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Author

  • Roger Phillips
2013

Multi-objective multi-drug scheduling schemes for cell cycle specific cancer treatment

Alam, M. S., Hossain, M. A., Algoul, S., Majumader, M. A. A., Al-Mamun, M. A., Sexton, G. & Phillips, R., 11 Nov 2013, In : Computers and Chemical Engineering. 58, p. 14-32 19 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Synthesis and Quantitative Structure-Activity Relationship of Imidazotetrazine Prodrugs with Activity Independent of O6-Methylguanine-DNA-methyltransferase, DNA Mismatch Repair, and p53

Pletsas, D., Garelnabi, E. A. E., Li, L., Phillips, R. M. & Wheelhouse, R. T., 12 Sep 2013, In : Journal of Medicinal Chemistry. 56, 17, p. 7120-7132 13 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2012

A Hybrid Cellular Automaton Model of Solid Tumor Growth and Bioreductive Drug Transport

Kazmi, N., Hossain, M. A. & Phillips, R. M., Nov 2012, In : IEEE/ACM Transactions on Computational Biology and Bioinformatics. 9, 6, p. 1595-1606 12 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Avascular tumour growth dynamics and the constraints of protein binding for drug transportation

Kazmi, N., Hossain, M. A., Phillips, R. M., Al-Mamun, M. A. & Bass, R., 21 Nov 2012, In : Journal of Theoretical Biology. 313, p. 142-152 11 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Characterization of Changes in the Proteome in Different Regions of 3D Multicell Tumor Spheroids

McMahon, K. M., Volpato, M., Chi, H. Y., Musiwaro, P., Poterlowicz, K., Peng, Y., Scally, A. J., Patterson, L. H., Phillips, R. M. & Sutton, C. W., 4 May 2012, In : Journal of Proteome Research. 11, 5, p. 2863-2875 13 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Enhanced cytotoxicity of silver complexes bearing bidentate N-heterocyclic carbene ligands

Monteiro, D. C. F., Phillips, R. M., Crossley, B. D., Fielden, J. & Willans, C. E., 7 Apr 2012, In : Dalton Transactions. 41, 13, p. 3720-3725 6 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)

Minor structural modifications to alchemix influence mechanism of action and pharmacological activity

Abdallah, Q. M. A., Phillips, R. M., Johansson, F., Helleday, T., Cosentino, L., Abdel-Rahman, H., Etzad, J., Wheelhouse, R. T., Kiakos, K., Bingham, J. P., Hartley, J. A., Patterson, L. H. & Pors, K., 1 Jun 2012, In : Biochemical Pharmacology. 83, 11, p. 1514-1522 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Strategy for Imidazotetrazine Prodrugs with Anticancer Activity Independent of MGMT and MMR

Garelnabi, E. A. E., Pletsas, D., Li, L., Kiakos, K., Karodia, N., Hartley, J. A., Phillips, R. M. & Wheelhouse, R. T., 13 Dec 2012, In : ACS Medicinal Chemistry Letters. 3, 12, p. 965-968 4 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Synthesis of iridium and ruthenium complexes with (N,N), (N,O) and (O,O) coordinating bidentate ligands as potential anti-cancer agents

Lucas, S. J., Lord, R. M., Wilson, R. L., Phillips, R. M., Sridharan, V. & McGowan, P. C., 7 Dec 2012, In : Dalton Transactions. 41, 45, p. 13800-13802 3 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)
2011

Corrigendum to "A mathematical model of doxorubicin penetration through multicellular layers" [J. Theor. Biol. 257 (2009) 598-608]

Evans, C. J., Phillips, R. M., Jones, P. F., Loadman, P. M., Sleeman, B. D., Twelves, C. J. & Smye, S. W., 21 Mar 2011, In : Journal of Theoretical Biology. 273, 1, p. 235 1 p.

Research output: Contribution to journalComment/debate

Modelling of tirapazamine effects on solid tumour morphology

Kazmi, N., Hossain, M. A. & Phillips, R. M., 2011, 5th International Conference on Practical Applications of Computational Biology and Bioinformatics (PACBB 2011). Vol. 93. p. 125-132 8 p. (Advances in Intelligent and Soft Computing; vol. 93).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)