Tarja Kinnunen

Subject Leader Biological Sciences, Department of Biological and Geographical Sciences
School of Applied Sciences
Member, Cellular and Molecular Models of Disease Centre

Phone01484 472008
EmailT.Kinnunen@hud.ac.uk
Websitehttps://research.hud.ac.uk

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Personal profile

Biography

I did my PhD at the Institute of Biotechnology and University of Helsinki, Finland, combining developmental neurobiology and glycobiology to study mechanisms of syndecan-3 mediated neurite outgrowth using mammalian models. As an EMBO Long-Term Fellow and subsequently as a Wellcome Trust Advanced Training Fellow at the University of Birmingham, I translated my cell biology and biochemistry background into the use of the nematode C. elegans as a genetic model organism. As an MRC New Investigator at the University of Liverpool, my research interest into glycosylated membrane proteins expanded from heparan sulphate proteoglycans to fibroblast growth factor (FGF) and Klotho signalling in development and metabolic physiology. In December 2012 I was appointed as a Senior Lecturer at the University of Huddersfield.

Research Expertise and Interests

Glycosylation as a regulator of development
Metabolic physiology and disease

Research Degree Supervision

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2 Similar Profiles

Heparitin Sulfate Medicine & Life Sciences

Caenorhabditis elegans Medicine & Life Sciences

Fibroblast Growth Factor Receptors Medicine & Life Sciences

Heparan Sulfate Proteoglycans Medicine & Life Sciences

Glypicans Medicine & Life Sciences

Cell Movement Medicine & Life Sciences

Syndecans Medicine & Life Sciences

Sulfotransferases Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2015 2017

1 Finished

C. elegans model to unravel the role of Klotho in ion metabolism and aging

Kinnunen, T.

1/01/15 → 31/12/17

Project: Research

Research Output 2003 2020

10 Article
1 Review article

Functional validity, role, and implications of heavy alcohol consumption genetic loci

Thompson, A., Cook, J., Choquet, H., Jorgenson, E., Yin, J., Kinnunen, T., Barclay, J., Morris, A. P. & Pirmohamed, M., 15 Jan 2020, In : Science advances. 6, 3, 12 p., eaay5034.

Research output: Contribution to journal › Article

Open Access

Genetic Loci

Alcohol Drinking

Alcohols

Gout

Caenorhabditis elegans

21 Citations (Scopus)

KLB, encoding β‐Klotho, is mutated in patients with congenital hypogonadotropic hypogonadism

Xu, C., Messina, A., Somm, E., Miraoui, H., Kinnunen, T., Acierno, J., Niederländer, N. J., Bouilly, J., Dwyer, A. A., Sidis, Y., Cassatella, D., Sykiotis, G. P., Quinton, R., De Geyter, C., Dirlewanger, M., Schwitzgebel, V., Cole, T. R., Toogood, A. A., Kirk, J. M., Plummer, L. & 6 others, Albrecht, U., Crowley, W. F., Mohammadi, M., Tena‐sempere, M., Prevot, V. & Pitteloud, N., 1 Aug 2017, In : EMBO Molecular Medicine. 9, 10, p. 1379-1397 9 p.

Research output: Contribution to journal › Article

Open Access

Receptor, Fibroblast Growth Factor, Type 1

Hypogonadism

Hormones

Mutation

Neurons

22 Citations (Scopus)