Pharmaceutics and Drug Delivery Centre

Research Output 2014 2019

Filter
Article
2019
1 Citation (Scopus)

Characterizing Drug-Polymer Bead Interactions Using Isothermal Titration Calorimetry

Swaine, T., Garcia, P., Tang, Y., Lewis, A., Parkes, G. & Waters, L., 1 May 2019, In : Journal of Pharmaceutical Sciences. 108, 5, p. 1772-1778 7 p.

Research output: Contribution to journalArticle

Open Access
Calorimetry
Polymers
irinotecan
Hydrogel
Doxorubicin
Open Access
Gels
Polymers
Growth
Porosity
Tablets
1 Citation (Scopus)

Effect of preparation method on the surface properties and UV imaging of indomethacin solid dispersions

Asare-Addo, K., Totea, A-M., Mawla, N., Walton, K., Taheri, S., Ward, A., Adebisi, A., Al Shafiee, M., Timmins, P. & Conway, B., 1 Apr 2019, In : European Journal of Pharmaceutics and Biopharmaceutics. 137, p. 148-163 16 p.

Research output: Contribution to journalArticle

Freeze Drying
Surface Properties
Indomethacin
Powder Diffraction
Differential Scanning Calorimetry
1 Citation (Scopus)

In-situ 3D nanoscale advanced imaging algorithms with integrated chemical imaging for the characterisation of pharmaceuticals

Nirwan, J., Conway, B. & Ghori, M. U., 1 Jun 2019, In : RSC Advances. 9, 28, p. 16119-16129 11 p.

Research output: Contribution to journalArticle

Open Access
Drug products
Swelling
Imaging techniques
Tablets
Erosion

Investigating potential wound healing properties of polysaccharides extracted from Grewia mollis Juss. and Hoheria populnea A. Cunn. (Malvaceae)

Pearman, N., Moxon, S., Carnachan, S. M., Cooke, M. E., Nep, E. I., Sims, I. M., Morris, G. & Smith, A., Oct 2019, In : Bioactive Carbohydrates and Dietary Fibre. 20, 8 p., 100201.

Research output: Contribution to journalArticle

Grewia
Malvaceae
tissue repair
Wound Healing
Polysaccharides
Open Access
Differential thermal analysis
thermal analysis
Microwaves
formulations
microwaves

Quantification of the adsorption of benzoates on poly(dimethylsiloxane) membrane

Waters, L., Jesney, H., Molinari, M. & Shahzad, Y., 1 Sep 2019, In : European Polymer Journal. 118, p. 286-289 4 p.

Research output: Contribution to journalArticle

Benzoates
Polydimethylsiloxane
membranes
Membranes
Adsorption
Dry Powder Inhalers
Chronic Obstructive Pulmonary Disease
Inhalation
Capsules
Pharmaceutical Preparations
2018
3 Citations (Scopus)

Behavior of In Situ Cross-Linked Hydrogels with Rapid Gelation Kinetics on Contact with Physiological Fluids

Diryak, R., Kontogiorgos, V., Ghori, M. U., Bills, P., Tawfik, A., Morris, G. A. & Smith, A., Apr 2018, In : Macromolecular Chemistry and Physics. 219, 8, 6 p., 1700584.

Research output: Contribution to journalArticle

Open Access
File
Hydrogels
gelation
Gelation
Contacts (fluid mechanics)
Kinetics
5 Citations (Scopus)

Enhancing the dissolution of phenylbutazone using Syloid® based mesoporous silicas for oral equine applications

Waters, L. J., Hanrahan, J. P., Tobin, J. M., Finch, C. V., Parkes, G. M. B., Ahmad, S. A., Mohammad, F. & Saleem, M., Jun 2018, In : Journal of Pharmaceutical Analysis. 8, 3, p. 181-186 6 p.

Research output: Contribution to journalArticle

Open Access
Phenylbutazone
Silicon Dioxide
Horses
Dissolution
Silica
4 Citations (Scopus)

Evaluating the swelling, erosion, and compaction properties of cellulose ethers

Ghori, M. U., Grover, L. M., Asare-Addo, K., Smith, A. M. & Conway, B. R., 7 Feb 2018, In : Pharmaceutical Development and Technology. 23, 2, p. 183-197 15 p.

