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Personal profile

Biography

I did my PhD at the Institute of Biotechnology and University of Helsinki, Finland, combining developmental neurobiology and glycobiology to study mechanisms of syndecan-3 mediated neurite outgrowth using mammalian models. As an EMBO Long-Term Fellow and subsequently as a Wellcome Trust Advanced Training Fellow at the University of Birmingham, I translated my cell biology and biochemistry background into the use of the nematode C. elegans as a genetic model organism. As an MRC New Investigator at the University of Liverpool, my research interest into glycosylated membrane proteins expanded from heparan sulphate proteoglycans to fibroblast growth factor (FGF) and Klotho signalling in development and metabolic physiology. In December 2012 I was appointed as a Senior Lecturer at the University of Huddersfield.

Research Expertise and Interests

  • Glycosylation as a regulator of development
  • Metabolic physiology and disease

Research Degree Supervision

Click Here to see all postgraduate research opportunities with Dr Tarja Kinnunen

Fingerprint Dive into the research topics where Tarja Kinnunen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Heparitin Sulfate Medicine & Life Sciences
Caenorhabditis elegans Medicine & Life Sciences
Fibroblast Growth Factor Receptors Medicine & Life Sciences
Heparan Sulfate Proteoglycans Medicine & Life Sciences
Glypicans Medicine & Life Sciences
Cell Movement Medicine & Life Sciences
Syndecans Medicine & Life Sciences
Sulfotransferases Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2015 2017

Research Output 2003 2017

20 Citations (Scopus)

KLB, encoding β‐Klotho, is mutated in patients with congenital hypogonadotropic hypogonadism

Xu, C., Messina, A., Somm, E., Miraoui, H., Kinnunen, T., Acierno, J., Niederländer, N. J., Bouilly, J., Dwyer, A. A., Sidis, Y., Cassatella, D., Sykiotis, G. P., Quinton, R., De Geyter, C., Dirlewanger, M., Schwitzgebel, V., Cole, T. R., Toogood, A. A., Kirk, J. M., Plummer, L. & 6 others, Albrecht, U., Crowley, W. F., Mohammadi, M., Tena‐sempere, M., Prevot, V. & Pitteloud, N., 1 Aug 2017, In : EMBO Molecular Medicine. 9, 10, p. 1379-1397 9 p.

Research output: Contribution to journalArticle

Open Access
Receptor, Fibroblast Growth Factor, Type 1
Hypogonadism
Hormones
Mutation
Neurons
22 Citations (Scopus)

Fibroblast growth factors as tissue repair and regeneration therapeutics

Nunes, Q. M., Li, Y., Sun, C., Kinnunen, T. K. & Fernig, D. G., 12 Jan 2016, In : PeerJ. 31 p., e1535.

Research output: Contribution to journalArticle

Open Access
fibroblast growth factors
Fibroblast Growth Factors
tissue repair
Regeneration
Repair
12 Citations (Scopus)
Open Access
Heparan Sulfate Proteoglycans
Heparitin Sulfate
neurodevelopment
proteoglycans
Caenorhabditis elegans
13 Citations (Scopus)

The Cooperation of FGF receptor and Klotho is involved in Excretory Canal Development and Regulation of Metabolic Homeostasis in Caenorhabditis elegans

Polanska, U. M., Edwards, E., Fernig, D. G. & Kinnunen, T. K., 18 Feb 2011, In : Journal of Biological Chemistry. 286, 7, p. 5657-5666 10 p.

Research output: Contribution to journalArticle

Open Access
Fibroblast Growth Factor Receptors
Caenorhabditis elegans
Canals
Homeostasis
Aging of materials
31 Citations (Scopus)

Extracellular Interactome of the FGF Receptor-Ligand System: Complexities and the Relative Simplicity of the Worm

Polanska, U. M., Fernig, D. G. & Kinnunen, T., Feb 2009, In : Developmental Dynamics. 238, 2, p. 277-293 17 p.

Research output: Contribution to journalReview article

Fibroblast Growth Factor Receptors
Ligands
Neural Cell Adhesion Molecules
Heparan Sulfate Proteoglycans
Growth Factor Receptors

Activities 2001 2019

Exploring the role of cell signalling co-factor, Klotho, in longevity and healthy lifespan

Tarja Kinnunen (Speaker)
5 Sep 2019

Activity: Talk or presentation typesInvited talk

PhD viva at the School of Biological Sciences University of East Anglia

Tarja Kinnunen (Examiner)
4 Sep 2019

Activity: Examination typesPhD Examination

Scientific Reports (Journal)

Tarja Kinnunen (Reviewer)
2019 → …

Activity: Publication peer-review and editorial work typesPublication Peer-review

Royal Society of Biology (External organisation)

Tarja Kinnunen (Member)
2019 → …

Activity: Membership typesMembership of a Society or Institute

FGF/HSPG Signalling in C. elegans

Tarja Kinnunen (Speaker)
29 Mar 2018

Activity: Talk or presentation typesInvited talk