Patrick McHugh

Reader, Department of Pharmacy
School of Applied Sciences
Director, Centre for Biomarker Research
Secondary Membership, Cellular and Molecular Models of Disease Centre

https://orcid.org/0000-0003-0661-919X

Phone01484 472074
EmailP.C.McHugh@hud.ac.uk
Websitehttps://research.hud.ac.uk

Accepting PhD Students

Source: Scopus
Calculated based on no. of publications stored in Pure and citations from Scopus

Research activity per year

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Personal profile

Google Scholar h-Index

17 Last checked 23 June 2020

Biography

Dr McHugh completed his PhD in Stem Cell model development and Pharmacogenomics, which was followed by postdoctoral work in the University of Otago’s Department of Pathology. Dr McHugh then worked as a Research Fellow in the University of Otago’s Carney Centre for Pharmacogenomics and the University of Bath’s Department of Biochemistry. In late 2011 Dr McHugh joined the University of Huddersfield as a Senior Research Fellow/Senior Lecturer in the School of Applied Science’s Department of Pharmacy. Dr McHugh’s group focuses predominantly in the key biomedical research areas of biomarker discovery and stem cell research, which encompasses several diseases/conditions including psychiatric, neurological & neurodegenerative disorders.

Research Expertise and Interests

The development of induced pluripotent stem cell models of disease.
Development of novel compounds for the treatment of CNS diseases.
The development of disease biomarkers.
The mechanism of action of CNS drugs.
The aetiology of CNS disease.

Research Degree Supervision

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Research Expertise and Interests

PCR
Cell Culture
Imminohistochemistry
Molecular Biology
Genetics
Proteins
Neurobiology
Neurodegenerative Diseases
Neurodegeneration
Neurological Diseases
Neurobiology and Brain Psychology
Neuropharmacology
Real-Time PCR
Cellular Neuroscience
Neuroprotection
Brain Diseases
Pharmacy
Neuroinflammation
Multiple Sclerosis
Neurological Disorders
Microarray Analysis
Neuron Culture
Protein Folding
Molecular Neurobiology
Neurobiochemistry
Neurochemistry
Neurogenesis
Neuronal Differentiation
Aggregation
Biology of Aging
Protein Misfolding
Tauopathies
Prion Diseases
Prion Protein
Beta Amyloid
Alpha-Synuclein

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1 Finished

Improving the understanding and treatment of neuropathic pain
McHugh, P.
1/02/14 → 31/01/16
Project: Research

473 Citations
14 h-Index
32 Article
1 Letter
1 Review article

Evolution of a maternal immune activation (mIA) model in rats: Early developmental effects
Murray, K. N., Edye, M. E., Manca, M., Vernon, A. C., Oladipo, J. M., Fasolino, V., Harte, M. K., Mason, V., Grayson, B., McHugh, P. C., Knuesel, I., Prinssen, E. P., Hager, R. & Neill, J. C., 1 Jan 2019, In: Brain, Behavior, and Immunity. 75, p. 48-59 12 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
17 Citations (Scopus)
Repurposing of Tranilast for Potential Neuropathic Pain Treatment by Inhibition of Sepiapterin Reductase in the BH4 Pathway
Moore, B. J. R., Islam, B., Ward, S., Jackson, O., Armitage, R., Blackburn, J., Haider, S. & Mchugh, P. C., 31 Jul 2019, In: ACS Omega. 4, 7, p. 11960-11972 13 p.
Research output: Contribution to journal › Article › peer-review

Open Access
5 Citations (Scopus)
Increased Oxidative Stress as a Risk Factor in Chronic Idiopathic Axonal Polyneuropathy
Zis, P., Mchugh, P. C., Manca, M., Sarrigiannis, P. G., Rao, D. G. & Hadjivassiliou, M., Dec 2018, In: Journal of Molecular Neuroscience. 66, 4, p. 547-551 5 p.
Research output: Contribution to journal › Article › peer-review

Open Access
4 Citations (Scopus)
MicroRNA quantitation during dendritic cell endocytosis using Imaging Flow Cytometry: key factors and requirements
Tong, Q., Zhu, Y., Zhang, D., Cai, Q., Qu, W., Cooper, C., Wang, J. & McHugh, P., 21 Nov 2018, In: Cellular Physiology and Biochemistry. 51, 2, p. 793-811 19 p., 2018MS533.
Research output: Contribution to journal › Article › peer-review

Open Access
Mouse maternal protein restriction during preimplantation alone permanently alters brain neuron proportion and adult short-term memory
Gould, J. M., Smith, P. J., Airey, C. J., Mort, E. J., Airey, L. E., Warricker, F. D. M., Pearson-Farr, J. E., Weston, E. C., Gould, P. J. W., Semmence, O. G., Restall, K. L., Watts, J. A., McHugh, P. C., Smith, S. J., Dewing, J. M., Fleming, T. P. & Willaime-Morawek, S., 31 Jul 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 31, p. E7398-E7407 10 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
18 Citations (Scopus)

2 PhD Examination
1 Editorial work

External PhD viva voce University of Sheffield
Patrick McHugh (Examiner)
Oct 2017
Activity: Examination types › PhD Examination
Neuroscience Letters (Journal)
Patrick McHugh (Member of editorial board)
15 Mar 2016 → …
Activity: Publication peer-review and editorial work types › Editorial work
External examiner viva voce
Patrick McHugh (Examiner)
Oct 2013
Activity: Examination types › PhD Examination