

Zis, P., Mchugh, P. C., Manca, M., Sarrigiannis, P. G., Rao, D. G. & Hadjivassiliou, M., Dec 2018, In : Journal of Molecular Neuroscience. 66, 4, p. 547-551 5 p.

Research output: Contribution to journalArticle

Open Access
Polyneuropathies
Oxidative Stress
Glutens
Proteins
Demography

MicroRNA quantitation during dendritic cell endocytosis using Imaging Flow Cytometry: key factors and requirements

Tong, Q., Zhu, Y., Zhang, D., Cai, Q., Qu, W., Cooper, C., Wang, J. & McHugh, P., 21 Nov 2018, In : Cellular Physiology and Biochemistry. 51, 2, p. 793-811 19 p., 2018MS533.

Research output: Contribution to journalArticle

Open Access
Flow cytometry
Endocytosis
MicroRNAs
Dendritic Cells
Flow Cytometry

Nonsynonymous Polymorphism in Guanine Monophosphate Synthetase Is a Risk Factor for Unfavorable Thiopurine Metabolite Ratios in Patients With Inflammatory Bowel Disease

Roberts, R. L., Wallace, M. C., Seinen, M. L., Van Bodegraven, A. A., Krishnaprasad, K., Jones, G. T., Van Rij, A. M., Baird, A., Lawrance, I. C., Prosser, R., Bampton, P., Grafton, R., Simms, L. A., Studd, C., Bell, S. J., Kennedy, M. A., Halliwell, J., Gearry, R. B., Radford-smith, G., Andrews, J. M. & 2 othersMchugh, P. C. & Barclay, M. L., Dec 2018, In : Inflammatory Bowel Diseases. 24, 12, p. 2606-2612 7 p.

Research output: Contribution to journalArticle

Open Access
File
Guanine
Ligases
Inflammatory Bowel Diseases
Single Nucleotide Polymorphism
Exome
Bandages
Mental Competency
Nurses
Education
Tissue Survival
2 Citations (Scopus)

The Development of Translational Biomarkers as a Tool for Improving the Understanding, Diagnosis and Treatment of Chronic Neuropathic Pain

Buckley, D. A., Jennings, E. M., Burke, N. N., Roche, M., McInerney, V., Wren, J. D., Finn, D. P. & McHugh, P. C., 1 Mar 2018, In : Molecular Neurobiology. 55, 3, p. 2420-2430 11 p.

Research output: Contribution to journalArticle

Open Access
Neuralgia
Matrix Metalloproteinase 1
Tissue Inhibitor of Metalloproteinase-1
Chronic Pain
Biomarkers
2 Citations (Scopus)

The Regulation of Monoamine Oxidase A Gene Expression by Distinct Variable Number Tandem Repeats

Manca, M., Pessoa, V., Lopez, A. I., Harrison, P. T., Miyajima, F., Sharp, H., Pickles, A., Hill, J., Murgatroyd, C., Bubb, V. J. & Quinn, J. P., Mar 2018, In : Journal of Molecular Neuroscience. 64, 3, p. 459-470 12 p.

Research output: Contribution to journalArticle

Open Access
Minisatellite Repeats
Monoamine Oxidase
Gene Expression
Protein Isoforms
Haplotypes
2017
7 Citations (Scopus)

Cognitive ability in Down syndrome and its relationship to urinary neopterin, a marker of activated cellular immunity

Zis, P., Strydom, A., Buckley, D., Adekitan, D. & Mchugh, P. C., 1 Jan 2017, In : Neuroscience Letters. 636, p. 254-257

Research output: Contribution to journalArticle

Neopterin
Aptitude
Down Syndrome
Cellular Immunity
Vocabulary
2011
2 Citations (Scopus)

Identification of depressive disorder among older people in care homes - a feasibility study.

Morrell, C. J., Curran, S., Topping, A., Shaik, K., Muthukrishnan, V. & Stephenson, J., Jul 2011, In : Primary health care research & development. 12, 3, p. 255-265 11 p.

Research output: Contribution to journalArticle

Feasibility Studies
Home Care Services
Depressive Disorder
Depression
Geriatrics