• Queensgate, Joseph Priestly

    HD1 3DH Huddersfield

Accepting PhD Students

PhD projects

Pharmaceutics, Formulation, Drug delivery and targeting to gastrointestinal tract, Oral drug delivery, Drug Absorption from the GI tract, Pharmacokinetics and Bioavailability, Bioequivalence, NAFLD and Diabetes

  • 15 h-Index
20062020

Research output per year

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Research Output

2020

Coronavirus may stay with us forever!

Merchant, H., 11 May 2020, In : The BMJ. 369, 1 p., m1790/rr-6.

Research output: Contribution to journalLetter

Open Access

CoViD-19 may not end as predicted by the SIR model

Merchant, H., 2 May 2020, In : The BMJ. 369, 1 p., m1567/rr.

Research output: Contribution to journalLetter

Open Access

Exploration of a New Source of Sustainable Nanomaterial from the Koh-e-Suleiman Mountain Range of Pakistan for Industrial Applications

Nirwan, J., Farhaj, S., Chaudhary, M. M., Khizer, Z., Hasan, S. S., Angelis-Dimakis, A., Gill, A., Rasheed, H., Abbas, N., Arshad, M. S., Hussain, T., Shahzad, Y., Yousaf, A., Chohan, T. A., Hussain, T., Merchant, H., Akram, M. R., Khan, T. M., Ashraf, M., Conway, B. & 1 others, Ghori, M. U., 17 Jan 2020, In : Scientific Reports. 10, 1, 14 p., 577.

Research output: Contribution to journalArticle

Open Access

Hand sanitisers amid CoViD-19: A critical review of alcohol-based products on the market and formulation approaches to respond to increasing demand.

Beradi, A., Perinelli, D., Merchant, H., Bisharat, L., Basheti, I., Bonacucina, G., Cespi, M. & Palmieri, G., 16 May 2020, In : International Journal of Pharmaceutics. 119431.

Research output: Contribution to journalReview article

Open Access

Is it worth the wait? Should Chloroquine or Hydroxychloroquine be allowed for immediate use in CoViD-19?

Hasan, S. S., Kow, C. S. & Merchant, H., 31 Mar 2020, In : British Journal of Pharmacy. 5, 1, 5 p., 745.

Research output: Contribution to journalReview article

Open Access

RE: Covid-19: trials of four potential treatments to generate “robust data” of what works

Merchant, H., 4 Apr 2020, In : The BMJ. 1 p., m1206/rr-1.

Research output: Contribution to journalLetter

Open Access
2019

Achieving gastroresistance without coating: Formulation of capsule shells from enteric polymers

Barbosa, J. A. C., Al-Kauraishi, M. M., Smith, A. M., Conway, B. R. & Merchant, H. A., 1 Nov 2019, In : European Journal of Pharmaceutics and Biopharmaceutics. 144, p. 174-179 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Non-steroidal topical formulation for the conditions of the skin

Merchant, H., Olajide, O. & Farzand, R., 11 Nov 2019, (Submitted) IPO UK, Patent No. GB1916398.9 (Application), 11 Nov 2019, Priority date 11 Nov 2019, Priority No. GB1916398.9

Research output: Patent

File

Using zeta potential to study the ionisation behaviour of polymers employed in modified-release dosage forms and estimating their pKa

Cunha Barbosa, J., Abdelsadig, M., Conway, B. & Merchant, H., 1 Dec 2019, In : International Journal of Pharmaceutics: X. 1, p. 1-11 11 p., 100024.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)
2018

Physiology of the Gastrointestinal System

Sauer, J-M. & Merchant, H., 2018, Comprehensive Toxicology. McQueen, C. (ed.). 3rd ed. Elsevier, p. 16-44 29 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2017

Can Diet Help Non-Obese Individuals with Non-Alcoholic Fatty Liver Disease (NAFLD)?

Merchant, H., 19 Sep 2017, In : Journal of Clinical Medicine. 6, 9, 5 p., 88.

Research output: Contribution to journalArticle

Open Access

Going Natural: Using Polymers from Nature for Gastroresistant Applications

Cunha Barbosa, J., Conway, B. & Merchant, H., 5 Jul 2017, In : British Journal of Pharmacy. 2, 1, 17 p.

Research output: Contribution to journalArticle

Open Access

Impact of Purification on Physicochemical, Surface and Functional Properties of Okra Biopolymer

Ghori, M. U., Mohammad, M. A., Rudrangi, S. R. S., Fleming, L. T., Merchant, H., Smith, A. M. & Conway, B. R., Oct 2017, In : Food Hydrocolloids. 71, p. 311-320 10 p.

Research output: Contribution to journalArticle

Open Access
18 Citations (Scopus)

Maintaining Open Access to High Quality Publications at No Cost to Authors

Conway, B. & Merchant, H., 13 Nov 2017, In : British Journal of Pharmacy. 2, 1, p. 1-2 2 p.

Research output: Contribution to journalEditorial

Open Access
2016

Age-Mediated Changes in the Gastrointestinal Tract

Merchant, H., Liu, F., Orlu Gul, M. & Basit, A. W., 30 Oct 2016, In : International Journal of Pharmaceutics. 512, 2, p. 382-395 14 p.

Research output: Contribution to journalArticle

Open Access
File
28 Citations (Scopus)

A new Open Access Journal for Research, Education and Practice in Pharmacy

Conway, B. & Merchant, H., 15 Nov 2016, In : British Journal of Pharmacy. 1, 1, p. 1-2 2 p.

