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• 2020

  A novel workflow for three-dimensional analysis of tumour cell migration

  Ketchen, S., Rohwedder, A., Knipp, S., Esteves, F., Struve, N., Peckham, M., Ladbury, J., Curd, A., Short, S. & Bruning-Richardson, A., 6 Apr 2020, In: Interface Focus. 10, 2, 6 p., 20190070.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Workflow
  • Tumors
  • Cells
  • Cell Movement
  • Lighting
  1 Citation (Scopus)
• 2018

  A novel 3D high-resolution histopathological image reconstruction method versus common 2D and 3D imaging methodologies for application in cancer spheroid research: Which is better?

  Samarasekara, J., Esteves, F., Curd, A., Hale, M., Magee, D., Treanor, D., Short, S. C. & Bruning-Richardson, A., Nov 2018, In: Neuro-Oncology. 20, S6, p. 271 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  • Computer-Assisted Image Processing
  • MI-192
  • 6-bromoindirubin-3'-oxime
  • Lighting
  • Confocal Microscopy

• A role for FGFR1 in paediatric gliomas

  Egbivwie, N., Warr, T., Humphries, M., Esteves, F., Short, S. C., Cockle, J. V. & Bruning-Richardson, A., Jan 2018, In: Neuro-Oncology. p. 24 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  • Glioma
  • Astrocytoma
  • Cell Movement
  • Pediatrics
  • Fibroblast Growth Factor 2

• Cell adhesion molecule (L1CAM) and phosphorylated fibroblast growth factor receptor 1 (PFGFR1) expression positively correlates with neurological malignancies

  Egbivwie, N., Cook, S., Cockle, J. V., Esteves, F., Short, S. C., Ismail, A., Humphries, M. & Bruning-Richardson, A., Oct 2018, In: Neuro-Oncology. 20, S5, p. 349 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  • Neural Cell Adhesion Molecule L1
  • Receptor, Fibroblast Growth Factor, Type 1
  • Neoplasms
  • Glioma
  • Cell Movement

• Expression analysis of the MCPH1/BRIT1 and BRCA1 tumor suppressor genes and telomerase splice variants in epithelial ovarian cancer

  Alsiary, R., Brownhill, S. C., Brüning-Richardson, A., Hutson, R., Griffin, N., Morrison, E. E., Bond, J., Burchill, S. A. & Bell, S. M., 25 Sep 2018, In: Gene. 672, p. 34-44 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Ovarian Epithelial Carcinoma
  • Telomerase
  • Tumor Suppressor Genes
  • Neoplasms
  4 Citations (Scopus)

• Finding the brake: dissecting the RhoA pathway regulating glioma cell migration

  Taylor, S., Knipp, S., Mavria, G., Ladbury, J. & Bruning-Richardson, A., Jan 2018, In: Neuro-Oncology. 20, S1, p. 21-22 2 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  • CCG 1423
  • Glioma
  • Cell Movement
  • Cell Nucleus Active Transport
  • Cysteine-Rich Protein 61

• Identification of transcriptional targets of GSK3 involved in glioblastoma invasion

  Bruning-Richardson, A., Droop, A., Tams, D., Boissinot, M., Hayes, J., Cheng, V., Cockle, J. V., Ismail, A., Morton, R., Esteves, F., Mittelbronn, M., Lawler, S., Short, S. C. & Mavria, G., Jan 2018, In: Neuro-Oncology. 20, S1, p. 26 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  • Glioblastoma
  • Glycogen Synthase Kinase 3
  • Monomeric GTP-Binding Proteins
  • Genes
  • Fluorescent Antibody Technique

• Selective BCL-X L inhibition promotes apoptosis in combination with MLN8237 in medulloblastoma and pediatric glioblastoma cells

  Levesley, J., Steele, L., Brüning-Richardson, A., Davison, A., Zhou, J., Ding, C., Lawler, S. & Short, S. C., 22 Jan 2018, In: Neuro-Oncology. 20, 2, p. 203-214 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • MLN 8237
  • Medulloblastoma
  • B-Cell Lymphoma
  • Glioblastoma
  • Pediatrics
  7 Citations (Scopus)

• Tackling infiltration in paediatric glioma using histone deacetylase inhibitors, a promising approach

