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Fingerprint Dive into the research topics where Barira Islam is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

G-Quadruplexes Medicine & Life Sciences
Streptococcus mutans Medicine & Life Sciences
sepiapterin reductase Chemical Compounds
Biofilms Medicine & Life Sciences
Ligands Medicine & Life Sciences
Serum Albumin Medicine & Life Sciences
Exome Medicine & Life Sciences
Aspartate-Ammonia Ligase Medicine & Life Sciences

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Research Output 2008 2019

Repurposing of Tranilast for Potential Neuropathic Pain Treatment by Inhibition of Sepiapterin Reductase in the BH4 Pathway

Moore, B. J. R., Islam, B., Ward, S., Jackson, O., Armitage, R., Blackburn, J., Haider, S. & Mchugh, P. C., 31 Jul 2019, In : ACS Omega. 4, 7, p. 11960-11972 13 p.

Research output: Contribution to journalArticle

Open Access
sepiapterin reductase
Molecules
Production control
Nitric oxide
Spectrophotometry
1 Citation (Scopus)

Defect in phosphoinositide signalling through a homozygous variant in PLCB3 causes a new form of spondylometaphyseal dysplasia with corneal dystrophy

Ben-Salem, S., Robbins, S. M., Lm Sobreira, N., Lyon, A., Al-Shamsi, A. M., Islam, B. K., Akawi, N. A., John, A., Thachillath, P., Al Hamed, S., Valle, D., Ali, B. R. & Al-Gazali, L., 1 Feb 2018, In : Journal of Medical Genetics. 55, 2, p. 122-130 9 p.

Research output: Contribution to journalArticle

Phosphatidylinositols
Developmental Bone Disease
Phospholipase C beta
Growth Disorders
Genes
14 Citations (Scopus)

Effect of Monovalent Ion Parameters on Molecular Dynamics Simulations of G-Quadruplexes

Havrila, M., Stadlbauer, P., Islam, B., Otyepka, M. & Šponer, J., 8 Aug 2017, In : Journal of Chemical Theory and Computation. 13, 8, p. 3911-3926 16 p.

Research output: Contribution to journalArticle

Molecular dynamics
Ions
molecular dynamics
Computer simulation
Positive ions
12 Citations (Scopus)

Exploring the Dynamics of Propeller Loops in Human Telomeric DNA Quadruplexes Using Atomistic Simulations

Islam, B., Stadlbauer, P., Gil-Ley, A., Pérez-Hernández, G., Haider, S., Neidle, S., Bussi, G., Banas, P., Otyepka, M. & Sponer, J., 13 Jun 2017, In : Journal of Chemical Theory and Computation. 13, 6, p. 2458-2480 23 p.

Research output: Contribution to journalArticle

Open Access
propellers
Propellers
DNA
deoxyribonucleic acid
Conformations
14 Citations (Scopus)

Can We Execute Reliable MM-PBSA Free Energy Computations of Relative Stabilities of Different Guanine Quadruplex Folds?

Islam, B., Stadlbauer, P., Neidle, S., Haider, S. & Sponer, J., 26 Feb 2016, In : Journal of Physical Chemistry B. 120, 11, p. 2899-2912 14 p.

Research output: Contribution to journalArticle

Molecular mechanics
guanines
Guanine
stems
Free energy