Jane Harmer

Dr

Former affiliation
20092018
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Personal profile

Biography

My first degree (1st class honours) was in Applied Biology at Cardiff University, with an industrial placement at Merck Chemicals and, following graduation in 2004, short-term work with the Centre for Research into the Environment and Health (CREH) based in Leeds. I then embarked upon a Ph.D. at Reading University (hosted jointly with Cardiff University) in the field of environmental molecular genetics investigating the inorganic speciation, biochemical fingerprinting and molecular genetic responses of Lumbricus rubellus exposed to vastly elevated concentrations of Pb and Zn in their natural environment. This work was jointly supervised by Professors John Morgan (Cardiff), Mark Hodson (Reading) and Stephen Sturzenbaum (Kings College London). Further industrial experience followed with contract work at Modern Water and Amersham Biosciences and then a short-term post-doctoral position at the Centre for Ecology and Hydrology (CEH).

In 2009 I joined the laboratories of Dr Paul McKean and Professor Michael Ginger (now at the University of Huddersfield) at Lancaster University for a post-doctoral posistion looking at the molecular and cellular biology of trypanosome parasites. More specifically we were interested in how the TBCC-domain containing protein RP2 is specifically targeted to the T. brucei basal body (centriole), work that broadened further to looking at the localisation and function of other basal body targeted and TBCC-domain containing proteins. In 2012 I side-stepped into the more technical role of Bioimaging Facilities Manager for the Department of Biomedical and Life Sciences at Lancaster University. I had responsibility for the light microscopy needs of the department including a Zeiss LSM880 laser-scanning confocal microscope and an Applied Precision DeltaVision deconvolution microscope.

I joined the Department of Biological and Geographical Sciences at the University of Huddersfield as a Senior Research Fellow in August 2017

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Oligochaeta Medicine & Life Sciences
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Trypanosomiasis Medicine & Life Sciences
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Soils Chemical Compounds
Trypanosoma brucei brucei Medicine & Life Sciences
Metals Chemical Compounds
Basal Bodies Medicine & Life Sciences

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Research Output 2009 2018

A centriolar FOP-like protein required for paraflagellar rod assembly, but not axoneme assembly in African trypanosomes: Trypanosome FOPL function

Harmer, J., Towers, K., Addison, M., Vaughan, S., McKean, P. & Ginger, M., 25 Jul 2018, In : Open Biology. 13 p.

Research output: Contribution to journalArticle

Open Access
File
Microtubule-Organizing Center
Axoneme
Trypanosomiasis
Flagella
Basal Bodies
1 Citations

Farming, slaving and enslavement: Histories of endosymbioses during kinetoplastid evolution

Harmer, J., Yurchenko, V., Nenarokova, A., Lukeš, J. & Ginger, M., 13 Jun 2018, In : Parasitology. 13 p.

Research output: Contribution to journalArticle

Slavery
Trypanosomatidae
Symbiosis
Agriculture
symbiosis
2 Citations

Variation in Basal Body Localisation and Targeting of Trypanosome RP2 and FOR20 Proteins

Harmer, J., Qi, X., Toniolo, G., Patel, A., Shaw, H., Benson, F. E., Ginger, M. L. & McKean, P. G., 1 Aug 2017, In : Protist. 168, 4, p. 452-466 15 p.

Research output: Contribution to journalArticle

Basal Bodies
Trypanosomiasis
Trypanosoma brucei brucei
Proteins
Giardia lamblia
11 Citations

Modulation of flagellum attachment zone protein FLAM3 and regulation of the cell shape in Trypanosoma brucei life cycle transitions

Sunter, J. D., Benz, C., Andre, J., Whipple, S., McKean, P. G., Gull, K., Ginger, M. L. & Lukeš, J., 15 Aug 2015, In : Journal of Cell Science. 128, 16, p. 3117-30 14 p.

Research output: Contribution to journalArticle

Open Access
Trypanosoma brucei brucei
Flagella
Cell Shape
Life Cycle Stages
Proteins
5 Citations

Platinum trimethyl bipyridyl thiolates - New, tunable, red- to near IR emitting luminophores for bioimaging applications

Steel, H. L., Allinson, S. L., Andre, J., Coogan, M. P. & Platts, J. A., 21 Jul 2015, In : Chemical Communications. 51, 57, p. 11441-11444 4 p.

Research output: Contribution to journalArticle

Open Access
2,2'-Dipyridyl
Platinum
Charge transfer
Ligands
Infrared radiation