  Jackman, L., Ago, E., Boissinot, M., Grigg, R., Esteves, F., Morton, R., Short, S. C. & Bruning-Richardson, A., Jan 2018, In: Neuro-Oncology. 20, S1, p. 19 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  • Histone Deacetylase Inhibitors
  • Glioma
  • Tubulin
  • Cell Movement
  • Pediatrics
• 2017

  A GSK-3/b-CATENIN/ARHGAP axis regulates glioblastoma invasion

  Bruning-Richardson, A., Mittelbronn, M., Humphries, M., Esteves, F., Boissinot, M., Tams, D., Droop, A., Cockle, J. V., Taylor, S., Morton, R., Ismail, A., Lawler, S., Mavria, G. & Short, S. C., Nov 2017, In: Neuro-Oncology. 19, S6, p. 24 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  Open Access

  • Glycogen Synthase Kinase 3
  • Glioblastoma
  • Catenins
  • Oximes
  • GTP Phosphohydrolases

• ARHGAP gene expression in established glioma cell lines and glioma tumour samples and their association with cell migration

  Taylor, S., Ladbury, J., Short, S. C. & Bruning-Richardson, A., Jan 2017, In: Neuro-Oncology. 19, S1, p. 6 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  Open Access

  • Tumor Cell Line
  • Glioma
  • Cell Movement
  • indirubin
  • Gene Expression

• Characterisation of cell migration in low and high grade paediatric gliomas for assessment of the fibroblast growth factor receptor 1 (FGFR1) as a therapeutic target

  Egbivwie, N., Cockle, J. V., Humphries, M., Ismail, A., Esteves, F., Taylor, C., Morton, R., Warr, T., Short, S. C. & Brüning-Richardson, A., Nov 2017, In: Neuro-Oncology. 19, S6, p. 199-199 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

• HDAC3: The universal target for glioblastoma?

  Salt, E., Humphries, M., Morton, R., Grigg, R. & Bruning-Richardson, A., Nov 2017, In: Neuro-Oncology. 19, p. 231 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  Open Access

  • MI-192
  • Glioblastoma
  • Nestin
  • Tubulin
  • Acetylation

• Oncolytic Herpes Simplex Virus Inhibits Pediatric Brain Tumor Migration and Invasion

  Cockle, J. V., Brüning-Richardson, A., Scott, K. J., Thompson, J., Kottke, T., Morrison, E., Ismail, A., Carcaboso, A. M., Rose, A., Selby, P., Conner, J., Picton, S., Short, S., Vile, R., Melcher, A. & Ilett, E., 16 Jun 2017, In: Molecular Therapy - Oncolytics. 5, p. 75-86 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Oncolytic Viruses
  • Simplexvirus
  • Brain Neoplasms
  • Glioma
  • Pediatrics
  6 Citations (Scopus)

• Selective inhibition of BCL-XL increases sensitivity of pediatric tumour models to the anti-mitotic agent MLN8237

  Levesley, J., Steele, L., Bruning-Richardson, A., Davison, A., Zhou, J., Lawler, S. & Short, S. C., May 2017, In: Neuro-Oncology. 19, S3, p. 94 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  Open Access

  • MLN 8237
  • Pediatrics
  • Medulloblastoma
  • Apoptosis Regulatory Proteins
  • Cell Survival

• Targeting glioma migration with the histone deacetylase inhibitor MI192

  Kaur Bhandal, S., Radcliffe, N., Esteves, F., Morton, R., Grigg, R., Boissinot, M., Short, S. C. & Bruning-Richardson, A., Jan 2017, In: Neuro-Oncology. 19, S1, p. 12 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  Open Access

  • Histone Deacetylase Inhibitors
  • Glioma
  • Tubulin
  • Acetylation
  • Chromatin Assembly and Disassembly
  51 Citations (Scopus)

• The migratory switch: Investigating mesenchymal-amoeboid transition (MAT) in high grade gliomas

  Taylor, S., Knipp, S., Rohwedder, A., Curd, A., Struve, N., Peckham, M., Ladbury, J., Short, S. C. & Bruning-Richardson, A., Nov 2017, In: Neuro-Oncology. 19, S6, p. 22 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  Open Access

  • CCG 1423
  • Glioma
  • Cell Movement
  • Cell Nucleus Active Transport
  • Microscopy
  13 Citations (Scopus)
• 2016

