Pharmacology and Therapeutics Centre

Fingerprint Dive into the research topics where Pharmacology and Therapeutics Centre is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.

Microglia Medicine & Life Sciences
Cells Chemical Compounds
Neoplasms Medicine & Life Sciences
Ligands Chemical Compounds
Ruthenium Chemical Compounds
Cytotoxicity Chemical Compounds
Apoptosis Medicine & Life Sciences
Iridium Chemical Compounds

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Research Output 2014 2019

Discovery of selective, antimetastatic and anti-cancer stem cell metallohelices via post-assembly modification

Song, H., Rogers, N., Allison, S. J., Brabec, V., Bridgewater, H., Kostrhunova, H., Markova, L., Phillips, R., Pinder, E., Shepherd, S., Young, L., Zajac, J. & Scott, P., 2019, In : Chemical Science. 10, 37, p. 8547-8557 11 p.

Research output: Contribution to journalArticle

Open Access
Stem cells
Pharmaceutical Preparations
Self assembly
Adenosine Triphosphatases
1 Citation (Scopus)

Expanding the Chemical Space of Withaferin A by Incorporating Silicon to Improve its Clinical Potential on Human Ovarian Carcinoma Cells

Perestelo, N. R., LLanos, G. G., Reyes, C. P., Amesty, A., Sooda, K., Afshinjavid, S., Jiménez, I. A., Javid, F. & Bazzocchi, I. L., 9 May 2019, In : Journal of Medicinal Chemistry. 62, 9, p. 4571-4585 15 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Cell Line
Cell Cycle Resting Phase

FGFR1 Expression and Role in Migration in Low and High Grade Pediatric Gliomas

Egbivwie, N., Cockle, J. V., Humphries, M., Ismail, A., Esteves, F., Karakoula, K., Morton, R., Warr, T., Short, S. C. & Bruning-Richardson, A., 13 Mar 2019, In : Frontiers in Oncology. 9, MAR, 17 p., 103.

Research output: Contribution to journalArticle

Open Access
Receptor, Fibroblast Growth Factor, Type 1
Cell Line

Activities 2008 2019

  • 23 Poster presentation
  • 6 Invited talk
  • 2 Oral presentation

The preclinical and clinical development of Apaziquone - the trials and tribulations of working in drug development

Roger Phillips (Keynote speaker)
23 Oct 201925 Oct 2019

Activity: Talk or presentation typesInvited talk

Targeting the hypoxic fraction of cancer

Roger Phillips (Speaker)
10 Oct 2019

Activity: Talk or presentation typesInvited talk


Targeted or Phenotypic Approaches to Cancer Drug Discovery

Roger Phillips (Speaker)
4 Oct 2019

Activity: Talk or presentation typesInvited talk