Personal profile

Biography

Dr Olajide received his Ph.D. in Pharmacology from the University of Ibadan in Nigeria where he investigated anti-inflammatory properties of natural products. He was a Humboldt Postdoctoral Research Fellow at the Center for Drug Research (Pharmaceutical Biology), Department of Pharmacy, University of Munich, Germany where he studied cellular and molecular pharmacology of anti-inflammatory natural products, focusing on Nuclear Factor-kappa B (NF-κB) signalling. Part of his postdoctoral work was carried out in the Neurochemistry Research Laboratory, Department of Psychiatry, University of Freiburg Medical School where he conducted research on cellular and molecular pharmacology of anti-neuroinflammatory natural products.

Dr Olajide started his academic career as a Lecturer in Pharmacology in the Faculty of Pharmacy, Obafemi Awolowo University, Nigeria. He later moved to the College of Medicine, University of Ibadan, Nigeria as a Lecturer in Pharmacology. Dr Olajide had a brief stint in industry where he was involved in drug development and clinical research; he helped in developing new drugs for type 2 diabetes and atopic dermatitis. Prior to moving to Huddersfield, he was Senior Lecturer in Pharmaceutical Sciences at London Metropolitan University. Dr Olajide is on the editorial board of Evidence Based Complementary and Alternative Medicine (eCAM).

Research Expertise and Interests

  • Nuclear Factor-kappa B (NF-κB) Signalling in the Activated Microglia
  • Neuroprotection by Natural and Synthetic Steroids
  • AMPK and Nrf2 Signalling in Neuroinflammation
  • Neuroinflammation in Cerebral Malaria (CM)

Research Degree Supervision

Click Here to see all postgraduate research opportunities with Olumayokun Olajide

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Research Output 2014 2018

Activation of Nrf2 pathway contributes to neuroprotection by the dietary flavonoid tiliroside

Velagapudi, R., El-Bakoush, A. & Olajide, O. 5 Mar 2018 In : Molecular Neurobiology. 21 p.

Research output: Contribution to journalArticle

Open Access
Flavonoids
Microglia
DNA Fragmentation
Neurons
RNA Interference

Agathisflavone suppresses NF-kB-mediated release of inflammatory mediators from BV2 microglia and produces SIRT1 mediated neuroprotection in APPSwe-transfected neuronal cells

Velagapudi, R., Ajileye, O., Okorji, U. P., Jain, P., Aderogba, M. & Olajide, O. 27 Apr 2018 (Accepted/In press) In : Phytotherapy Research.

Research output: Contribution to journalArticle

4 Citations

AMPK and SIRT1 Activation Contribute to Inhibition of Neuroinflammation by Thymoquinone in BV2 Microglia

Velagapudi, R., El-Bakoush, A., Lepiarz, I., Ogunrinade, F. & Olajide, O. Nov 2017 In : Molecular and Cellular Biochemistry. 435, 1-2, p. 149-162 14 p.

Research output: Contribution to journalArticle

Open Access
Sirtuin 1
AMP-Activated Protein Kinases
Microglia
Chemical activation
Reactive Oxygen Species
6 Citations

Inhibition of neuroinflammation by thymoquinone requires activation of Nrf2/ARE signalling

Velagapudi, R., Kumar, A., Bhatia, H. S., El-Bakoush, A., Lepiarz, I., Fiebich, B. L. & Olajide, O. A. 1 Jul 2017 In : International Immunopharmacology. 48, p. 17-29 13 p.

Research output: Contribution to journalArticle

Open Access
Antioxidants
Anti-Inflammatory Agents
Microglia
Phytochemicals
Small Interfering RNA