Research output: Contribution to journalArticle

Open Access
Ethers
Cellulose
Polymers
Porosity
Particle Size
5 Citations (Scopus)

Experimental versus theoretical log D 7.4, pK a and plasma protein binding values for benzodiazepines appearing as new psychoactive substances

Manchester, K., Maskell, P. & Waters, L., Aug 2018, In : Drug Testing and Analysis. 10, 8, p. 1258-1269 12 p.

Research output: Contribution to journalArticle

Open Access
File
Benzodiazepines
Protein Binding
Blood Proteins
plasma
protein
1 Citation (Scopus)

Hydro-Alcoholic Media Effects on Theophylline Release from Sesamum Polysaccharide Gum Matrices

Nep, E. I., Mahdi, M., Adebisi, A., Ngwuluka, N. C., Conway, B., Smith, A. & Asare-Addo, K., 1 Feb 2018, In : Drug Development and Industrial Pharmacy. 44, 2, p. 251-260 10 p.

Research output: Contribution to journalArticle

Open Access
Sesamum
Gingiva
Theophylline
Polysaccharides
Alcohols
3 Citations (Scopus)

Impact of processing methods on the dissolution of artemether from two non-ordered mesoporous silicas

Tahir, H., Shahzad, Y., Waters, L., Hussain, T., Yousaf, A., Mahmood, T. & Sheikh, R., 15 Jan 2018, In : European Journal of Pharmaceutical Sciences. 112, p. 139-145 7 p.

Research output: Contribution to journalArticle

Open Access
File
Silicon Dioxide
Freeze Drying
Solubility
Pharmaceutical Preparations
Differential Scanning Calorimetry
1 Citation (Scopus)

Incorporating physiologically relevant mobile phases in micellar liquid chromatography for the prediction of human intestinal absorption

Shokry, D., Waters, L., Parkes, G. & Mitchell, J. C., Dec 2018, In : Biomedical Chromatography. 32, 12, 9 p., e4351.

Research output: Contribution to journalArticle

Open Access
File
Intestinal Absorption
Liquid chromatography
Liquid Chromatography
Lecithins
Bile Acids and Salts
6 Citations (Scopus)

Influence of Polymer Ratio and Surfactants on Controlled Drug Release from Cellulosic Microsponges

Shahzad, Y., Saeed, S., Ghori, M., Mahmood, T., Yousaf, M., Jamshaid, M., Sheikh, R. & Rizvi, S. A. A., Apr 2018, In : International Journal of Biological Macromolecules. 109, p. 963-970 8 p.

Research output: Contribution to journalArticle

Open Access
Surface-Active Agents
Polymers
Pharmaceutical Preparations
Ketoprofen
Polyvinyl Alcohol
9 Citations (Scopus)
Open Access
File
Polysaccharides
Nuclear magnetic resonance spectroscopy
Oligosaccharides
Acids
Biopolymers
3 Citations (Scopus)

Study of the Emitted Dose After Two Separate Inhalations at Different Inhalation Flow Rates and Volumes and an Assessment of Aerodynamic Characteristics of Indacaterol Onbrez Breezhaler®150 and 300 μg

Abadelah, M., Chrystyn, H., Bagherisadeghi, G., Abdalla, G. & Larhrib, H., 1 Jan 2018, In : AAPS PharmSciTech. 19, 1, p. 251-261 11 p.

Research output: Contribution to journalArticle

Open Access
aerodynamics
Inhalation
breathing
dosage
strength (mechanics)

The effect of mesoporous silica impregnation on tribo-electrification characteristics of flurbiprofen

Afzal, M. S., Zanin, F., Ghori, M. U., Granollers, M. & Šupuk, E., 10 Jun 2018, In : International Journal of Pharmaceutics. 544, 1, p. 55-61 7 p.

Research output: Contribution to journalArticle

Open Access
File
Flurbiprofen
Silicon Dioxide
Pharmaceutical Preparations
Powders
Static Electricity
4 Citations (Scopus)

The use of a quantitative structure-activity relationship (QSAR) model to predict GABA-A receptor binding of newly emerging benzodiazepines

Waters, L., Manchester, K. R., Maskell, P. D., Haegeman, C. & Haider, S., 1 May 2018, In : Science and Justice. 58, 3, p. 219-225 7 p.

