Personal profile

Biography

I first completed an undergraduate degree in Biomedical Sciences at the University of Aberdeen, which was followed by Doctoral research at the University of Newcastle. Within the Epithelial Research Group, I investigated the regulation of ATP binding cassette (ABC) transporters by the pregnane X receptor. This was followed by a Postdoctoral Fellowship with AstraZeneca, developing a modified Ussing chamber system to investigate cross-species intestinal absorption.

Returning to academic research, I spent 4 years working with Professor Ralf Paus at the University of Manchester. Here I developed an interest in cutaneous biology, specifically investigating mechanisms for hair follicle defence against endogenous and exogenous stressors, including oxidative and xenobiotic. In 2015 I joined the University of Huddersfield as a Senior Lecturer in Biological Sciences where I continue research into my twin interests of skin biology and active transport processes.

Research Expertise and Interests

  • Active transport processes 

External positions

Honorary Lecturer, University of Manchester

2 Nov 2015 → …

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 6 Similar Profiles
Hair Follicle Medicine & Life Sciences
Alopecia Medicine & Life Sciences
Hair Medicine & Life Sciences
Clocks Chemical Compounds
ATP-Binding Cassette Transporters Medicine & Life Sciences
Scalp Medicine & Life Sciences
Oxidative stress Chemical Compounds
Skin Medicine & Life Sciences

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Research Output 2013 2018

A Clinical and Biological Guide for Understanding Chemotherapy-Induced Alopecia and its Prevention

Dunnill, C., Al Tameemi, W., Collett, A., Haslam, I. & Georgopoulos, N. Jan 2018 In : Oncologist. 23, 1, p. 84-96 13 p.

Research output: Contribution to journalArticle

Open Access
Alopecia
Scalp
Drug Therapy
Hair Follicle
Psychology

Identifying novel strategies for treating human hair loss disorders: Cyclosporine A suppresses the Wnt inhibitor, SFRP1, in the dermal papilla of human scalp hair follicles

Hawkshaw, N. J., Hardman, J. A., Haslam, I., Shahmalak, A., Gilhar, A., Lim, X. & Paus, R. 8 May 2018 In : PLoS Biology. 16, 5, 17 p., e2003705

Research output: Contribution to journalArticle

Open Access
hair follicles
cyclosporine
Hair Follicle
alopecia
Alopecia

Organic osmolytes preserve the function of the developing tight junction in ultraviolet B-irradiated rat epidermal keratinocytes

El-Chami, C., Haslam, I. S., Steward, M. C. & O'Neill, C. A. 26 Mar 2018 In : Scientific Reports. 8, 1, 12 p., 5167

Research output: Contribution to journalArticle

Open Access
File
Tight Junctions
Keratinocytes
Tight Junction Proteins
Radiation
Cell Size
4 Citations

Oxidative Damage Control in a Human (Mini-) Organ: Nrf2 Activation Protects against Oxidative Stress-Induced Hair Growth Inhibition

Haslam, I. S., Jadkauskaite, L., Szabó, I. L., Staege, S., Hesebeck-brinckmann, J., Jenkins, G., Bhogal, R. K., Lim, F., Farjo, N., Farjo, B., Bíró, T., Schäfer, M. & Paus, R. Feb 2017 In : Journal of Investigative Dermatology. 137, 2, p. 295-304 10 p.

Research output: Contribution to journalArticle

Open Access
Oxidative stress
Hair
Oxidative Stress
Chemical activation
Hair Follicle
4 Citations

Oxidative Stress Management in the Hair Follicle: Could Targeting NRF2 Counter Age-Related Hair Disorders and Beyond?

Jadkauskaite, L., Coulombe, P. A., Schäfer, M., Dinkova-Kostova, A. T., Paus, R. & Haslam, I. Aug 2017 In : BioEssays. 39, 8, 9 p., 1700029

Research output: Contribution to journalArticle

Oxidative stress
Hair Follicle
Oxidative Stress
Aging of materials
Chemical activation