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Personal profile

Biography

I completed my undergraduate honours degree in 2010 with a supervised work placement within the Hygiene and Disinfection Laboratory at the University of Huddersfield. I then became laboratory supervisor of the laboratory until beginning my PhD in 2011. I successfully completed my PhD in 2016 undertaking the research project 'Biodegradation of alkaline cellulose degradation products' as part of the EPSRC/RWM Ltd funded C14-BIG project.

I continued the theme of alkaline microbiology linked to a geological disposal concept for nuclear waste during my post-doctoral position, investigating survival strategies such as aggregation and biofilm formation on nuclear relevant materials. As a source of alkaliphilic micro-organisms, industrially contaminated soils and microbial communities present were also a research focus resulting in 14 publications. 

Throughout my postgraduate and postdoctoral studies I have continued to work within the Hygiene and Disinfection Laboratory working with a number of industrial clients carrying out both bespoke and standard (BSEN, AOAC, ASTM) testing methods. This has been the focus for my position within the Microbial Therapeutics and Infection Centre providing specialised work projects for industrial partnerships. In 2017, I worked on a BBSRC/Innovate UK funded project investigating the use of efflux pump inhibitors to improve biocide efficacy against Pseudomonas aeruginosa in collaboration with Gama Healthcare. In 2017, I also worked on an Innovate UK funded collaboration with ADM Protexin Ltd investigating the anti-Candida properties of probiotic micro-organisms.

 In 2018 I was appointed Lecturer within the School of Applied Sciences, providing teaching in Biological and Geographical Sciences. I am also co-supervisor to 3 PhD students. These projects include the alkaline treatment of cellulosic waste materials for biogas and bioenergy production, the use of efflux pump inhibitors to improve biocidal efficacy against hospital pathaogens and the dietary influence of diet (vegan, raw food, western) on the gut metagenome. In addition I am supervisor to an MRes student determining the microbial gut populations of the same individuals.  

Keywords

  • Alkaliphiles
  • Biogas
  • Bioenergy
  • Biofilms
  • Extracellular polysaccharides
  • Antimicrobials
  • Probiotics

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Research Output 2012 2019

Genomic Insights Into A Novel, Alkalitolerant Nitrogen Fixing Bacteria, Azonexus sp. Strain ZS02.

Salah, Z., Charles, C., Humphreys, P., Laws, A. & Rout, S., 1 Jan 2019, In : Journal of Genomics. 7, 6 p.

Research output: Contribution to journalArticle

Open Access
File
Bacteria
Nitrogen
Genes
Antiporters
Genome Size

In-situ Biofilm Formation in Hyper Alkaline Environments

Charles, C., Rout, S., Wormald, R., Laws, A., Jackson, B. R., Boxall, S. A. & Humphreys, P., 19 Dec 2018, (Accepted/In press) In : Geomicrobiology Journal. 9 p.

Research output: Contribution to journalArticle

6 Citations

Sustained Bauxite Residue Rehabilitation with Gypsum and Organic Matter 16 years after Initial Treatment

Bray, A. W., Stewart, D. I., Courtney, R., Rout, S. P., Humphreys, P. N., Mayes, W. M. & Burke, I. T., 2 Jan 2018, In : Environmental Science & Technology. 52, 1, p. 152-161 10 p.

Research output: Contribution to journalArticle

Open Access
File
Calcium Sulfate
Aluminum Oxide
bauxite
Patient rehabilitation
Biological materials

The Impact of Alkaliphilic Biofilm Formation on the Release and Retention of Carbon Isotopes from Nuclear Reactor Graphite

Rout, S., Payne, L., Walker, S., Scott, T., Heard, P., Eccles, H., Bond, G., Shah, P., Bills, P., Jackson, B. R., Boxall, S. A., Laws, A., Charles, C., Williams, S. J. & Humphreys, P., 13 Mar 2018, In : Scientific Reports. 8, 9 p., 4455.

Research output: Contribution to journalArticle

Open Access
graphite
biofilm
carbon isotope
porosity
nuclear power plant
3 Citations

Floc Formation Reduces the pH Stress Experienced by Microorganisms Living in Alkaline Environments

Charles, C. J., Rout, S. P., Patel, K. A., Akbar, S., Laws, A. P., Jackson, B. R., Boxall, S. A. & Humphreys, P. N., 1 Mar 2017, In : Applied and Environmental Microbiology. 83, 6, 32 p.

Research output: Contribution to journalArticle

Open Access
alkaline environment
microorganism
microorganisms
radioactive waste
Radioactive Waste