Research output per year
Research output per year
Organisation profile
Research within this centre focuses on the development and evaluation of therapeutics designed to target cancer and neurological disorders. Both phenotypic evaluation of novel chemicals and the development of targeted therapeutics designed to target specific biochemical pathways that are altered in disease are areas of specific interest in this centre. The centres activities include:
- Tumour hypoxia and the tumour microenvironment
- Tumour metabolismand associated molecular vulnerabilities of cancer cells.
- Tumour Cell Migration and Invasion.
- Cellular signalling mechanisms of cell death versus proliferation/survival in normal homeostasis and in pathological conditions
- Phenotypic evaluation of novel molecules and target deconvolution
- Development of three-dimensional cell culture models
- Drugs from Nature Targeting Inflammation
- Cannabinoids in the management of disease
- Non-coding RNA networks in disease
- Biomarker discovery
- Identifying biomarkers and treatments for psychiatric disorders
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Saima Afzal
- Department of Pharmacy - Senior Lecturer in Pharmacy Practice
- Pharmaceutical Policy and Practice Research Centre - Member
- Pharmaceutics and Drug Delivery Centre - Associate Member
- Pharmacology and Therapeutics Centre - Associate Member
Person: Academic, Doctor of Philosophy
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Simon Allison
- Department of Physical and Life Sciences - Reader
- School of Applied Sciences
- Pharmacology and Therapeutics Centre - Member
- Cellular and Molecular Models of Disease Centre - Associate Membership
Person: Academic
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Anke Bruning-Richardson
- Department of Physical and Life Sciences - Senior Lecturer in Biomedicine / Pharmacology
- School of Applied Sciences
- Centre for Biomarker Research - Member
- Cellular and Molecular Models of Disease Centre - Associate Member
- Pharmacology and Therapeutics Centre - Associate Member
Person: Academic
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A novel integrative multimodal classifier to enhance the diagnosis of Parkinson's disease
Zhou, X., Parisi, L., Huang, W., Zhang, Y., Huang, X., Youseffi, M., Javid, F. & Ma, R., 1 Mar 2025, In: Briefings in Bioinformatics. 26, 2, 11 p., bbaf088.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
ARHGAP12 and ARHGAP29 exert distinct regulatory effects on switching between two cell morphological states through GSK-3 activity
Cheng, V., Vaughn-Beaucaire, P., Shaw, G. C., Kriegs, M., Droop, A., Psakis, G., Mittelbronn, M., Humphries, M., Gamboa-Esteves, F. O., Hayes, J., Cockle, J. V., Knipp, S., Rohwedder, A., Ismail, A., Rominiyi, O., Collis, S., Mavria, G., Samarasekara, J., Ladbury, J. E., Ketchen, S. E., & 14 others, 25 Mar 2025, In: Cell Reports. 44, 3, 25 p., 115361.Research output: Contribution to journal › Article › peer-review
Open Access -
Building a Solid Foundation: The Need for Causal Evidence Before Advancing Anti-Obesity Drug Development Targeting the Endocannabinoid System
Belančić, A. & Javid, F. A., 1 Feb 2025, In: Pharmacology Research and Perspectives. 13, 1, 2 p., e70056.Research output: Contribution to journal › Comment/debate › peer-review
Open Access
Projects
- 1 Finished
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Centre for Biominetic Societal Futures
Towns-Andrews, L., Kusev, P., Kara, A., Herath, D., Validi, S., Jabbar, A., Nikitas, A., Roper, S., Ginger, M., Phillips, R., Du, C., Amaratunga, D., Haigh, R., Murphy, A., Hill, R., Parkinson, S., Johnson, A., Bryan, H., Thomas, P., McIntyre, D., Jeffries, L., Bailey, R., Townsley, J., Unver, E., Goswami, P., Roach, J., Grimm, V., Worley, C., Siebers, P., Bardone, E., Madsen, J. K., Neumann, M., Seri, R., Durrant, R., Wortley, R., Sidebottom, A., Ekblom, P., Pease, K., Taylor, M., Silke, A., Dewandre, N. & Hemachandra, K.
1/10/21 → 30/09/24
Project: Research
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The potential of polymethoxyflavones as tumour controlling agents
Olumayokun Olajide (Examiner)
17 Dec 2024Activity: Examination types › PhD Examination
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External PhD Examiner at the University of Leeds
Anke Bruning-Richardson (Examiner)
16 Dec 2024Activity: Examination types › PhD Examination
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PhD External Examiner - University of Manchester
Simon Allison (Examiner)
3 Dec 2024Activity: Examination types › PhD Examination
Press/Media
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University signs MoU with Nursing and Midwifery Council of Ghana
Precious Adade Duodu, Jane Owen-Lynch, Alistair Sambell, Bibha Simkhada, Padam Simkhada, Susan Jones, Philomina Woolley, Ampem Darko Oklodu-Abbey, Dennis Addai, Hari Krishna Neupane, Manish Parajuli & Ransford Akrong
23/04/24
1 Media contribution
Press/Media: Research
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YBTC teams up with Huddersfield Uni
20/03/23
1 item of Media coverage
Press/Media: Public Engagement Activities
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Datasets
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NMR titration experiments that study binding of a NIR emitting osmium polypyridyl probe to cMYC and hTel G-quadruplex DNA
Peterková, K. (Creator), Plavec, J. (Contributor), Quinn, S. J. (Contributor), Podbevšek, P. (Contributor), Stitch, M. (Contributor), Boota, R. (Contributor), Scattergood, P. A. (Contributor) & Elliott, P. (Contributor), Zenodo, 14 Oct 2022
Dataset