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Last updated 5th June 2026
Biography
Dr McHugh completed his PhD in Antidepressant Pharmacogenomics in 2006, which was followed by postdoctoral work in the University of Otago’s Department of Pathology. Dr McHugh then worked as a Research Fellow in the University of Otago’s Carney Centre for Pharmacogenomics and the University of Bath’s Department of Biochemistry. In late 2011 Dr McHugh joined the University of Huddersfield as a Senior Research Fellow in the School of Applied Science’s Department of Pharmacy, with subsequent positions as Senior Lecturer and Assoc Prof/Reader in 2014 and 2016 respectively. Dr McHugh’s group focuses predominantly in the key biomedical research areas of biomarker discovery, which encompasses several diseases/conditions including neurological & neurodegenerative disorders.
Research Expertise and Interests
- PCR
- Cell Culture
- Imminohistochemistry
- Molecular Biology
- Genetics
- Proteins
- Neurobiology
- Neurodegenerative Diseases
- Neurodegeneration
- Neurological Diseases
- Neurobiology and Brain Psychology
- Neuropharmacology
- Real-Time PCR
- Cellular Neuroscience
- Neuroprotection
- Brain Diseases
- Pharmacy
- Neuroinflammation
- Multiple Sclerosis
- Neurological Disorders
- Microarray Analysis
- Neuron Culture
- Protein Folding
- Molecular Neurobiology
- Neurobiochemistry
- Neurochemistry
- Neurogenesis
- Neuronal Differentiation
- Aggregation
- Biology of Aging
- Protein Misfolding
- Tauopathies
- Prion Diseases
- Prion Protein
- Beta Amyloid
- Alpha-Synuclein
- The development of disease biomarkers
- The mechanism of action of CNS drugs
- The aetiology of CNS disease
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 2 Zero Hunger -
SDG 3 Good Health and Well-being -
SDG 9 Industry, Innovation, and Infrastructure
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Collaborations and top research areas from the last five years
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Projects
- 1 Finished
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Improving the understanding and treatment of neuropathic pain
McHugh, P. (PI)
1/02/14 → 31/01/16
Project: Research
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Maternal high-fat diet, during preimplantation or gestation-lactation, alters mouse offspring metabolic, molecular and locomotor phenotypes
Peral-Sanchez, I., Sezer, E., Ojeda, D., Calder, P., McHugh, P., Morris, R., Norman, J., Ward, J., Fleming, T., Eckert, J., Smyth, N. & Willaime-Morawek, S., 12 Aug 2026, (Accepted/In press) In: Journal of Nutrition and Metabolism.Research output: Contribution to journal › Article › peer-review
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Clinical measures in chronic neuropathic pain are related to the Kennedy and endocannabinoid pathways
Bourke, S., Suarez-Gonzalez, E., Islam, B., Stephenson, J., Finn, D. P. & McHugh, P., 1 Feb 2025, In: European Journal of Clinical Investigation. 55, 2, 13 p., e14351.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Citations (Scopus) -
Maternal Undernutrition Induces Cell Signalling and Metabolic Dysfunction in Undifferentiated Mouse Embryonic Stem Cells
Khurana, P., Cox, A., Islam, B., Eckert, J. J., Willaime-Morawek, S., Gould, J. M., Smyth, N. R., McHugh, P. C. & Fleming, T. P., 1 Apr 2023, In: Stem Cell Reviews and Reports. 19, 3, p. 767-783 17 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Link opens in a new tab Citations (Scopus) -
The Identification of Human Translational Biomarkers of Neuropathic Pain and Cross-Species Validation Using an Animal Model
Young, B., Stephenson, J., Islam, B., Burke, N. N., Jennings, E. M., Finn, D. P. & McHugh, P. C., 1 Mar 2023, In: Molecular Neurobiology. 60, 3, p. 1179-1194 16 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Link opens in a new tab Citations (Scopus) -
Astragalus and human mesenchymal stem cells promote wound healing by mediating immunomodulatory effects through paracrine signaling
Wang, J., Zhang, D., Zhu, Y., Mo, X., McHugh, P. & Tong, Q., 1 Apr 2022, In: Regenerative Medicine. 17, 4, p. 219-232 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Link opens in a new tab Citations (Scopus)
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External PhD viva voce University of Sheffield
McHugh, P. (Examiner)
Oct 2017Activity: Examination types › PhD Examination
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Neuroscience Letters (Journal)
McHugh, P. (Member of editorial board)
15 Mar 2016 → …Activity: Publication peer-review and editorial work types › Editorial work
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External examiner viva voce
McHugh, P. (Examiner)
Oct 2013Activity: Examination types › PhD Examination