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Personal profile

Biography

I studied biology and obtained MSc in molecular biology from the University of Warsaw, Poland, working on identification and functional aspects of mtDNA mutations in tumours. Following my interest in science education and communication, after the university I co–founded and directed Science Festival School at the International Institute for Molecular and Cell Biology in Warsaw.

Having decided to learn more and do research in evolutionary genetics, I started my PhD at the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, where I worked on metabolic and behavioural consequences of expression of putatively adaptive human genes in transgenic mice. I generated mice transgenic for genes thought to be important in human evolution, like GLUD2, a hominoid-specific gene encoding neurotransmitter-degrading enzyme glutamate dehydrogenase or a group of genes including ASPM and CENPJ that play a role in brain development and whose mutations cause microcephaly in humans. During my PhD I become more interested in functional and mechanistic basis of adaptive change, and followed this direction during a postdoc at the Max Planck Institute for Evolutionary Biology in Plön, Germany, where I worked on identification of putatively adaptive genes using whole–genome approaches. I studied copy-number variants in natural populations of Mus musculus domesticus using custom made microarrays and microsatellite scans to identify CNVs under selective sweeps.

I then switched my focus back to teaching and education and became involved in secondary and undergraduate education in the National Centre for Biotechnology Education at the University of Reading, UK, where I undertook a EU–funded project to develop practical teaching resources in synthetic biology for undergraduates. I worked on development of DNA parts, plasmids and protocols to manipulate them, as well as organised workshops for undergraduates and A-level students in synthetic biology. I helped establish and mentored the first Reading team for the International Genetically Engineered Machines competition, where the student–driven project—construction and characterisation of solar–powered, cyanobacteria-based fuel cell—was awarded a bronze medal. During a subsequent Wellcome Trust’s Society Award to NCBE, I initiated development of similar experimental synthetic biology resources for A–level students before joining University of Huddersfield.

Research Expertise and Interests

  • Evolutionary genetics 
  • Functional and mechanistic basis of adaptive change
  • Genetic mechanisms by which organisms adapt to the environment

Research Degree Supervision

Click Here to see all postgraduate research opportunities with Dr Jarek Bryk

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Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2017 2019

NextGen Biologists: Essential Computing Skills for Molecular Biology

Bryk, J., O'Connell, M. & Callaghan, M.

1/05/1730/04/19

Project: ResearchResearch Council

Research Output 2003 2018

Patterns of Ancestral Animal Codon Usage Bias Revealed Through Holozoan Protists

Southworth, J., Armitage, P., Fallon, B., Dawson, H., Bryk, J. & Carr, M., 29 Aug 2018, In : Molecular Biology and Evolution. 46 p.

Research output: Contribution to journalArticle

Open Access
File
protist
codons
Codon
gene
animal

Evolution in action: the 67 000-generation experiment

Bryk, J., 2 Oct 2017, Science in School, 41, p. 24-29 6 p.

Research output: Contribution to specialist publicationArticle

Open Access

Evolution in action: pathogens

Bryk, J., 8 Dec 2017, Science in School, 42, p. 8-13 6 p.

Research output: Contribution to specialist publicationArticle

Open Access
8 Citations

Expression of the human isoform of glutamate dehydrogenase, hGDH2, augments TCA cycle capacity and oxidative metabolism of glutamate during glucose deprivation in astrocytes

Nissen, J. D., Lykke, K., Bryk, J., Stridh, M. H., Zaganas, I., Skytt, D. M., Schousboe, A., Bak, L. K., Enard, W., Pääbo, S. & Waagepetersen, H. S., Mar 2017, In : GLIA. 65, 3, p. 474-488 15 p.

Research output: Contribution to journalArticle

Glutamate Dehydrogenase
Citric Acid Cycle
Astrocytes
Glutamic Acid
Protein Isoforms

Transcriptional effects of a positive feedback circuit in Drosophila melanogaster

Bryk, J., Reeves, R. G., Reed, F. A. & Denton, J. A., 28 Dec 2017, In : BMC Genomics. 18, 14 p., 990.

Research output: Contribution to journalArticle

Open Access
File
Drosophila melanogaster
Tetracycline
Insects
Genome
Transcriptome

Activities 2015 2018

  • 5 Membership of a Society or Institute
  • 3 Participating in a conference, workshop, ...
  • 1 Organising a conference, workshop, ...

British Ecological Society (External organisation)

Jarek Bryk (Member)
20182019

Activity: Membership typesMembership of a Society or Institute

Software Carpentry

Jarek Bryk (Organiser)
19 Jul 201720 Jul 2017

Activity: Participating in or organising an event typesOrganising a conference, workshop, ...

The Genetics Society (External organisation)

Jaroslaw Bryk (Member)
2017 → …

Activity: Membership typesMembership of a Society or Institute

The Genetics Society (External organisation)

Jarek Bryk (Member)
20172018

Activity: Membership typesMembership of a Society or Institute

Data Carpentry

Jarek Bryk (Organiser)
17 Jul 201718 Jul 2017

Activity: Participating in or organising an event typesParticipating in a conference, workshop, ...