Hamid Merchant

Subject Leader, Department of Pharmacy
Member, Pharmaceutics and Drug Delivery Centre
Associate Member, Pharmacology and Therapeutics Centre
Associate Member, Pharmaceutical Policy and Practice Research Centre
Associate Member, Biopolymer Research Centre

Queensgate, Joseph Priestly
HD1 3DH Huddersfield

Accepting PhD Students

PhD projects

Pharmaceutics, Formulation, Drug delivery and targeting to gastrointestinal tract, Oral drug delivery, Drug Absorption from the GI tract, Pharmacokinetics and Bioavailability, Bioequivalence, NAFLD and Diabetes, Clinical Pharmaceutics and Biopharmaceutics

Source: Scopus
Calculated based on no. of publications stored in Pure and citations from Scopus

Research activity per year

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1121 Citations
16 h-Index
21 Article
9 Review article
6 Letter
3 Patent
More

43 results

2006
Evaluation of drug release kinetics from ibuprofen matrix tablets using HPMC
Shoaib, M. H., Tazeen, J., Merchant, H. A. & Yousuf, R. I., Apr 2006, In: Pakistan Journal of Pharmaceutical Sciences. 19, 2, p. 119-24 6 p.
Research output: Contribution to journal › Article › peer-review
247 Citations (Scopus)
Once-daily tablet formulation and in vitro release evaluation of cefpodoxime using hydroxypropyl methylcellulose: a technical note
Merchant, H. A., Shoaib, H. M., Tazeen, J. & Yousuf, R., 22 Sep 2006, In: AAPS PharmSciTech. 7, 3, 6 p., 78.
Research output: Contribution to journal › Article › peer-review

132 Citations (Scopus)
2009
Physiological Bicarbonate Buffers: Stablisation and Use as Dissolution Media for Modified Release Systems
Merchant, H., Fadda, H. M., Arafat, B. T. & Basit, A. W., 1 Dec 2009, In: International Journal of Pharmaceutics. 382, 1-2, p. 56-60 5 p.
Research output: Contribution to journal › Article › peer-review
73 Citations (Scopus)
2010
Oral modified-release formulations in motion: the relationship between gastrointestinal transit and drug absorption
Varum, F. J. O., Merchant, H. A. & Basit, A. W., 16 Aug 2010, In: International Journal of Pharmaceutics. 395, 1-2, p. 26-36 11 p.
Research output: Contribution to journal › Review article › peer-review
72 Citations (Scopus)
2011
Assessment of gastrointestinal pH, fluid and lymphoid tissue in the guinea pig, rabbit and pig, and implications for their use in drug development
Merchant, H. A., McConnell, E. L., Liu, F., Ramaswamy, C., Kulkarni, R. P., Basit, A. W. & Murdan, S., 18 Jan 2011, In: European Journal of Pharmaceutical Sciences. 42, 1-2, p. 3-10 8 p.
Research output: Contribution to journal › Article › peer-review
76 Citations (Scopus)
Does sex matter? The influence of gender on gastrointestinal physiology and drug delivery
Freire, A. C., Basit, A. W., Choudhary, R., Piong, C. W. & Merchant, H. A., 30 Aug 2011, In: International Journal of Pharmaceutics. 415, 1-2, p. 15-28 14 p.
Research output: Contribution to journal › Review article › peer-review
100 Citations (Scopus)
Evolution of a physiological pH 6.8 bicarbonate buffer system: application to the dissolution testing of enteric coated products
Liu, F., Merchant, H. A., Kulkarni, R. P., Alkademi, M. & Basit, A. W., May 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 78, 1, p. 151-7 7 p.
Research output: Contribution to journal › Article › peer-review
70 Citations (Scopus)
2013
Colonic bacterial metabolism of corticosteroids
Yadav, V., Gaisford, S., Merchant, H. A. & Basit, A. W., 30 Nov 2013, In: International Journal of Pharmaceutics. 457, 1, p. 268-274 7 p.
Research output: Contribution to journal › Article › peer-review
23 Citations (Scopus)
Release of prednisolone and inulin from a new calcium-alginate chitosan-coated matrix system for colonic delivery
Araujo, V., Gamboa, A., Caro, N., Abugoch, L., Gotteland, M., Valenzuela, F., Merchant, H. A., Basit, A. W. & Tapia, C., Aug 2013, In: Journal of Pharmaceutical Sciences. 102, 8, p. 2748-2759 12 p.
Research output: Contribution to journal › Article › peer-review
11 Citations (Scopus)
2014
Accelerating the dissolution of enteric coatings in the upper small intestine: Evolution of a novel pH 5.6 bicarbonate buffer system to assess drug release
Varum, F. J. O., Merchant, H., Goyanes, A., Aasi, P., Zboranová, V. & Basit, A. W., 1 Jul 2014, In: International Journal of Pharmaceutics. 468, 1-2, p. 172-177 6 p.
Research output: Contribution to journal › Article › peer-review
21 Citations (Scopus)
Apparatus and method for testing medicaments
Merchant, H., Frost, J. & Basit, A., 25 Jun 2014, IPC No. GB2509286, Patent No. 2509286, Priority date 2 May 2012, Priority No. 1207677
Research output: Patent

