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Personal profile

Biography

Chris joined the Department of Chemical Sciences in October 2016 as a Senior Lecturer in Physical Chemistry. He is currently module leader for the Physics program taught to foundation year students, lectures on Molecular Spectroscopy and Surface Science to final year Physical Chemistry students and teaches postgraduate Analytical Chemistry modules along with a number of distance learning modules taken by MChem students during their sandwich year. His lab is equipped with a JEOL X-band EPR magnet, Magritek Spinsolve Carbon benchtop NMR and a high powered laser source for optically enhanced magnetic resonance experiments. Recent redevelopments in the lab have seen a second EPR magnet added dedicated to Dynamic Nuclear Polarization (DNP) studies in combination with a Bruker NMR console, and as part of a commitment to environmental sustainability a new chiller unit is being installed to reduce water consumption by providing a recirculating chilled water supply to both magnets.

Prior to moving to Huddersfield Chris was an Assistant Professor in the Department of Physics at the University of Warwick, where from April 2013 he was the Taught Course Leader of the Integrated Magnetic Resonance Centre for Doctoral Training. The EPSRC funded iMR CDT provides research-led training in all aspects of magnetic resonance to PhD students at 6 UK universities with different specialisms in magnetic resonance. Chris was responsible for organising annual residential training workshops and research conferences for the students, alongside much of the day-to-day running of the CDT. During his time as iMR CDT taught course leader Chris gained FHEA (Fellow the the Higher Education Academy) status, and he is particularly interested in the evidence base for recent changes in UK doctoral education. He is also a member of the Royal Society of Chemistry (MRSC) and contributes to a number of committees including as websmaster of the RSC ESR Spectroscopy Group, as interest group representative on the North-East Regional Steering Group and as a member of the Huddersfield Local Section committee.

Chris read Chemistry at Christ Church (University of Oxford) and completed a doctorate in the group of Prof. Christiane Timmel on the effect of radiofrequency magnetic fields on radical pair recombination reactions. He spent two years as a post-doctoral research assistant in the Clarendon Laboratory (Department of Physics) investigating molecular magnet systems whose electron-spin can code information for use in quantum information processing (QIP). In collaboration with colleagues at the University of Manchester, and using the facilities of Oxford’s interdisciplinary Centre for Advanced Electron Spin Resonance (CÆSR) based in the Inorganic Chemistry Laboratory, the team showed that the relaxation times of critical importance for QIP can be significantly improved by optimizing the molecular magnet’s chemical structure. Chris also spent time as a PDRA in Oxford’s Chemistry Department where he worked with Prof. P.J. Hore on a project using both optical spectroscopy and nuclear magnetic resonance to test in vitro the hypothesis that birds rely on radical pair reactions in the retina to detect the direction of the Earth’s magnetic field as a compass during migration. Between 2010 and 2013 Chris was a Stipendiary Lecturer in Physical Chemistry at St Hilda's College, Oxford.

Research Expertise and Interests

  • Electron Paramagnetic Resonance (EPR)
  • Spin Hyperpolarization
  • Spin Chemistry / Magnetic Field Effects

Research Degree Supervision

Fully funded EPSRC PhD studentship available on EPR of pharmaceuticals. Please click here for details of the materials DTP and look for the project "Irradiated Excipients". Application deadline 7th July 2019. Please contact Chris to discuss the project informally.

Click Here to see other postgraduate research opportunities with Dr Chris Wedge

External positions

Associate Fellow, University of Warwick

16 Nov 201630 Sep 2019

Keywords

  • Dynamic Nuclear Polarization (DNP)
  • Hyperpolarization
  • Electron Spin Resonance (ESR)
  • Electron Paramagnetic Resonance (EPR)
  • Chemically Induced Dynamic Nuclear Polarisation (CIDNP)
  • Spin Chemistry
  • Spin Trapping
  • Reaction Yield Detected Magnetic Resonance (RYDMR)
  • Time-Resolved EPR

