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Last updated 17th April 2024
Biography
Professor Roger Phillips was appointed Professor of Cancer Pharmacology in July 2014.
Following a BSc in Marine Biology and Biochemistry (Joint Honours) from University College of North Wales, Bangor, Roger specialised in Cancer Pharmacology gaining his PhD in 1988 from the University of Bradford (under Profs John Double and Mike Bibby). After an initial postdoctoral position in Bradford, he moved to the School of Pharmacy, University of Southern California, Los Angeles to work with Dr Neil Gibson in 1991. He returned to Bradford in 1993 and secured academic appointments as lecturer (1996 to 2001), Senior Lecturer (2001 to 2003) and Reader (2003 to 1014) in Cancer Pharmacology. In July 2014, Roger was appointed as Professor of Cancer Pharmacology at the University of Huddersfield. He was also appointed as Director of Research in the School of Applied Sciences in August 2015.
His research focuses on the preclinical and early clinical evaluation of novel anti-cancer drugs with a specific interest in the tumour microenvironment as a target for drug development. His research has had clinical impact through the development of EO9 as a therapeutic drug for the treatment of superficial bladder cancer. He has published extensively in internationally recognised journals, has successfully supervised over 20 PhD students and continues to present his work at national and international conferences. He is a committee member of the European Organisation for the Research and Treatment of Cancer (EORTC) Drug Development Committee and the Pharmacology and Molecular Mechanism Group. He is also an editorial board member for the British Journal of Pharmacology.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research Expertise and Interests
- Biochemistry
- Molecular Medicine
- Cancer Research
- Drug Development
- Biomarker Research
- Pharmaceutics
- Preclinical development of novel anti-cancer drugs
- Phenotype based screening
- Development of experimental models that reflect the complexity of tumour biology
- The hypoxic tumour microenvironment as a target for drug development
- Drug delivery to hypoxic regions of solid tumours
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Collaborations and top research areas from the last five years
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Projects
- 1 Finished
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Centre for Biominetic Societal Futures
Towns-Andrews, L., Kusev, P., Kara, A., Herath, D., Validi, S., Jabbar, A., Nikitas, A., Roper, S., Ginger, M., Phillips, R., Du, C., Amaratunga, D., Haigh, R., Murphy, A., Hill, R., Parkinson, S., Johnson, A., Bryan, H., Thomas, P., McIntyre, D., Jeffries, L., Bailey, R., Townsley, J., Unver, E., Goswami, P., Roach, J., Grimm, V., Worley, C., Siebers, P., Bardone, E., Madsen, J. K., Neumann, M., Seri, R., Durrant, R., Wortley, R., Sidebottom, A., Ekblom, P., Pease, K., Taylor, M., Silke, A., Dewandre, N. & Hemachandra, K.
1/10/21 → 30/09/24
Project: Research
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The interaction of phosphate species with cerium oxide: The known, the ambiguous and the unexplained
Ta, K. M., Neal, C. J., Coathup, M. J., Seal, S., Phillips, R. M. & Molinari, M., 1 Jan 2025, In: Biomaterials Advances. 166, 12 p., 214063.Research output: Contribution to journal › Review article › peer-review
Open Access -
Dicobalt(ii) helices kill colon cancer cells via enantiomer-specific mechanisms: DNA damage or microtubule disruption
Song, H., Kostrhunova, H., Cervinka, J., Macpherson, J., Malina, J., Rajan, T., Phillips, R., Postings, M., Shepherd, S., Zhang, X., Brabec, V., Rogers, N. J. & Scott, P., 28 Jul 2024, In: Chemical Science. 15, 28, p. 11029-11037 9 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Preclinical Evaluation of Zn(II) Self-Assemblies with Selective Cytotoxic Activity Against Cancer Cells In Vitro and In Ovo
Allison, S. J., Ashton, G. P., Lynch, H. J., Shire, B. R., Phillips, R. M., Parkes, G. M. B., Pinder, E., Rice, C. R., Teixeira, A. A. M., Volleman, T. & Wordsworth, D. A., 11 Jan 2024, In: Chemistry - A European Journal. 30, 3, 7 p., e202302803.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Cross-species oncogenomics offers insight into human muscle-invasive bladder cancer
Wong, K., Abascal, F., Ludwig, L., Aupperle-Lellbach, H., Grassinger, J., Wright, C. W., Allison, S. J., Pinder, E., Phillips, R., Romero, L. P., Gal, A., Roady, P. J., Pires, I., Guscetti, F., Munday, J. S., Peleteiro, M. C., Pinto, C. A., Carvalho, T., Cota, J., Du Plessis, E. C., & 34 others, 1 Dec 2023, In: Genome Biology. 24, 1, 29 p., 191.Research output: Contribution to journal › Article › peer-review
Open Access8 Citations (Scopus) -
Cytotoxicity of Ruthenium(II) Arene Complexes Containing Functionalized Ferrocenyl β-Diketonate Ligands
Allison, M., Caramés-Méndez, P., Hofmann, B. J., Pask, C. M., Phillips, R. M., Lord, R. M. & McGowan, P. C., 14 Aug 2023, In: Organometallics. 42, 15, p. 1869-1881 13 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Citations (Scopus)
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International Conference On Drug Discovery And Translational Medicine 2023
Roger Phillips (Member of programme committee)
4 Dec 2023 → 8 Dec 2023Activity: Participating in or organising an event types › Participating in a conference, workshop, ...
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Site-specific differences in articular cartilage thickness and the composition of the extracellular and pericellular matrix
Laura Weimer (Speaker), Anna Rapp (Contributor to Paper or Presentation), Roger Phillips (Contributor to Paper or Presentation), Alan Smith (Contributor to Paper or Presentation), Frank Zaucke (Contributor to Paper or Presentation) & Ilona Braendlin (Contributor to Paper or Presentation)
9 Sep 2023Activity: Talk or presentation types › Poster presentation
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The effect of ceria surface composition on scavenging reactive oxygen species
Khoa Ta (Speaker), David Cooke (Contributor to Paper or Presentation), Lisa Gillie (Contributor to Paper or Presentation), Roger Phillips (Contributor to Paper or Presentation) & Marco Molinari (Contributor to Paper or Presentation)
29 Jun 2023Activity: Talk or presentation types › Oral presentation
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External PhD Examiner at University Putra Malaysia
Roger Phillips (Examiner)
23 Jun 2023Activity: Examination types › PhD Examination
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The development of EO9 as a loco-regional therapy for superficial bladder cancer
Roger Phillips (Speaker)
25 Apr 2023Activity: Talk or presentation types › Oral presentation