• University of Huddersfield
    HD1 3DH

    United Kingdom

Accepting PhD Students

PhD projects

3 years fully funded (+ 12 months writing up) EPSRC project available to start Oct 2023: click on
https://www.hud.ac.uk/postgraduate/research/research-scholarships/epsrc-phd-studentships/ 'Tackling antimicrobial resistance (AMR)' project code EPSRC_2023_05
Fill out expression of interest form (closing date 19th May)
Please message me for more details.

Click on the Fingerprint icon below to learn more about the research topics, expertise and interests of this academic.

Calculated based on number of publications stored in Pure and citations from Scopus

Research activity per year

Personal profile

Research Degree Supervision

If you are interested in studying for a PhD in this research subject area click here 'Tackling antimicrobial resistance (AMR)'. Project code EPSRC_2023_05 (closing date 19 May 2023)

For more details about the research topics, expertise and interests of this academic, click on the fingerprint icon

Google Scholar h-Index

44 from 6,301 citations 

Last updated 17th April 2024


I am a protein biochemist/enzymologist with an interest in using proteins or enzymes (nature’s catalysts) as drug targets to assist in the development of new drugs and antibiotics. The in depth characterisation of the protein target can help develop more specific and effective medicines. I am also interested in looking at the production of drugs, antibiotics and high value chemicals with biotechnological applications looking at, and utilising their enzymatic pathways and cascades.

I have a PhD in Biochemistry from the University of Leicester, following a move with my supervisor from the Dept. of Pure and Applied Chemistry at the University of Strathclyde. I worked under Professor Andrew Munro at the Manchester Institute of Biotechnology (MIB) at The University of Manchester where I have been a member of a long-standing research collaboration with Professor Chris Abell’s group at the University of Cambridge. We have been characterising the drug target cytochrome P450s and other redox enzymes from the human pathogen Mycobacterium tuberculosis (the causative agent of TB). We are using structural biology and biochemical techniques to understand how these enzymes work and using the resultant crystal structures and biophysical properties of some of these enzymes to build new drug molecules. Other projects of biotechnological interest involve the characterisation of decarboxylase enzymes that make hydrocarbons like terminal alkenes, which are involved in the production of biofuels, in a joint project between the MIB and Industry.

I joined the University of Huddersfield as a Senior Lecturer in Cell Biology/Biochemistry in September 2020.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 7 - Affordable and Clean Energy
  • SDG 9 - Industry, Innovation, and Infrastructure
  • SDG 10 - Reduced Inequalities
  • SDG 12 - Responsible Consumption and Production

Research Expertise and Interests

  • Biochemistry
  • Enzymology
  • Structural biology
  • Synthetic biology
  • Antimicrobials
  • Drug Synthesis
  • Drug targeting
  • Molecular and synthetic biology of bacterial systems
  • Protein biochemistry and molecular enzymology
  • Structural biology and biophysical techniques (including UV-Vis spectroscopy, EPR, Resonance Raman spectroscopy, LC- & GC-MS)
  • Enzymes as drug targets and utilising enzyme pathways and cascades for the production of medicines and chemicals of biotechnological interest


Dive into the research topics where Kirsty McLean is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
  • 1 Similar Profiles

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or