Open Access
File
Influence of ageing on the gastrointestinal environment of the rat and its implications for drug delivery
Merchant, H., Rabbie, S. C., Varum, F. J. O., Afonso-Pereira, F. & Basit, A. W., 1 Oct 2014, In: European Journal of Pharmaceutical Sciences. 62, p. 76-85 10 p.
Research output: Contribution to journal › Article › peer-review
10 Citations (Scopus)
Predicting the gastrointestinal behaviour of modified-release products: Utility of a novel dynamic dissolution test apparatus involving the use of bicarbonate buffers
Merchant, H., Goyanes, A., Parashar, N. & Basit, A. W., 20 Nov 2014, In: International Journal of Pharmaceutics. 475, 1-2, p. 585-591 7 p.
Research output: Contribution to journal › Article › peer-review
29 Citations (Scopus)
Pulsatile drug release from electrospun poly(ethylene oxide)–sodium alginate blend nanofibres
Kaassis, A. Y. A., Young, N., Sano, N., Merchant, H., Yu, D-G., Chatterton, N. P. & Williams, G. R., 14 Mar 2014, In: Journal of Materials Chemistry. 10, p. 1400-1407 8 p.
Research output: Contribution to journal › Article › peer-review
21 Citations (Scopus)
2015
Animal Farm: Considerations in Animal Gastrointestinal Physiology and Relevance to Drug Delivery in Humans
Hatton, G. B., Yadav, V., Basit, A. W. & Merchant, H., 24 Sep 2015, In: Journal of Pharmaceutical Sciences. 104, 9, p. 2747-2776 30 p.
Research output: Contribution to journal › Article › peer-review
66 Citations (Scopus)
Gastrointestinal characterisation and drug solubility determination in animals
Merchant, H., Afonso-Pereira, F., Rabbie, S. C., Youssef, S. A. & Basit, A. W., May 2015, In: Journal of Pharmacy and Pharmacology. 67, 5, p. 630-639 10 p.
Research output: Contribution to journal › Article › peer-review
7 Citations (Scopus)
Gastrointestinal release behaviour of modified-release drug products: Dynamic dissolution testing of mesalazine formulations
Goyanes, A., Hatton, G. B., Merchant, H. & Basit, A. W., 30 Apr 2015, In: International Journal of Pharmaceutics. 484, 1-2, p. 103-108 6 p.
Research output: Contribution to journal › Article › peer-review
41 Citations (Scopus)
2016
Age-Mediated Changes in the Gastrointestinal Tract
Merchant, H., Liu, F., Orlu Gul, M. & Basit, A. W., 30 Oct 2016, In: International Journal of Pharmaceutics. 512, 2, p. 382-395 14 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
35 Citations (Scopus)
A new Open Access Journal for Research, Education and Practice in Pharmacy
Conway, B. & Merchant, H., 15 Nov 2016, In: British Journal of Pharmacy. 1, 1, p. 1-2 2 p.
Research output: Contribution to journal › Editorial

