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Personal profile

Biography

I did my BSc in Biochemistry & Genetics (1994-1997) and my PhD (1997-2001) in the Department of Biochemistry and Molecular Biology at the University of Leeds. I then worked as a post-doctoral research fellow firstly at the Cancer research UK Clinical centre, St James's Hospital in Leeds (2001-2005) and then at the Jack Birch Unit of Molecular Carcinogenesis, Department of Biology, University of York (2005-2008).

Research Expertise and Interests

  • Studying the signalling cues that regulate cell survival versus death using appropriate epithelial cell models
  • Understanding the cellular responses to death (apoptosis) signals triggered by members of the TNF Receptor protein family
  • Exploring the underlying cell signalling mechanisms of a) chemotherapy-induced hair loss (alopecia) and b) defective wound healing

Research Degree Supervision

Click Here to see all postgraduate research opportunities with Dr Nikolaos Georgopoulos 

Keywords

  • Cell biology
  • Cancer Research
  • Immunology
  • Epithelial tissues
  • Cell death
  • Tissue engineering
  • Skin

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 8 Similar Profiles
Alopecia Medicine & Life Sciences
Aquaporins Medicine & Life Sciences
Cytotoxicity Chemical Compounds
Neoplasms Medicine & Life Sciences
Apoptosis Medicine & Life Sciences
Aquaporin 3 Medicine & Life Sciences
Drug Therapy Medicine & Life Sciences
Cells Chemical Compounds

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Research Output 2013 2018

1 Citations

A Clinical and Biological Guide for Understanding Chemotherapy-Induced Alopecia and its Prevention

Dunnill, C., Al Tameemi, W., Collett, A., Haslam, I. & Georgopoulos, N., Jan 2018, In : Oncologist. 23, 1, p. 84-96 13 p.

Research output: Contribution to journalArticle

Open Access
Alopecia
Scalp
Drug Therapy
Hair Follicle
Psychology

Expression, Localisation and Potential Significance of Aquaporins in Benign and Malignant Human Prostate Tissue

Bründl, J., Wallinger, S., Breyer, J., Weber, F., Evert, M., Georgopoulos, N. T., Rosenhammer, B., Burger, M., Otto, W. & Rubenwolf, P., 3 Sep 2018, In : BMC Urology. 18, 1, 75.

Research output: Contribution to journalArticle

Open Access
Aquaporins
Prostate
Prostatic Neoplasms
Cell Line
Prostatic Hyperplasia
3 Citations

A redox state-dictated signalling pathway deciphers the malignant cell specificity of CD40-mediated apoptosis

Dunnill, C. J., Ibraheem, K., Mohamed, A., Southgate, J. & Georgopoulos, N. T., 2017, In : Oncogene. 36, p. 2515-2528 14 p.

Research output: Contribution to journalArticle

Open Access
Oxidation-Reduction
CD40 Ligand
Apoptosis
TNF Receptor-Associated Factor 3
Thioredoxins

Preclinical anti-cancer activity and multiple mechanisms of action of a cationic silver complex bearing N-heterocyclic carbene ligands

Allison, S. J., Sadiq, M., Baronou, E., Cooper, P. A., Dunnill, C., Georgopoulos, N. T., Latif, A., Shepherd, S., Shnyder, S. D., Stratford, I. J., Wheelhouse, R. T., Willans, C. E. & Phillips, R. M., 10 Sep 2017, In : Cancer Letters. 403, p. 98-107 10 p.

Research output: Contribution to journalArticle

Open Access
Silver
Ligands
Neoplasms
dicarbine
temozolomide
53 Citations

Reactive oxygen species (ROS) and wound healing: the functional role of ROS and emerging ROS-modulating technologies for augmentation of the healing process

Dunnill, C., Patton, T., Brennan, J., Barrett, J., Dryden, M., Cooke, J., Leaper, D. & Georgopoulos, N. T., Feb 2017, In : International Wound Journal. 14, 1, p. 89-96 8 p.

Research output: Contribution to journalArticle

Open Access
Wound Healing
Reactive Oxygen Species
Technology
Wounds and Injuries
Leg Ulcer