Projects per year
Personal profile
Biography
Dr McHugh completed his PhD in Stem Cell model development and Pharmacogenomics, which was followed by postdoctoral work in the University of Otago’s Department of Pathology. Dr McHugh then worked as a Research Fellow in the University of Otago’s Carney Centre for Pharmacogenomics and the University of Bath’s Department of Biochemistry. In late 2011 Dr McHugh joined the University of Huddersfield as a Senior Research Fellow/Senior Lecturer in the School of Applied Science’s Department of Pharmacy. Dr McHugh’s group focuses predominantly in the key biomedical research areas of biomarker discovery and stem cell research, which encompasses several diseases/conditions including psychiatric, neurological & neurodegenerative disorders.
Research Expertise and Interests
- The development of induced pluripotent stem cell models of disease.
- Development of novel compounds for the treatment of CNS diseases.
- The development of disease biomarkers.
- The mechanism of action of CNS drugs.
- The aetiology of CNS disease.
Research Degree Supervision
Click Here to see all postgraduate research opportunities with Dr Patrick McHugh
Keywords
- PCR
- Cell Culture
- Imminohistochemistry
- Molecular Biology
- Genetics
- Proteins
- Neurobiology
- Neurodegenerative Diseases
- Neurodegeneration
- Neurological Diseases
- Neurobiology and Brain Psychology
- Neuropharmacology
- Real-Time PCR
- Cellular Neuroscience
- Neuroprotection
- Brain Diseases
- Pharmacy
- Neuroinflammation
- Multiple Sclerosis
- Neurological Disorders
- Microarray Analysis
- Neuron Culture
- Protein Folding
- Molecular Neurobiology
- Neurobiochemistry
- Neurochemistry
- Neurogenesis
- Neuronal Differentiation
- Aggregation
- Biology of Aging
- Protein Misfolding
- Tauopathies
- Prion Diseases
- Prion Protein
- Beta Amyloid
- Alpha-Synuclein
Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.
- 1 Similar Profiles
Paroxetine
Medicine & Life Sciences
Dopamine Plasma Membrane Transport Proteins
Medicine & Life Sciences
Antidepressive Agents
Medicine & Life Sciences
Borderline Personality Disorder
Medicine & Life Sciences
beta-Synuclein
Medicine & Life Sciences
alpha-Synuclein
Medicine & Life Sciences
sepiapterin reductase
Medicine & Life Sciences
Genes
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2014 2016
- 1 Finished
Improving the understanding and treatment of neuropathic pain
1/02/14 → 31/01/16
Project: Research › UK Charity
Research Output 2001 2018
Nonsynonymous Polymorphism in Guanine Monophosphate Synthetase Is a Risk Factor for Unfavorable Thiopurine Metabolite Ratios in Patients With Inflammatory Bowel Disease
Roberts, R. L. , Wallace, M. C. , Seinen, M. L. , Van Bodegraven, A. A. , Krishnaprasad, K. , Jones, G. T. , Van Rij, A. M. , Baird, A. , Lawrance, I. C. , Prosser, R. , Bampton, P. , Grafton, R. , Simms, L. A. , Studd, C. , Bell, S. J. , Kennedy, M. A. , Halliwell, J. , Gearry, R. B. , Radford-smith, G. , Andrews, J. M. & 2 others 16 May 2018 In : Inflammatory Bowel Diseases.Research output: Contribution to journal › Article
Guanine
Ligases
Inflammatory Bowel Diseases
Single Nucleotide Polymorphism
Exome
The Development of Translational Biomarkers as a Tool for Improving the Understanding, Diagnosis and Treatment of Chronic Neuropathic Pain
Buckley, D. A., Jennings, E. M., Burke, N. N., Roche, M., McInerney, V., Wren, J. D., Finn, D. P. & McHugh, P. C. 1 Mar 2018 In : Molecular Neurobiology. 55, 3, p. 2420-2430 11 p.Research output: Contribution to journal › Article
Open Access
Neuralgia
Matrix Metalloproteinase 1
Tissue Inhibitor of Metalloproteinase-1
Chronic Pain
Biomarkers
Cognitive ability in Down syndrome and its relationship to urinary neopterin, a marker of activated cellular immunity
Zis, P., Strydom, A., Buckley, D., Adekitan, D. & Mchugh, P. C. 1 Jan 2017 In : Neuroscience Letters. 636, p. 254-257Research output: Contribution to journal › Article
Neopterin
Aptitude
Down Syndrome
Cellular Immunity
Vocabulary
Pain as a First Manifestation of Paraneoplastic Neuropathies: A Systematic Review and Meta-Analysis
Zis, P., Paladini, A., Piroli, A., McHugh, P. C., Varrassi, G. & Hadjivassiliou, M. Dec 2017 In : Pain and therapy. 6, 2, p. 143-151 9 p.Research output: Contribution to journal › Review article
Open Access
Paraneoplastic Polyneuropathy
Meta-Analysis
Pain
Paraneoplastic Syndromes
Neural Conduction
Sphingosine and dihydrosphingosine as biomarkers for multiple sclerosis identified by metabolomic profiling using coupled UPLC-MS
Ward, S., Page, M. I., McHugh, P. & Powles, N. T. 25 Sep 2017 In : Analytical Methods. 9, 41, p. 5929-5934 6 p.Research output: Contribution to journal › Article
Sphingosines
Sphingosine
Biomarkers
High performance liquid chromatography
Principal component analysis