Open Access
2017
Can Diet Help Non-Obese Individuals with Non-Alcoholic Fatty Liver Disease (NAFLD)?
Merchant, H., 19 Sep 2017, In: Journal of Clinical Medicine. 6, 9, 5 p., 88.
Research output: Contribution to journal › Article › peer-review

Open Access
Going Natural: Using Polymers from Nature for Gastroresistant Applications
Cunha Barbosa, J., Conway, B. & Merchant, H., 5 Jul 2017, In: British Journal of Pharmacy. 2, 1, 17 p.
Research output: Contribution to journal › Article › peer-review

Open Access
Impact of Purification on Physicochemical, Surface and Functional Properties of Okra Biopolymer
Ghori, M. U., Mohammad, M. A., Rudrangi, S. R. S., Fleming, L. T., Merchant, H., Smith, A. M. & Conway, B. R., 1 Oct 2017, In: Food Hydrocolloids. 71, p. 311-320 10 p.
Research output: Contribution to journal › Article › peer-review

Open Access
22 Citations (Scopus)
Maintaining Open Access to High Quality Publications at No Cost to Authors
Conway, B. & Merchant, H., 13 Nov 2017, In: British Journal of Pharmacy. 2, 1, p. 1-2 2 p.
Research output: Contribution to journal › Editorial

Open Access
2018
Physiology of the Gastrointestinal System
Sauer, J-M. & Merchant, H., 2018, Comprehensive Toxicology. McQueen, C. (ed.). 3rd ed. Elsevier, p. 16-44 29 p.
Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
1 Citation (Scopus)
2019
Achieving gastroresistance without coating: Formulation of capsule shells from enteric polymers
Barbosa, J. A. C., Al-Kauraishi, M. M., Smith, A. M., Conway, B. R. & Merchant, H. A., 1 Nov 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 144, p. 174-179 6 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
9 Citations (Scopus)
Non-steroidal topical formulation for the conditions of the skin
Merchant, H., Olajide, O. & Farzand, R., 11 Nov 2019, (Submitted) IPO UK, Patent No. 2019464.3 (Application), 10 Dec 2020, Priority date 11 Nov 2019, Priority No. GB1916398.9
Research output: Patent

File
Using zeta potential to study the ionisation behaviour of polymers employed in modified-release dosage forms and estimating their pKa
Cunha Barbosa, J., Abdelsadig, M., Conway, B. & Merchant, H., 1 Dec 2019, In: International Journal of Pharmaceutics: X. 1, p. 1-11 11 p., 100024.
Research output: Contribution to journal › Article › peer-review

Open Access
14 Citations (Scopus)
2020
Coronavirus may stay with us forever!
Merchant, H., 11 May 2020, In: The BMJ. 369, 1 p., m1790/rr-6.
Research output: Contribution to journal › Letter › peer-review

Open Access
CoViD-19: Pharmaceutical care during early disease
Merchant, H., 29 May 2020, In: The BMJ. 1 p., bmj.m2035/rr-2.
Research output: Contribution to journal › Letter › peer-review

Open Access
CoViD-19: An early intervention therapeutic strategy to prevent developing a severe disease as an alternative approach to control the pandemic
Merchant, H., 23 May 2020, 7 p. (ScienceOpen Preprints).
Research output: Working paper

Open Access
CoViD-19 may not end as predicted by the SIR model
Merchant, H., 2 May 2020, In: The BMJ. 369, 1 p., m1567/rr.
Research output: Contribution to journal › Letter › peer-review

Open Access
Dexamethasone and CoViD-19: RECOVERY trial provided invaluable clinical evidence but costed precious lives!
Merchant, H., Kow, C. S. & Hasan, S. S., 26 Jun 2020, In: The BMJ. 1 p., m2422/rr-10.
Research output: Contribution to journal › Letter › peer-review

