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Last updated 17th April 2024
Biography
Dr McHugh completed his PhD in Antidepressant Pharmacogenomics in 2006, which was followed by postdoctoral work in the University of Otago’s Department of Pathology. Dr McHugh then worked as a Research Fellow in the University of Otago’s Carney Centre for Pharmacogenomics and the University of Bath’s Department of Biochemistry. In late 2011 Dr McHugh joined the University of Huddersfield as a Senior Research Fellow in the School of Applied Science’s Department of Pharmacy, with subsequent positions as Senior Lecturer and Assoc Prof/Reader in 2014 and 2016 respectively. Dr McHugh’s group focuses predominantly in the key biomedical research areas of biomarker discovery, which encompasses several diseases/conditions including neurological & neurodegenerative disorders.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research Expertise and Interests
- PCR
- Cell Culture
- Imminohistochemistry
- Molecular Biology
- Genetics
- Proteins
- Neurobiology
- Neurodegenerative Diseases
- Neurodegeneration
- Neurological Diseases
- Neurobiology and Brain Psychology
- Neuropharmacology
- Real-Time PCR
- Cellular Neuroscience
- Neuroprotection
- Brain Diseases
- Pharmacy
- Neuroinflammation
- Multiple Sclerosis
- Neurological Disorders
- Microarray Analysis
- Neuron Culture
- Protein Folding
- Molecular Neurobiology
- Neurobiochemistry
- Neurochemistry
- Neurogenesis
- Neuronal Differentiation
- Aggregation
- Biology of Aging
- Protein Misfolding
- Tauopathies
- Prion Diseases
- Prion Protein
- Beta Amyloid
- Alpha-Synuclein
- The development of disease biomarkers
- The mechanism of action of CNS drugs
- The aetiology of CNS disease
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Collaborations and top research areas from the last five years
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Projects
- 1 Finished
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Maternal Undernutrition Induces Cell Signalling and Metabolic Dysfunction in Undifferentiated Mouse Embryonic Stem Cells
Khurana, P., Cox, A., Islam, B., Eckert, J. J., Willaime-Morawek, S., Gould, J. M., Smyth, N. R., McHugh, P. C. & Fleming, T. P., 1 Apr 2023, In: Stem Cell Reviews and Reports. 19, 3, p. 767-783 17 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
The Identification of Human Translational Biomarkers of Neuropathic Pain and Cross-Species Validation Using an Animal Model
Young, B., Stephenson, J., Islam, B., Burke, N. N., Jennings, E. M., Finn, D. P. & McHugh, P. C., 1 Mar 2023, In: Molecular Neurobiology. 60, 3, p. 1179-1194 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Astragalus and human mesenchymal stem cells promote wound healing by mediating immunomodulatory effects through paracrine signaling
Wang, J., Zhang, D., Zhu, Y., Mo, X., McHugh, P. & Tong, Q., 1 Apr 2022, In: Regenerative Medicine. 17, 4, p. 219-232 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus) -
SLC19A1 Genetic Variation Leads to Altered Thiamine Diphosphate Transport: Implications for the Risk of Developing Wernicke-Korsakoff's Syndrome
O'Brien, N. L., Quadri, G., Lightley, I., Sharp, S. I., Guerrini, I., Smith, I., Heydtmann, M., Morgan, M. Y., Thomson, A. D., Bass, N. J., McHugh, P. C. & McQuillin, A., 10 Sep 2022, In: Alcohol and Alcoholism. 57, 5, p. 581-588 8 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
The Identification of Blood Biomarkers of Chronic Neuropathic Pain by Comparative Transcriptomics
Islam, B., Stephenson, J., Young, B., Manca, M., Buckley, D., Radford, H., Zis, P., Johnson, M., Finn, D. & McHugh, P., 1 Sep 2022, In: NeuroMolecular Medicine. 24, 3, p. 320-338 19 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Citations (Scopus)
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External PhD viva voce University of Sheffield
Patrick McHugh (Examiner)
Oct 2017Activity: Examination types › PhD Examination
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Neuroscience Letters (Journal)
Patrick McHugh (Member of editorial board)
15 Mar 2016 → …Activity: Publication peer-review and editorial work types › Editorial work
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External examiner viva voce
Patrick McHugh (Examiner)
Oct 2013Activity: Examination types › PhD Examination