Research output: Contribution to journalArticle

Open Access
File
Quantitative Structure-Activity Relationship
GABA-A Receptors
Benzodiazepines
Pharmacology
Economics
2017

Can Diet Help Non-Obese Individuals with Non-Alcoholic Fatty Liver Disease (NAFLD)?

Merchant, H., 19 Sep 2017, In : Journal of Clinical Medicine. 6, 9, 5 p., 88.

Research output: Contribution to journalArticle

Open Access
Diet
Life Style
Body Mass Index
Incidental Findings
Liver

Chemical Imaging by Dissolution Analysis: Localized Kinetics of Dissolution Behavior to Provide Two-Dimensional Chemical Mapping and Tomographic Imaging on a Nanoscale

Reading, M., Ghori, M., Brown, D. R., Fleming, L., Antonijevic, M. D., Grandy, D. B., Hourston, D. J., Song, M. & Conway, B., 6 Jun 2017, In : Analytical Chemistry. 89, 11, p. 5882-5890 9 p.

Research output: Contribution to journalArticle

Open Access
Dissolution
Imaging techniques
Kinetics
Polymethyl Methacrylate
Surface structure
7 Citations (Scopus)

Cold atmospheric pressure plasma for treatment of chronic wounds: Drug or medical device?

Kramer, A., Conway, B. R., Meissner, K., Scholz, F., Rauch, B. H., Moroder, A., Ehlers, A., Meixner, A. J., Heidecke, C. D., Partecke, L. I., Kietzmann, M. & Assadian, O., 10 Aug 2017, In : Journal of wound care. 26, 8, p. 470-475 6 p.

Research output: Contribution to journalArticle

Open Access
Atmospheric Pressure
Equipment and Supplies
Wounds and Injuries
Pharmaceutical Preparations
Medical Economics
4 Citations (Scopus)

Crystal Packing Arrangement, Chain Conformation, and Physicochemical Properties of Gemfibrozil Amine Salts

Ramirez, M., David, S. E., Schwalbe, C. H., Asare-Addo, K., Conway, B. & Timmins, P., 13 Jun 2017, In : Crystal Growth and Design. 17, 7, p. 3743-3750 8 p.

Research output: Contribution to journalArticle

Open Access
Gemfibrozil
Amines
Conformations
amines
Salts
3 Citations (Scopus)
Open Access
Pharmacists
Cost-Benefit Analysis
Patient Safety
Management Decision Support Systems
Costs and Cost Analysis
9 Citations (Scopus)

Effect of maximum inhalation flow and inhaled volume on formoterol drug deposition in-vitro from an Easyhaler® dry powder inhaler

Abadelah, M., Hazim, F., Chrystyn, H., Bagherisadeghi, G., Rahmoune, H. & Larhrib, H., 15 Jun 2017, In : European Journal of Pharmaceutical Sciences. 104, p. 180-187 8 p.

Research output: Contribution to journalArticle

Dry Powder Inhalers
Inhalation
Pharmaceutical Preparations
Formoterol Fumarate
In Vitro Techniques
4 Citations (Scopus)

Effect of Plasma Surface Treatment of Poly(dimethylsiloxane) on the Permeation of Pharmaceutical Compounds

Waters, L., Finch, C., Bhuiyan, A., Hemming, K. & Mitchell, J., Oct 2017, In : Journal of Pharmaceutical Analysis. 7, 5, p. 338-342 5 p.

Research output: Contribution to journalArticle

Open Access
Permeation
Surface treatment
Plasmas
Pharmaceutical Preparations
Membranes
4 Citations (Scopus)

Enhanced Chlorhexidine Skin Penetration with 1,8-cineole

Casey, A. L., Karpanen, T. J., Conway, B., Worthington, T., Nightingale, P., Waters, R. & Elliott, T. S. J., 17 May 2017, In : BMC Infectious Diseases. 17, 350, 5 p.

Research output: Contribution to journalArticle

Open Access
Chlorhexidine
Skin
2-Propanol
Surgical Wound Infection
Eucalyptus

Going Natural: Using Polymers from Nature for Gastroresistant Applications

Cunha Barbosa, J., Conway, B. & Merchant, H., 5 Jul 2017, In : British Journal of Pharmacy. 2, 1, 17 p.