Open Access

4 Citations (Scopus)
Exploration of a New Source of Sustainable Nanomaterial from the Koh-e-Suleiman Mountain Range of Pakistan for Industrial Applications
Nirwan, J., Farhaj, S., Chaudhary, M. M., Khizer, Z., Hasan, S. S., Angelis-Dimakis, A., Gill, A., Rasheed, H., Abbas, N., Arshad, M. S., Hussain, T., Shahzad, Y., Yousaf, A., Chohan, T. A., Hussain, T., Merchant, H., Akram, M. R., Khan, T. M., Ashraf, M., Conway, B. & 1 others, Ghori, M. U., 17 Jan 2020, In: Scientific Reports. 10, 1, 14 p., 577.
Research output: Contribution to journal › Article › peer-review

Open Access
Hand sanitisers amid CoViD-19: A critical review of alcohol-based products on the market and formulation approaches to respond to increasing demand.
Beradi, A., Perinelli, D., Merchant, H., Bisharat, L., Basheti, I., Bonacucina, G., Cespi, M. & Palmieri, G., 30 Jun 2020, In: International Journal of Pharmaceutics. 584, 14 p., 119431.
Research output: Contribution to journal › Review article › peer-review

Open Access
22 Citations (Scopus)
Is it worth the wait? Should Chloroquine or Hydroxychloroquine be allowed for immediate use in CoViD-19?
Hasan, S. S., Kow, C. S. & Merchant, H., 31 Mar 2020, In: British Journal of Pharmacy. 5, 1, 5 p., 745.
Research output: Contribution to journal › Review article › peer-review

Open Access
Mortality and Disease Severity Among COVID-19 Patients Receiving Renin-Angiotensin System Inhibitors: A Systematic Review and Meta-analysis
Hasan, S. S., Kow, C. S., Hadi, M. A., Zaidi, S. T. R. & Merchant, H. A., 1 Dec 2020, In: American Journal of Cardiovascular Drugs. 20, 6, p. 571-590 20 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
1 Citation (Scopus)
Mortality in COVID-19 patients with acute respiratory distress syndrome and corticosteroids use: a systematic review and meta-analysis
Hasan, S. S., Capstick, T., Ahmed, R., Kow, C. S., Mazhar, F., Merchant, H. A. & Zaidi, S. T. R., 1 Nov 2020, In: Expert Review of Respiratory Medicine. 14, 11, p. 1149-1163 15 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
11 Citations (Scopus)
Natural plant based delivery system: Natural plant-based coatings to improve the delivery and efficacy of nutraceuticals and traditional medicines
Merchant, H. & Abdelsadig, M., 26 Jun 2020, (Submitted) IPC No. UKPTO, Patent No. GB2009780.4, Priority date 26 Jun 2020, Priority No. GB2009780.4
Research output: Patent

File
Pharmacotherapeutic considerations for the management of diabetes mellitus among hospitalized COVID-19 patients
Hasan, S. S., Kow, C. S., Bain, A., Kavanagh, S., Merchant, H. & Abdul Hadi, M., 15 Oct 2020, In: Expert Opinion on Pharmacotherapy.
Research output: Contribution to journal › Review article › peer-review
RE: Covid-19: trials of four potential treatments to generate “robust data” of what works
Merchant, H., 4 Apr 2020, In: The BMJ. 1 p., m1206/rr-1.
Research output: Contribution to journal › Letter › peer-review

Open Access
Use of corticosteroids in asthma and COPD patients with or without COVID-19
Hasan, S. S., Capstick, T., Razi Zaidi, S. T., Kow, C. S. & Merchant, H., 1 Aug 2020, In: Respiratory Medicine. 170, 5 p., 106045.
Research output: Contribution to journal › Review article › peer-review

Open Access
3 Citations (Scopus)
Use of hydroxychloroquine and chloroquine in COVID-19: How good is the quality of randomized controlled trials?
Mazhar, F., Abdul Hadi, M., Kow, C. S., Marran, A. M. N., Merchant, H. & Hasan, S. S., 1 Dec 2020, In: International Journal of Infectious Diseases. 101, p. 107-120 14 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
Why Pfizer's or Moderna's CoViD-19 vaccine cannot be 95% effective?
Merchant, H., 30 Nov 2020, In: The BMJ. bmj.m4471/rr-3.
Research output: Contribution to journal › Letter › peer-review

Open Access

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