Research output: Contribution to journalEditorial

Open Access
2015

Animal Farm: Considerations in Animal Gastrointestinal Physiology and Relevance to Drug Delivery in Humans

Hatton, G. B., Yadav, V., Basit, A. W. & Merchant, H., 24 Sep 2015, In : Journal of Pharmaceutical Sciences. 104, 9, p. 2747-2776 30 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

Gastrointestinal characterisation and drug solubility determination in animals

Merchant, H., Afonso-Pereira, F., Rabbie, S. C., Youssef, S. A. & Basit, A. W., May 2015, In : Journal of Pharmacy and Pharmacology. 67, 5, p. 630-639 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Gastrointestinal release behaviour of modified-release drug products: Dynamic dissolution testing of mesalazine formulations

Goyanes, A., Hatton, G. B., Merchant, H. & Basit, A. W., Apr 2015, In : International Journal of Pharmaceutics. 484, 1-2, p. 103-108 6 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)
2014

Accelerating the dissolution of enteric coatings in the upper small intestine: Evolution of a novel pH 5.6 bicarbonate buffer system to assess drug release

Varum, F. J., Merchant, H., Goyanes, A., Zboranová, V. & Basit, A. W., Jul 2014, In : International Journal of Pharmaceutics. 468, 1-2, p. 172-177 6 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Apparatus and method for testing medicaments

Merchant, H., Frost, J. & Basit, A., 25 Jun 2014, IPC No. GB2509286, Patent No. 2509286, Priority date 2 May 2012, Priority No. 1207677

Research output: Patent

Open Access
File

Influence of ageing on the gastrointestinal environment of the rat and its implications for drug delivery

Merchant, H., Rabbie, S. C., Varum, F. J. O., Afonso-Pereira, F. & Basit, A. W., 1 Oct 2014, In : European Journal of Pharmaceutical Sciences. 62, p. 76-85 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
27 Citations (Scopus)

Pulsatile drug release from electrospun poly(ethylene oxide)–sodium alginate blend nanofibres

Kaassis, A. Y. A., Young, N., Sano, N., Merchant, H., Yu, D-G. & Williams, G. R., 2014, In : Journal of Materials Chemistry. 10, p. 1400-1407 8 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2013

Colonic bacterial metabolism of corticosteroids

Yadav, V., Gaisford, S., Merchant, H. A. & Basit, A. W., 30 Nov 2013, In : International Journal of Pharmaceutics. 457, 1, p. 268-274 7 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Release of prednisolone and inulin from a new calcium-alginate chitosan-coated matrix system for colonic delivery

Araujo, V., Gamboa, A., Caro, N., Abugoch, L., Gotteland, M., Valenzuela, F., Merchant, H. A., Basit, A. W. & Tapia, C., Aug 2013, In : Journal of Pharmaceutical Sciences. 102, 8, p. 2748-2759 12 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2011

Assessment of gastrointestinal pH, fluid and lymphoid tissue in the guinea pig, rabbit and pig, and implications for their use in drug development

Merchant, H. A., McConnell, E. L., Liu, F., Ramaswamy, C., Kulkarni, R. P., Basit, A. W. & Murdan, S., 18 Jan 2011, In : European Journal of Pharmaceutical Sciences. 42, 1-2, p. 3-10 8 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)

Does sex matter? The influence of gender on gastrointestinal physiology and drug delivery

Freire, A. C., Basit, A. W., Choudhary, R., Piong, C. W. & Merchant, H. A., 30 Aug 2011, In : International Journal of Pharmaceutics. 415, 1-2, p. 15-28 14 p.

Research output: Contribution to journalReview article

86 Citations (Scopus)

Evolution of a physiological pH 6.8 bicarbonate buffer system: application to the dissolution testing of enteric coated products

Liu, F., Merchant, H. A., Kulkarni, R. P., Alkademi, M. & Basit, A. W., May 2011, In : European Journal of Pharmaceutics and Biopharmaceutics. 78, 1, p. 151-7 7 p.

Research output: Contribution to journalArticle

62 Citations (Scopus)
2010

Oral modified-release formulations in motion: the relationship between gastrointestinal transit and drug absorption

Varum, F. J. O., Merchant, H. A. & Basit, A. W., 16 Aug 2010, In : International Journal of Pharmaceutics. 395, 1-2, p. 26-36 11 p.

Research output: Contribution to journalReview article

67 Citations (Scopus)
2009

Physiological Bicarbonate Buffers: Stablisation and Use as Dissolution Media for Modified Release Systems

Merchant, H., Fadda, H. M., Arafat, B. T. & Basit, A. W., 1 Dec 2009, In : International Journal of Pharmaceutics. 382, 1-2, p. 56-60 5 p.

Research output: Contribution to journalArticle

66 Citations (Scopus)
2006

Evaluation of drug release kinetics from ibuprofen matrix tablets using HPMC

Shoaib, M. H., Tazeen, J., Merchant, H. A. & Yousuf, R. I., Apr 2006, In : Pakistan Journal of Pharmaceutical Sciences. 19, 2, p. 119-24 6 p.

Research output: Contribution to journalArticle

234 Citations (Scopus)

Once-daily tablet formulation and in vitro release evaluation of cefpodoxime using hydroxypropyl methylcellulose: a technical note

Merchant, H. A., Shoaib, H. M., Tazeen, J. & Yousuf, R., 22 Sep 2006, In : AAPS PharmSciTech. 7, 3, 6 p., 78.

Research output: Contribution to journalArticle

128 Citations (Scopus)