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Fingerprint Dive into the research topics where Barira Islam is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

G-Quadruplexes Medicine & Life Sciences
Streptococcus mutans Medicine & Life Sciences
Molecular Dynamics Simulation Medicine & Life Sciences
Guanine Chemical Compounds
Molecular dynamics Chemical Compounds
Exome Medicine & Life Sciences
Ligands Medicine & Life Sciences
sepiapterin reductase Chemical Compounds

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Research Output 2007 2019

Mutations in TFAP2B and previously unimplicated genes of the BMP, Wnt, and Hedgehog pathways in syndromic craniosynostosis

Timberlake, A. T., Jin, S. C., Nelson-Williams, C., Wu, R., Furey, C. G., Islam, B., Haider, S., Loring, E., Galm, A., Steinbacher, D. M., Larysz, D., Staffenberg, D. A., Flores, R. L., Rodriguez, E. D., Boggon, T. J., Persing, J. A. & Lifton, R. P., 23 Jul 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 30, p. 15116-15121 6 p.

Research output: Contribution to journalArticle

Open Access
Craniosynostoses
Wnt Signaling Pathway
Mutation
Genes
Exome

Repurposing of Tranilast for Potential Neuropathic Pain Treatment by Inhibition of Sepiapterin Reductase in the BH4 Pathway

Moore, B. J. R., Islam, B., Ward, S., Jackson, O., Armitage, R., Blackburn, J., Haider, S. & Mchugh, P. C., 31 Jul 2019, In : ACS Omega. 4, 7, p. 11960-11972 13 p.

Research output: Contribution to journalArticle

Open Access
sepiapterin reductase
Molecules
Production control
Nitric oxide
Spectrophotometry
1 Citation (Scopus)

Defect in phosphoinositide signalling through a homozygous variant in PLCB3 causes a new form of spondylometaphyseal dysplasia with corneal dystrophy

Ben-Salem, S., Robbins, S. M., Lm Sobreira, N., Lyon, A., Al-Shamsi, A. M., Islam, B. K., Akawi, N. A., John, A., Thachillath, P., Al Hamed, S., Valle, D., Ali, B. R. & Al-Gazali, L., 1 Feb 2018, In : Journal of Medical Genetics. 55, 2, p. 122-130 9 p.

Research output: Contribution to journalArticle

Phosphatidylinositols
Developmental Bone Disease
Growth Disorders
Genes
Exome
15 Citations (Scopus)

Effect of Monovalent Ion Parameters on Molecular Dynamics Simulations of G-Quadruplexes

Havrila, M., Stadlbauer, P., Islam, B., Otyepka, M. & Šponer, J., 8 Aug 2017, In : Journal of Chemical Theory and Computation. 13, 8, p. 3911-3926 16 p.

Research output: Contribution to journalArticle

Molecular dynamics
Ions
molecular dynamics
Computer simulation
Positive ions
13 Citations (Scopus)

Exploring the Dynamics of Propeller Loops in Human Telomeric DNA Quadruplexes Using Atomistic Simulations

Islam, B., Stadlbauer, P., Gil-Ley, A., Pérez-Hernández, G., Haider, S., Neidle, S., Bussi, G., Banas, P., Otyepka, M. & Sponer, J., 13 Jun 2017, In : Journal of Chemical Theory and Computation. 13, 6, p. 2458-2480 23 p.

Research output: Contribution to journalArticle

Open Access
propellers
Propellers
DNA
deoxyribonucleic acid
Conformations