Personal profile

Biography

I specialise in metallo-supramolecular chemistry, in particular the synthesis of functional complexes. This work has been recognised through invited lectures, highly cited papers and recently (2007) a cover illustration for Dalton Transactions and has resulted in 54 publications in this and other areas. I have developed the first molecular "reprogrammable" system for potential use in sensors and as metal-specific ligands, and demonstrating metal-metal communication. I received an "internationally leading" rating on my EPSRC First Grant. I collaborate with Prof. D.R. Brown (UoH), Dr A.P. Laws (UoH) and the University School of Health (lithium sensors). I work with the Universities of Bristol (Dr J.C. Jeffery) and Geneva (Dr T. Riis-Johannessen) for structural studies, and Cardiff (Dr S.J.A Pope) on luminescent supramolecular sensors. In light of this success the Department has recently procured as Bruker Apex Duo single-crystal X-ray Diffractometer.

Research Expertise and Interests

  • The synthesis of poly-dentate aromatic ligands and their application for assembly of functional supramolecular complexes.
  • Re-Programmable Molecular Systems 
  • Ditopic Cryptate-Containing Sensors

Keywords

  • Poly-Denate Aromatic Ligands
  • Functional Supramolecular Complexes
  • Re-Programmable Molecular Systems
  • Ditopic Cryptate Sensors
  • Metallo-Supramolecular Chemistry
  • Functional Complexes
  • Metal-Metal Communication
  • Metal-Specific Ligands
  • Luminescent Supramolecular Sensors

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 6 Similar Profiles
Ligands Chemical Compounds
Thiazoles Chemical Compounds
Metal ions Chemical Compounds
Ions Chemical Compounds
Crown Ethers Chemical Compounds
Metals Chemical Compounds
Rhenium Chemical Compounds
Crown ethers Engineering & Materials Science

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Research Output 2001 2018

1 Citations

Mitochondria-localising DNA-binding biscyclometalated phenyltriazole iridium(III) dipyridophenazene complexes: Syntheses and cellular imaging properties

Sreedharan, S., Sinopoli, A., Jarman, P. J., Robinson, D., Clemmet, C., Scattergood, P., Rice, C., Smythe, C. G. W., Thomas, J. & Elliott, P. 12 Mar 2018 In : Dalton Transactions. 47, 14, p. 4931-4940 11 p.

Research output: Contribution to journalArticle

Iridium
Mitochondria
Triazoles
Salts
Imaging techniques

Ruthenium-containing Linear Helicates and Mesocates with Tuneable p53 Selective Cytotoxicity in Colorectal Cancer Cells.

Rice, C., Faulkner, R., Allison, S., Cooke, D., Davidson, F. S., Elliott, P., Griffiths, H., Hussain, O., Owen-Lynch, P., Phillips, R., Shepherd, S. & Wheelhouse, R. T. 4 Jun 2018 (Accepted/In press) In : Angewandte Chemie - International Edition.

Research output: Contribution to journalArticle

Ruthenium
Cytotoxicity
Isomers
Cells
Tumors
8 Citations

An iron-catalysed C-C bond-forming spirocyclization cascade providing sustainable access to new 3D heterocyclic frameworks

Adams, K., Ball, A. K., Birkett, J., Brown, L., Chappell, B., Gill, D. M., Lo, P. K. T., Patmore, N. J., Rice, C. R., Ryan, J., Raubo, P. & Sweeney, J. B. 1 Apr 2017 In : Nature Chemistry. 9, 4, p. 396-401 6 p.

Research output: Contribution to journalArticle

Ethers
Cyclization
Iron
Metalloids
Chemical bonds

A structural study of dithizone coordination chemistry

Rice, C. R., Faulkner, R. A., Jewsbury, R. A., Bullock, S. & Dunmore, R. 2 Jun 2017 In : CrystEngComm. 19, 25, p. 3414-3419 6 p.

Research output: Contribution to journalArticle

Open Access
File
Dithizone
Metal ions
metal ions
chemistry
Deprotonation
2 Citations

Catalytic sp3-sp3 Functionalisation of Sulfonamides: Late-Stage Modification of Drug-Like Molecules

Abdulla, O., Clayton, A. D., Faulkner, R. A., Gill, D. M., Rice, C. R., Walton, S. M. & Sweeney, J. B. 31 Jan 2017 In : Chemistry - A European Journal. 23, 7, p. 1494-1497 4 p.

Research output: Contribution to journalArticle

Allylation
Sulfonamides
sigma Receptors
Molecules
Pharmaceutical Preparations