  Contribution of epidemiological knowledge and control strategies in the eradication of rinderpest virus

  Brüning-Richardson, A., Parida, S. & Banyard, A., Oct 2016, Mononegaviruses of Veterinary Importance Vol II. Munir, M. (ed.). CABI

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

• Oncolytic herpes simplex virus: An anti-invasive therapeutic strategy for paediatric high grade glioma and diffuse intrinsic pontine glioma

  Cockle, J. V., Ilett, E., Bruning-Richardson, A., Thompson, J., Kottke, T., Scott, K., Morrison, E. E., Ismail, A., Rose, A., Picton, S., Vile, R., Selby, P. J., Short, S. C. & Melcher, A., Jun 2016, In: Neuro-Oncology. 18, S3, p. 49 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  Open Access

  • Oncolytic Viruses
  • Simplexvirus
  • Glioma
  • Pediatrics
  • Therapeutics

• Rinderpest Virus

  Brüning-Richardson, A., Aug 2016, Molecular Detection of Animal Viral Pathogens. Liu, D. (ed.). CRC Press / Taylor Francis, p. 485-494 10 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
• 2015

  Cell migration in paediatric glioma; characterisation and potential therapeutic targeting

  Cockle, J. V., Picton, S., Levesley, J., Ilett, E., Carcaboso, A. M., Short, S., Steel, L. P., Melcher, A., Lawler, S. E. & Brüning-Richardson, A., 17 Feb 2015, In: British Journal of Cancer. 112, 4, p. 693-703 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Glioma
  • Cell Movement
  • Pediatrics
  • Lithium Chloride
  • Oximes
  15 Citations (Scopus)

• High-content analysis of tumour cell invasion in three-dimensional spheroid assays

  Cheng, V., Esteves, F., Chakrabarty, A., Cockle, J., Short, S. & Brüning-Richardson, A., 14 Jun 2015, In: Oncoscience. 2, 6, p. 596-606 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neoplasms
  • Glioma
  • Cellular Spheroids
  • Pharmaceutical Preparations
  • Fluorescent Antibody Technique
  16 Citations (Scopus)

• Novel immunohistochemical methodology for the investigation of stem cell-like subpopulations in glioma spheroids and migratory cells

  Cheng, V., Estevez, F., Chakrabarty, A., Cockle, J. V., Short, S. C. & Bruning-Richardson, A., Nov 2015, In: Neuro-Oncology. 17, S8, p. 3 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  Open Access

  • Glioma
  • Stem Cells
  • Pharmaceutical Preparations
  • Immunohistochemistry
  • indirubin

• Oncolytic herpes simplex virus inhibits paediatric high grade glioma and diffuse intrinsic pontine glioma migration and invasion: Mechanism and potential for clinical application

  Cockle, J. V., Ilett, E., Bruning-Richardson, A., Scott, K., Picton, S., Short, S. C. & Melcher, A., Nov 2015, In: Neuro-Oncology. 17, S8, p. 16 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  Open Access

  • Oncolytic Viruses
  • Simplexvirus
  • Glioma
  • Pediatrics
  • Glycogen Synthase Kinase 3
• 2014

  Deregulation of microcephalin and ASPM expression are correlated with epithelial ovarian cancer progression

  Alsiary, R., Brüning-Richardson, A., Bond, J., Morrison, E. E., Wilkinson, N. & Bell, S. M., 15 May 2014, In: PLoS One. 9, 5, e97059.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • ovarian neoplasms
  • Deregulation
  • Microcephaly
  • Ovarian Epithelial Carcinoma
  • Tumors
  19 Citations (Scopus)

• Evaluating the effects of oncolytic Herpes Simplex Virus (SEPREHVIR) on paediatric high grade glioma viability, migration and invasion: Potential for clinical application

  Cockle, J. V., Ilett, E., Scott, K., Bruning-Richardson, A., Picton, S., Short, S. C. & Melcher, A., Dec 2014, In: Human Gene Therapy. 25, 12, 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  • Oncolytic Viruses
  • Simplexvirus
  • Glioma
  • Pediatrics
  • Cell Line

• Glycogen synthase kinase inhibitors reduce 3D migration of patient derived glioblastoma multiforme stem cells

  Tams, D., Murray, C., Barry, S. T., Lawler, S. & Bruning-Richardson, A., Oct 2014, In: Neuro-Oncology. 16, S6, p. 22 1 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  Open Access

  • Glycogen Synthase Kinases
  • Glioblastoma
  • AZD2858
  • Stem Cells
  • Glycogen Synthase Kinase 3

• High resolution three-dimensional histological reconstruction of glioma spheroids and application in research

  Bruning-Richardson, A., Roberts, N., Crellin, D., Treanor, D. & Short, S. C., Nov 2014, In: Neuro-Oncology. 16, S5, p. 139-140 2 p.

