Research Output per year
Personal profile
Biography
I did my BSc in Biochemistry & Genetics (1994-1997) and my PhD (1997-2001) in the Department of Biochemistry and Molecular Biology at the University of Leeds. I then worked as a post-doctoral research fellow firstly at the Cancer research UK Clinical centre, St James's Hospital in Leeds (2001-2005) and then at the Jack Birch Unit of Molecular Carcinogenesis, Department of Biology, University of York (2005-2008).
Research Expertise and Interests
- Studying the signalling cues that regulate cell survival versus death using appropriate epithelial cell models
- Understanding the cellular responses to death (apoptosis) signals triggered by members of the TNF Receptor protein family
- Exploring the underlying cell signalling mechanisms of a) chemotherapy-induced hair loss (alopecia) and b) defective wound healing
Research Degree Supervision
Click Here to see all postgraduate research opportunities with Dr Nikolaos Georgopoulos
Research Expertise and Interests
- Cell biology
- Cancer Research
- Immunology
- Epithelial tissues
- Cell death
- Tissue engineering
- Skin
Fingerprint Dive into the research topics where Nikolaos Georgopoulos is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 9 Similar Profiles
CD40 Ligand
Medicine & Life Sciences
Alopecia
Medicine & Life Sciences
Aquaporins
Medicine & Life Sciences
Apoptosis
Medicine & Life Sciences
Neoplasms
Medicine & Life Sciences
Reactive Oxygen Species
Medicine & Life Sciences
Aquaporin 3
Medicine & Life Sciences
Drug Therapy
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Research Output 2008 2019
CD40 induces renal cell carcinoma-specific differential regulation of TRAF proteins, ASK1 activation and JNK/p38-mediated, ROS-dependent mitochondrial apoptosis
Ibraheem, K., Yhmed, A., Qayyum, T., Bryan, N. & Georgopoulos, N. T., 4 Dec 2019, In : Cell Death Discovery. 5, 1, 14 p., 148.Research output: Contribution to journal › Article
Open Access
Tumor Necrosis Factor Receptor-Associated Peptides and Proteins
Renal Cell Carcinoma
Reactive Oxygen Species
CD40 Ligand
Apoptosis
7
Citations
(Scopus)
A Clinical and Biological Guide for Understanding Chemotherapy-Induced Alopecia and Its Prevention
Dunnill, C., Al Tameemi, W., Collett, A., Haslam, I. & Georgopoulos, N., Jan 2018, In : Oncologist. 23, 1, p. 84-96 13 p.Research output: Contribution to journal › Review article
Open Access
Alopecia
Scalp
Drug Therapy
Hair Follicle
Psychology
Expression, Localisation and Potential Significance of Aquaporins in Benign and Malignant Human Prostate Tissue
Bründl, J., Wallinger, S., Breyer, J., Weber, F., Evert, M., Georgopoulos, N. T., Rosenhammer, B., Burger, M., Otto, W. & Rubenwolf, P., 3 Sep 2018, In : BMC Urology. 18, 1, 75.Research output: Contribution to journal › Article
Open Access
Aquaporins
Prostate
Prostatic Neoplasms
Cell Line
Prostatic Hyperplasia
6
Citations
(Scopus)
A redox state-dictated signalling pathway deciphers the malignant cell specificity of CD40-mediated apoptosis
Dunnill, C. J., Ibraheem, K., Mohamed, A., Southgate, J. & Georgopoulos, N. T., 2017, In : Oncogene. 36, p. 2515-2528 14 p.Research output: Contribution to journal › Article
Open Access
Oxidation-Reduction
CD40 Ligand
Apoptosis
TNF Receptor-Associated Factor 3
Thioredoxins
Preclinical anti-cancer activity and multiple mechanisms of action of a cationic silver complex bearing N-heterocyclic carbene ligands
Allison, S. J., Sadiq, M., Baronou, E., Cooper, P. A., Dunnill, C., Georgopoulos, N. T., Latif, A., Shepherd, S., Shnyder, S. D., Stratford, I. J., Wheelhouse, R. T., Willans, C. E. & Phillips, R. M., 10 Sep 2017, In : Cancer Letters. 403, p. 98-107 10 p.Research output: Contribution to journal › Article
Open Access
Silver
Ligands
Neoplasms
dicarbine
temozolomide
Press / Media
National award for major scientific study of wound care dressings
Karen Ousey & Nikolaos Georgopoulos
19/03/19 → 20/03/19
2 items of Media coverage
Press/Media: Expert Comment