β-Sultams - A novel class of serine protease inhibitors

M. Beardsell; P. S. Hinchliffe; J. Matthew Wood; R. C. Wilmouth; C. J. Schofield; M. I. Page

doi:10.1039/b100294p

β-Sultams - A novel class of serine protease inhibitors

M. Beardsell, P. S. Hinchliffe, J. Matthew Wood, R. C. Wilmouth, C. J. Schofield, M. I. Page

School of Applied Sciences

University of Oxford

Research output: Contribution to journal › Article › peer-review

39 Citations (Scopus)

Abstract

N-Benzoyl β-sultam is an irreversible inactivator of elastase by sulfonation of the active site serine.

Original language	English
Pages (from-to)	497-498
Number of pages	2
Journal	Chemical Communications
Issue number	5
Early online date	19 Feb 2001
DOIs	https://doi.org/10.1039/b100294p
Publication status	Published - 7 Mar 2001

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title = "β-Sultams - A novel class of serine protease inhibitors",

abstract = "N-Benzoyl β-sultam is an irreversible inactivator of elastase by sulfonation of the active site serine.",

author = "M. Beardsell and Hinchliffe, \{P. S.\} and Wood, \{J. Matthew\} and Wilmouth, \{R. C.\} and Schofield, \{C. J.\} and Page, \{M. I.\}",

year = "2001",

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doi = "10.1039/b100294p",

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AU - Beardsell, M.

AU - Hinchliffe, P. S.

AU - Wood, J. Matthew

AU - Wilmouth, R. C.

AU - Schofield, C. J.

AU - Page, M. I.

PY - 2001/3/7

Y1 - 2001/3/7

N2 - N-Benzoyl β-sultam is an irreversible inactivator of elastase by sulfonation of the active site serine.

AB - N-Benzoyl β-sultam is an irreversible inactivator of elastase by sulfonation of the active site serine.

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U2 - 10.1039/b100294p

DO - 10.1039/b100294p

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AN - SCOPUS:0035819963

SN - 1359-7345

SP - 497

EP - 498

JO - Chemical Communications

JF - Chemical Communications

IS - 5

ER -

β-Sultams - A novel class of serine protease inhibitors

Abstract

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