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Paramagnetic resonance Chemical Compounds
Magnetic fields Chemical Compounds
Magnetic resonance Chemical Compounds
Magnetic field effects Chemical Compounds
electron paramagnetic resonance Physics & Astronomy
Photoexcitation Chemical Compounds
Platinum Chemical Compounds
Fullerenes Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2009 2019

Crown ether alkali metal TCNQ complexes revisited – the impact of smaller cation complexes on their solid-state architecture and properties

Bingjia Yan, Peter N Horton, Andrea E Russell, Wedge, C., Simon C Weston & Martin Christopher Grossel, 30 Apr 2019, In : CrystEngComm.

Research output: Contribution to journalArticle

Alkali Metals
Crown Ethers
Crown ethers
Alkali metals
Metal complexes
1 Citation (Scopus)

Applications of light-induced hyperpolarization in EPR and NMR

Cheney, D. & Wedge, C., 6 Nov 2018, Electron Paramagnetic Resonance. Chechik, V. & Murphy, D. M. (eds.). Royal Society of Chemistry, Vol. 26. p. 89-129 41 p. (SPR - Electron Paramagnetic Resonance).

Research output: Chapter in Book/Report/Conference proceedingChapter

Spin polarization
Photoexcitation
Magnetic resonance
Paramagnetic resonance
Nuclear magnetic resonance
3 Citations (Scopus)

Photoactivatable platinum anticancer complex can generate tryptophan radicals

Vallotto, C., Shaili, E., Shi, H., Butler, J. S., Wedge, C., Mark E Newton & Peter J Sadler, 23 Nov 2018, In : Chemical Communications. 54, 98, p. 13845-13848 4 p.

Research output: Contribution to journalArticle

Open Access
Melatonin
Platinum
Tryptophan
Pentagastrin
Hydroxyl Radical
1 Citation (Scopus)

An Electron Paramagnetic Resonance (EPR) spectroscopy study on the γ irradiation sterilization of the pharmaceutical excipient L histidine: regeneration of the radicals in solution

Vallotto, C., Williams, H. E., Murphy, D., Ayres, Z., Edge, R., Newton, M. & Wedge, C., 25 Nov 2017, In : International Journal of Pharmaceutics. 533, 1, p. 315-319 5 p.

Research output: Contribution to journalArticle

Open Access
Deamination
Excipients
Gamma Rays
Electron Spin Resonance Spectroscopy
Histidine
10 Citations (Scopus)

Mitochondria-targeted spin-labelled luminescent iridium anticancer complexes

Venkatesh, V., Berrocal-Martin, R., Wedge, C. J., Romero-Canelón, I., Sanchez-Cano, C., Song, J. I., Coverdale, J. P. C., Zhang, P., Clarkson, G. J., Habtemariam, A., Magennis, S. W., Deeth, R. J. & Sadler, P. J., 20 Oct 2017, In : Chemical Science. 8, 12, p. 8271-8278 8 p.

Research output: Contribution to journalArticle

Open Access
Iridium
Mitochondria
Cells
Spin Labels
Confocal microscopy

Activities 2014 2018

  • 7 Publication Peer-review
  • 3 Membership of committee
  • 1 Oral presentation

Journal of Physical Chemistry (Journal)

Chris Wedge (Reviewer)
2018

Activity: Publication peer-review and editorial work typesPublication Peer-review

Royal Society of Chemistry (External organisation)

Chris Wedge (Member)
20182021

Activity: Membership typesMembership of committee

Molecular Physics (Journal)

Chris Wedge (Reviewer)
2018 → …

Activity: Publication peer-review and editorial work typesPublication Peer-review

Royal Society (External organisation)

Chris Wedge (Member)
1 Jan 201731 Dec 2019

Activity: Membership typesMembership of committee

Optically Hyperpolarized Electrons for Dynamic Nuclear Polarization

Chris Wedge (Speaker)
5 Apr 2017

Activity: Talk or presentation typesOral presentation

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