Personal profile

Biography

I first developed an interest in structural molecular biology during my undergraduate degree at the University of Sheffield. To pursue this interest, I studied for a PhD in X-ray crystallography at the Astbury Centre for Structural Molecular Biology, University of Leeds under the supervision of Prof. Simon Phillips. I then worked as a postdoctoral research fellow under the supervision of Prof. Steve Homans and Prof. Steve Baldwin. By studying how a range of small molecules bind to the hydrophobic pocket of a small protein, we were able to demonstrate that hydrophobic ligand-protein interactions can be enthalpy driven with a significant contribution from London dispersion forces.

In 2006, I started a postdoctoral position at the University of York work under the supervision of Prof. Jennifer Potts on fibronectin-binding proteins from pathogenic bacteria, elucidating mechanisms of the beta-zipper interaction.

I joined the Department of Biological Sciences at the University of Huddersfield in September 2008.

Research Expertise and Interests

  • The causative agent of Lyme Disease - Borrelia burgdorferi

Research Degree Supervision

Click Here to see all postgraduate research opportunities with Dr Richard Bingham

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Fibronectins Medicine & Life Sciences
Thermodynamics Medicine & Life Sciences
Ligands Medicine & Life Sciences
Proteins Medicine & Life Sciences
Binding Sites Medicine & Life Sciences
Calorimetry Medicine & Life Sciences
Peptidyl-Dipeptidase A Medicine & Life Sciences
Gelatin Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2004 2017

2 Citations

Mesoscopic structure of pectin in solution

Alba, K., Bingham, R. J. & Kontogiorgos, V. 1 Jun 2017 In : Biopolymers. 107, 6, 8 p., e23016

Research output: Contribution to journalArticle

Open Access
Conformations
Scattering
Biopolymers
Fractal dimension
Polysaccharides
5 Citations

Pectin isolation and characterization from six okra genotypes

Kpodo, F. M., Agbenorhevi, J. K., Alba, K., Bingham, R., Oduro, I. N., Morris, G. A. & Kontogiorgos, V. 1 Nov 2017 In : Food Hydrocolloids. 72, p. 323-330 8 p.

Research output: Contribution to journalArticle

Open Access
Abelmoschus
okra
Sugars
pectins
Genotype
3 Citations

The Borrelia afzelii outer membrane protein BAPKO0422 binds human Factor-H and is predicted to form a membrane-spanning beta-barrel

Dyer, A., Brown, G., Stejskal, L., Laity, P. R. & Bingham, R. 1 Aug 2015 In : Bioscience Reports. 35, 4, p. e00240

Research output: Contribution to journalArticle

Open Access
Borrelia burgdorferi Group
Spirochaetales
Borrelia
Proteobacteria
Membrane Proteins
35 Citations

Staphylococcal biofilm-forming protein has a contiguous rod-like structure

Gruszka, D. T., Wojdyla, J. A., Bingham, R. J., Turkenburg, J. P., Manfield, I. W., Steward, A., Leech, A. P., Geoghegan, J. A., Foster, T. J., Clarke, J. & Potts, J. R. 24 Apr 2012 In : Proceedings of the National Academy of Sciences of the United States of America. 109, 17, p. E1011-E1018

Research output: Contribution to journalArticle

Biofilms
Membrane Proteins
Staphylococcus aureus
Proteins
Protein S
4 Citations

Structural basis of peptide recognition by the angiotensin-1 converting enzyme homologue AnCE from Drosophila melanogaster

Akif, M., Masuyer, G., Bingham, R. J., Sturrock, E. D., Isaac, R. E. & Acharya, K. R. Dec 2012 In : FEBS Journal. 279, 24, p. 4525-4534 10 p.

Research output: Contribution to journalArticle

Angiotensins
Peptidyl-Dipeptidase A
Drosophila melanogaster
Bradykinin
Thr(6)-bradykinin