A study was conducted to demonstrate the use of 3C-SiC nanocrystals as biological labels in cell imaging, and fluorescence dynamics and surface chemistry of the nanoparticles. The study also demonstrated that 3C-SiC quantum dots, prepared by electrochemical etching with ultrasonic stirring, can be introduced into cells for robust nontoxic biological probes with low photobleaching and long-term stability. The study used nontoxic and highly resistant against photobleaching nanocrystals. The study found that the 3C-SiC nanocrystals can be used for fluorescent biological probes. The study found that the nanoparticles show a nonotonically increasing UV/Vis spectrum with an onset at 2.8eV. The study confirmed that the nanoparticles can be used in multicolor imaging in various biological systems by improving their size monodispersity.