  Research output: Contribution to journal › Meeting Abstract › peer-review

  Open Access

  • Glioma
  • Collagen
  • Software
  • Pharmaceutical Preparations
  • Computer-Assisted Image Processing

• Rinderpest Virus

  Banyard, A., Bruning, A. & Parida, S., 8 Apr 2014, Manual of security sensitive microbes and toxins. Liu, D. (ed.). CRC Press / Taylor Francis, p. 715-726 12 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
• 2013

  Bluetongue virus infection induces aberrant mitosis in mammalian cells

  Shaw, A. E., Brüning-Richardson, A., Morrison, E. E., Bond, J., Simpson, J., Ross-Smith, N., Alpar, O., Mertens, P. P. C. & Monaghan, P., 30 Oct 2013, In: Virology Journal. 10, 319.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Bluetongue virus
  • Mitosis
  • Virus Diseases
  • bluetongue virus NS1 protein
  • Centrosome
  3 Citations (Scopus)

• Rinderpest Virus

  Bruning, A. & Banyard, A., 26 Nov 2013, Mononegaviruses of veterinary importance: Volume 1 Pathobiology and Molecular Diagnosis. Munir, M. (ed.). CABI Publishing

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
• 2012

  NuMA overexpression in epithelial ovarian cancer

  Brüning-Richardson, A., Bond, J., Alsiary, R., Richardson, J., Cairns, D. A., McCormac, L., Hutson, R., Burns, P. A., Wilkinson, N., Hall, G. D., Morrison, E. E. & Bell, S. M., 14 Jun 2012, In: PLoS One. 7, 6, e38945.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • ovarian neoplasms
  • Ovarian Epithelial Carcinoma
  • Tumors
  • neoplasms
  • aneuploidy
  14 Citations (Scopus)
• 2011

  ASPM and microcephalin expression in epithelial ovarian cancer correlates with tumour grade and survival

  Brüning-Richardson, A., Bond, J., Alsiary, R., Richardson, J., Cairns, D. A., McCormack, L., Hutson, R., Burns, P., Wilkinson, N., Hall, G. D., Morrison, E. E. & Bell, S. M., 10 May 2011, In: British Journal of Cancer. 104, 10, p. 1602-1610 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Microcephaly
  • Ovarian Epithelial Carcinoma
  • Survival
  • Proteins
  • Neoplasms
  43 Citations (Scopus)

• EB1 is required for spindle symmetry in mammalian mitosis

  Brüning-Richardson, A., Langford, K. J., Ruane, P., Lee, T., Askham, J. M. & Morrison, E. E., 21 Dec 2011, In: PLoS One. 6, 12, e28884.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Adenomatous Polyposis Coli Protein
  • Mitosis
  • mitosis
  • Spindle Poles
  • Poles
  18 Citations (Scopus)

• Improvement and development of rapid chromatographic strip-tests for the diagnosis of rinderpest and peste des petits ruminants viruses

  Brüning-Richardson, A., Akerblom, L., Klingeborn, B. & Anderson, J., 1 Jun 2011, In: Journal of Virological Methods. 174, 1-2, p. 42-46 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Rinderpest
  • Rinderpest virus
  • Peste-des-petits-ruminants virus
  • Ruminants
  • Viruses
  12 Citations (Scopus)

• The detection of rinderpest virus RNA extracted from a rapid chromatographic strip-test by RT-PCR

  Brüning-Richardson, A., Barrett, T., Garratt, J. C. & Anderson, J., 1 May 2011, In: Journal of Virological Methods. 173, 2, p. 394-398 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Rinderpest
  • Rinderpest virus
  • Reverse Transcriptase Polymerase Chain Reaction
  • RNA
  • Viral RNA
  1 Citation (Scopus)