Institute of Molecular Medicine

Organization profile

Profile Information

Research fields in the Molecular Medicine Research Group include Dr Nik Georgopoulos's work on the molecular basis of epithelial cell cancer development, Dr Richard Bingham's work on the structural basis of pathogenicity of bacteria, Dr Georgios Pskais's structural and functional characterisation of ion channels, Dr Andrew Collett's investigation of intestinal inflammation, Dr Peter Maskell's studies of the post-mortem redistribution of drugs, Dr Tarja Kinnunen's research into growth factor signalling and Dougie Clarke's work on the molecular biology of drug metabolising enzymes. 

 

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Ligands Chemical Compounds
Ruthenium Chemical Compounds
Cells Chemical Compounds
apaziquone Chemical Compounds
Coordination Complexes Chemical Compounds
Cytotoxicity Chemical Compounds
Iridium Chemical Compounds
Rhodium Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2017 2019

Cellular uptake and efflux of palbociclib in vitro in single cell and spheroid models s

Jove, M., Spencer, J. A., Hubbard, M. E., Holden, E. C., O'dea, R. D., Brook, B. S., Phillips, R. M., Smye, S. W., Loadman, P. & Twelves, C. J., 1 Aug 2019, In : Journal of Pharmacology and Experimental Therapeutics. 370, 2, p. 242-251 10 p.

Research output: Contribution to journalArticle

Open Access
File
Suspensions
Pharmaceutical Preparations
MCF-7 Cells
Neoplasms
Cyclin-Dependent Kinase 6
1 Citation (Scopus)

Discovery of selective, antimetastatic and anti-cancer stem cell metallohelices via post-assembly modification

Song, H., Rogers, N., Allison, S. J., Brabec, V., Bridgewater, H., Kostrhunova, H., Markova, L., Phillips, R., Pinder, E., Shepherd, S., Young, L., Zajac, J. & Scott, P., 2019, In : Chemical Science. 10, 37, p. 8547-8557 11 p.

Research output: Contribution to journalArticle

Open Access
Stem cells
Pharmaceutical Preparations
Ouabain
Self assembly
Adenosine Triphosphatases
Open Access
File
apaziquone
Phase III Clinical Trials
Hematuria
Urinary Bladder Neoplasms
Blood

Activities 2001 2019

PhD External Examiner at the Universit Putra Malaysia

Roger Phillips (Examiner)
19 Nov 2019

Activity: Examination typesPhD Examination

The preclinical and clinical development of Apaziquone - the trials and tribulations of working in drug development

Roger Phillips (Keynote speaker)
23 Oct 201925 Oct 2019

Activity: Talk or presentation typesInvited talk

PhD External Examination at the University of Leeds

Roger Phillips (Examiner)
14 Oct 2019

Activity: Examination typesPhD Examination