Research output: Contribution to journalArticle

Open Access
Dietary supplements
Natural polymers
Industrial applications
Polymers
Health
16 Citations (Scopus)

Impact of Purification on Physicochemical, Surface and Functional Properties of Okra Biopolymer

Ghori, M. U., Mohammad, M. A., Rudrangi, S. R. S., Fleming, L. T., Merchant, H., Smith, A. M. & Conway, B. R., Oct 2017, In : Food Hydrocolloids. 71, p. 311-320 10 p.

Research output: Contribution to journalArticle

Open Access
Abelmoschus
Biopolymers
okra
Surface Properties
biopolymers
7 Citations (Scopus)
Gemfibrozil
Ephrin-A5
Dispersions
Silicon Dioxide
dissolving
Open Access
silicones
Silicones
Surface-Active Agents
Permeation
Drug products
9 Citations (Scopus)
Chronic Obstructive Pulmonary Disease
Inhalation
Dry Powder Inhalers
Formoterol Fumarate Drug Combination Budesonide
Budesonide
2 Citations (Scopus)

Solid state characterization and rheological properties of native and modified Bambara groundnut (Vigna subterranean) starches

Odeniyi, M., Omoteso, O. A. & Adebisi, A. O., 23 Sep 2017, In : Journal of Excipients and Food Chemicals. 8, 3, p. 42-51 10 p.

Research output: Contribution to journalArticle

Open Access
Vigna subterranea
rheological properties
Starch
starch
Nuts
4 Citations (Scopus)

The influence of hydroalcoholic media on the performance of Grewia polysaccharide in sustained release tablets

Nep, E. I., Mahdi, M., Adebisi, A., Dawson, C., Walton, K., Bills, P., Conway, B., Smith, A. & Asare-Addo, K., 30 Oct 2017, In : International Journal of Pharmaceutics. 532, 1, p. 352-364 13 p.

Research output: Contribution to journalArticle

Open Access
Grewia
Tablets
Polysaccharides
Alcohols
Ethanol
2 Citations (Scopus)

The size and behavior of the human upper airway during inhalation of aerosols

Nikander, K., Von Hollen, D. & Larhrib, E. H., 2017, In : Expert Opinion on Drug Delivery. 14, p. 1-10 10 p.

Research output: Contribution to journalArticle

Larynx
Pharynx
Aerosols
Inhalation
Mouth
3 Citations (Scopus)

The use of various organic solvents to tailor the properties of ibuprofen–glucosamine HCl solid dispersions

Nokhodchi, A., Al-Hamidi, H., Adebisi, A. O., Asare-Addo, K. & Maniruzzaman, M., Jan 2017, In : Chemical Engineering Research and Design. 117, p. 509-519 11 p.

Research output: Contribution to journalArticle

Open Access
Dispersions
Organic solvents
Dissolution
Ibuprofen
Acetone
5 Citations (Scopus)
Open Access
Surface Properties
Microscopy
Ibuprofen
Pharmaceutical Preparations
2016
25 Citations (Scopus)

Age-Mediated Changes in the Gastrointestinal Tract

Merchant, H., Liu, F., Orlu Gul, M. & Basit, A. W., 30 Oct 2016, In : International Journal of Pharmaceutics. 512, 2, p. 382-395 14 p.

Research output: Contribution to journalArticle

Open Access
File
Gastrointestinal Tract
Pharmacokinetics
Pharmaceutical Preparations
Drug Therapy
Microbiota
9 Citations (Scopus)

An assessment of triboelectrification effects on co-ground solid dispersions of carbamazepine

Adebisi, A. O., Kaialy, W., Hussain, T., Al-Hamidi, H., Nokhodchi, A., Conway, B. R. & Asare-Addo, K., 1 May 2016, In : Powder Technology. 292, p. 342-350 9 p.

