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Last updated 20th March 2026
Biography
I first developed an interest in structural molecular biology during my undergraduate degree at the University of Sheffield. To pursue this interest, I studied for a PhD in X-ray crystallography at the Astbury Centre for Structural Molecular Biology, University of Leeds under the supervision of Prof. Simon Phillips. I then worked as a postdoctoral research fellow under the supervision of Prof. Steve Homans and Prof. Steve Baldwin. By studying how a range of small molecules bind to the hydrophobic pocket of a small protein, we were able to demonstrate that hydrophobic ligand-protein interactions can be enthalpy driven with a significant contribution from London dispersion forces.
In 2006, I started a postdoctoral position at the University of York work under the supervision of Prof. Jennifer Potts on fibronectin-binding proteins from pathogenic bacteria, elucidating mechanisms of the beta-zipper interaction.
I joined the Department of Biological Sciences at the University of Huddersfield in September 2008.
Research Expertise and Interests
- The causative agent of Lyme Disease - Borrelia burgdorferi
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 9 Industry, Innovation, and Infrastructure
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Collaborations and top research areas from the last five years
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Borrelia BBJ25 is a plasmid-encoded Omp85-family protein associated with a potential export system
Nixon, A., Soliman, E., Bryk, J., Carr, M., Cooper, C. D. O. & Bingham, R. J., 6 Feb 2026, In: Bioscience Reports. 46, 2, 12 p., BSR20254082.Research output: Contribution to journal › Article › peer-review
Open Access -
Crystal structure and molecular dynamics of human POLDIP2, a multifaceted adaptor protein in metabolism and genome stability
Kulik, A., Maruszczak, K., Thomas, D., Nabi, N., Carr, M., Bingham, R. & Cooper, C., 1 Jun 2021, In: Protein Science. 30, 6, p. 1196-1209 14 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Link opens in a new tab Citations (Scopus) -
Flexibility and intrinsic disorder are conserved features of hepatitis C virus E2 glycoprotein
Stejskal, L., Lees, W. D., Moss, D. S., Palor, M., Bingham, R. J., Shepherd, A. J. & Grove, J., 28 Feb 2020, In: PLoS Computational Biology. 16, 2, 29 p., e1007710.Research output: Contribution to journal › Article › peer-review
Open Access22 Link opens in a new tab Citations (Scopus) -
Expression, purification and metal utilization of recombinant SodA from Borrelia burgdorferi
Brown, G., Broxham, A. H., Cherrington, S. E., Thomas, D. C., Dyer, A., Stejskal, L. & Bingham, R. J., 1 Nov 2019, In: Protein Expression and Purification. 163, 6 p., 105447.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Link opens in a new tab Citation (Scopus) -
Pectin Conformation in Solution
Alba, J., Bingham, R., Gunning, P., Wilde, P. & Kontogiorgos, V., 26 Jul 2018, In: Journal of Physical Chemistry B. 122, 29, p. 7286-7294 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile84 Link opens in a new tab Citations (Scopus)
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Pathogens (Journal)
Bingham, R. (Reviewer)
12 Dec 2019 → …Activity: Publication peer-review and editorial work types › Publication Peer-review
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Antibiotics (Journal)
Bingham, R. (Reviewer)
2019 → …Activity: Publication peer-review and editorial work types › Publication Peer-review
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Royal Society of Biology (External organisation)
Bingham, R. (Member)
2019 → 2025Activity: Membership types › Membership of a Society or Institute
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Frontiers in Molecular Biosciences (Journal)
Bingham, R. (Editor)
2018 → 2019Activity: Publication peer-review and editorial work types › Editorial work
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Healthcare (Journal)
Bingham, R. (Reviewer)
2018 → …Activity: Publication peer-review and editorial work types › Publication Peer-review