Nikolaos Georgopoulos

Reader, Department of Biological and Geographical Sciences
School of Applied Sciences
Management Group, Institute of Skin Integrity and Infection Prevention
Member, Pharmacology and Therapeutics Centre
Associate Member, Centre for Biomarker Research

Accepting PhD Students

Research output per year

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Personal profile

Biography

I did my BSc in Biochemistry & Genetics (1994-1997) and my PhD (1997-2001) in the Department of Biochemistry and Molecular Biology at the University of Leeds. I then worked as a post-doctoral research fellow firstly at the Cancer research UK Clinical centre, St James's Hospital in Leeds (2001-2005) and then at the Jack Birch Unit of Molecular Carcinogenesis, Department of Biology, University of York (2005-2008).

Research Expertise and Interests

Studying the signalling cues that regulate cell survival versus death using appropriate epithelial cell models
Understanding the cellular responses to death (apoptosis) signals triggered by members of the TNF Receptor protein family
Exploring the underlying cell signalling mechanisms of a) chemotherapy-induced hair loss (alopecia) and b) defective wound healing

Research Degree Supervision

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Research Expertise and Interests

Cell biology
Cancer Research
Immunology
Epithelial tissues
Cell death
Tissue engineering
Skin

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Research Output

27 Article
5 Patent
2 Review article
1 Short survey

CD40 induces renal cell carcinoma-specific differential regulation of TRAF proteins, ASK1 activation and JNK/p38-mediated, ROS-dependent mitochondrial apoptosis

Ibraheem, K., Yhmed, A., Qayyum, T., Bryan, N. & Georgopoulos, N. T., 4 Dec 2019, In : Cell Death Discovery. 5, 1, 14 p., 148.

Research output: Contribution to journal › Article

Open Access

A Clinical and Biological Guide for Understanding Chemotherapy-Induced Alopecia and Its Prevention

Dunnill, C., Al Tameemi, W., Collett, A., Haslam, I. & Georgopoulos, N., Jan 2018, In : Oncologist. 23, 1, p. 84-96 13 p.

Research output: Contribution to journal › Review article

Open Access

8 Citations (Scopus)

Expression, Localisation and Potential Significance of Aquaporins in Benign and Malignant Human Prostate Tissue

Bründl, J., Wallinger, S., Breyer, J., Weber, F., Evert, M., Georgopoulos, N. T., Rosenhammer, B., Burger, M., Otto, W. & Rubenwolf, P., 3 Sep 2018, In : BMC Urology. 18, 1, 75.

Research output: Contribution to journal › Article

Open Access