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Personal profile

Biography

My first degree was in Applied Biology at the University of Hatfield I then went on to do a PhD at the University of Newcastle upon Tyne researching the mechanism of novel epithelial chloride channel blockers. I then worked at the University of Manchester in the Departments of Medicine and Pharmacy investigating intestinal drug absorption using in vitro models. After that I moved to Dundee University where my main research interest was ion transport across the lung epithelia. I returned to work in the Department of Pharmacy at Manchester and continued my interest in intestinal drug absorption and the role of P-glycoprotein. Most recently I have worked in the Department of Translational Medicine in Manchester investigating intestinal inflammation and the importance of the interaction between P-glycoprotein and the enteric micro-flora.

I was appointed as a Lecturer in Biological Sciences at Huddersfield in 2008 my main teaching is Cellular and Molecular Biology to MPharm students.

Research Expertise and Interests

  • Development of more predictive in vitro models of intestinal drug absorption 
  • Intestinal inflamation (the interaction of the gut epithelial cells with the normal enteric microflora

Research Degree Supervision

Click Here to see all postgraduate research opportunities with Dr Andrew Collett

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 4 Similar Profiles
Epithelial Cells Medicine & Life Sciences
Alopecia Medicine & Life Sciences
Lactobacillus helveticus Medicine & Life Sciences
Myeloid Differentiation Factor 88 Medicine & Life Sciences
Lactobacillus acidophilus Medicine & Life Sciences
Flagellin Medicine & Life Sciences
Drug Therapy Medicine & Life Sciences
Interferon-gamma Medicine & Life Sciences

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Research Output 2008 2018

1 Citations

A Clinical and Biological Guide for Understanding Chemotherapy-Induced Alopecia and its Prevention

Dunnill, C., Al Tameemi, W., Collett, A., Haslam, I. & Georgopoulos, N., Jan 2018, In : Oncologist. 23, 1, p. 84-96 13 p.

Research output: Contribution to journalArticle

Open Access
Alopecia
Scalp
Drug Therapy
Hair Follicle
Psychology
2 Citations

Commensal-derived OMVs Elicit a Mild Proinflammatory Response in Intestinal Epithelial Cells

Patten, D. A., Hussein, E., Davies, S. P., Humphreys, P. & Collett, A., 22 May 2017, In : Microbiology. 163, 5, p. 702-711 10 p.

Research output: Contribution to journalArticle

Open Access
Epithelial Cells
Membranes
Bacteria
Toll-Like Receptors
Microbiota
14 Citations
Lactobacillus helveticus
Lactobacillus acidophilus
HT29 Cells
Epithelial Cells
Bacterial Antigens
7 Citations

Use of in vitro human keratinocyte models to study the effect of cooling on chemotherapy drug-induced cytotoxicity

Al-Tameemi, W., Dunnill, C., Hussain, O., Komen, M. M., van den Hurk, C. J., Collett, A. & Georgopoulos, N. T., 2014, In : Toxicology in Vitro. 28, 8, p. 1366-1376 11 p.

Research output: Contribution to journalArticle

Chemotherapy
Cytotoxicity
Keratinocytes
Cooling
Drug Therapy
6 Citations

Potentiation of flagellin responses in gut epithelial cells by interferon-γ is associated with STAT-independent regulation of MyD88 expression

Bannon, C., Davies, P. J., Collett, A. & Warhurst, G., 1 Oct 2009, In : Biochemical Journal. 423, 1, p. 119-128 10 p.

Research output: Contribution to journalArticle

Myeloid Differentiation Factor 88
Flagellin
Transcription
Transducers
Interferon-gamma