Research output: Contribution to journalArticle

Open Access
Glucosamine
Carbamazepine
Dispersions
Dissolution
Charge density
5 Citations (Scopus)
Open Access
tablets
agitation
Ionic strength
Osmolar Concentration
Tablets
4 Citations (Scopus)

Effect of mechanical denaturation on surface free energy of protein powders

Mohammad, M. A., Grimsey, I. M., Forbes, R. T., Blagbrough, I. S. & Conway, B. R., Oct 2016, In : Colloids and Surfaces B: Biointerfaces. 146, p. 700-706 7 p.

Research output: Contribution to journalArticle

Open Access
Denaturation
biopolymer denaturation
Powders
Free energy
free energy
1 Citation (Scopus)

Effect of solvent on retarding the release of diltiazem HCl from Polyox-based liquisolid tablets

Kaialy, W., Bello, H., Asare-Addo, K. & Nokhodchi, A., Nov 2016, In : Journal of Pharmacy and Pharmacology. 68, 11, p. 1396-1402 7 p.

Research output: Contribution to journalArticle

Diltiazem
Tablets
Polysorbates
Pharmaceutical Preparations
Powders
6 Citations (Scopus)

Evaluation of ion exchange processes in drug-eluting embolization beads by use of an improved flow-through elution method

Swaine, T., Tang, Y., Garcia, P., John, J., Waters, L. J. & Lewis, A. L., 10 Oct 2016, In : European Journal of Pharmaceutical Sciences. 93, p. 351-359 9 p.

Research output: Contribution to journalArticle

Open Access
Ion Exchange
Pharmaceutical Preparations
irinotecan
Glass
Doxorubicin

Evaluation of Sesamum Gum as an Excipient in Matrix Tablets

Nep, E. I., Asare-Addo, K., Ngwuluka, N. C., Conway, B. & Smith, A., 14 Nov 2016, In : British Journal of Pharmacy. 1, p. 74-83 10 p.

Research output: Contribution to journalArticle

Open Access
Sesamum
Excipients
Tablets
Theophylline
Modern 1601-history
8 Citations (Scopus)

Gellan gum fluid gels for topical administration of diclofenac

Mahdi, M. H., Conway, B. R., Mills, T. & Smith, A. M., 30 Dec 2016, In : International Journal of Pharmaceutics. 515, 1-2, p. 535-542 8 p.

Research output: Contribution to journalArticle

Open Access
Topical Administration
Diclofenac
Gels
Lubrication
Pharmaceutical Preparations
7 Citations (Scopus)

Ionisation effects on the permeation of pharmaceutical compounds through silicone membrane

Waters, L. J. & Bhuiyan, A. K. M. M. H., 1 May 2016, In : Colloids and Surfaces B: Biointerfaces. 141, p. 553-557 5 p.

Research output: Contribution to journalArticle

silicones
Silicones
Permeation
Drug products
Ionization
2 Citations (Scopus)

Monitoring real time polymorphic transformation of sulfanilamide by diffuse reflectance visible spectroscopy

Ehiwe, T. O., Alexander, B. D., Mitchell, J. C., Snowden, M. J. & Waters, L. J., Jun 2016, In : Journal of Pharmaceutical Analysis. 6, 3, p. 179-183 5 p.

Research output: Contribution to journalArticle

Open Access
Spectrum Analysis
Polymorphism
Coloring Agents
Dyes
Spectroscopy
5 Citations (Scopus)

Predicting human intestinal absorption in the presence of bile salt with micellar liquid chromatography

Waters, L. J., Shokry, D. S. & Parkes, G. M. B., 1 Oct 2016, In : Biomedical Chromatography. 30, 10, p. 1618-1624 7 p.

Research output: Contribution to journalArticle

Intestinal Absorption
Liquid chromatography
Bile Acids and Salts
Liquid Chromatography
Surface-Active Agents
9 Citations (Scopus)

Selective complexation of divalent cations by a cyclic α,β-peptoid hexamer: A spectroscopic and computational study

De Santis, E., Edwards, A. A., Alexander, B. D., Holder, S. J., Biesse-Martin, A-S., Nielsen, B. V., Mistry, D., Waters, L., Siligardi, G., Hussain, R., Faure, S. & Taillefumier, C., 2016, In : Organic and Biomolecular Chemistry. 14, 48, p. 11371-11380 10 p.

Research output: Contribution to journalArticle

Open Access
Peptoids
Divalent Cations
Complexation
cations
Monovalent Cations