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• 2011

  Assessment of gastrointestinal pH, fluid and lymphoid tissue in the guinea pig, rabbit and pig, and implications for their use in drug development

  Merchant, H. A., McConnell, E. L., Liu, F., Ramaswamy, C., Kulkarni, R. P., Basit, A. W. & Murdan, S., 18 Jan 2011, In: European Journal of Pharmaceutical Sciences. 42, 1-2, p. 3-10 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Lymphoid Tissue
  • Drug Development
  • Guinea Pigs
  • Swine
  • Rabbits
  76 Citations (Scopus)

• Does sex matter? The influence of gender on gastrointestinal physiology and drug delivery

  Freire, A. C., Basit, A. W., Choudhary, R., Piong, C. W. & Merchant, H. A., 30 Aug 2011, In: International Journal of Pharmaceutics. 415, 1-2, p. 15-28 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • Gastrointestinal Agents
  • Pharmaceutical Preparations
  • Precision Medicine
  • Drug-Related Side Effects and Adverse Reactions
  • Inborn Genetic Diseases
  103 Citations (Scopus)

• Evolution of a physiological pH 6.8 bicarbonate buffer system: application to the dissolution testing of enteric coated products

  Liu, F., Merchant, H. A., Kulkarni, R. P., Alkademi, M. & Basit, A. W., May 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 78, 1, p. 151-7 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Bicarbonates
  • Buffers
  • hydroxypropyl methylcellulose phthalate
  • hydroxypropylmethylcellulose acetate succinate
  • Phosphates
  72 Citations (Scopus)
• 2014

  Accelerating the dissolution of enteric coatings in the upper small intestine: Evolution of a novel pH 5.6 bicarbonate buffer system to assess drug release

  Varum, F. J. O., Merchant, H., Goyanes, A., Aasi, P., Zboranová, V. & Basit, A. W., 1 Jul 2014, In: International Journal of Pharmaceutics. 468, 1-2, p. 172-177 6 p.

  Research output: Contribution to journal › Article › peer-review

  • L 30
  • Bicarbonates
  • Drug Liberation
  • Buffers
  • Small Intestine
  21 Citations (Scopus)

• Apparatus and method for testing medicaments

  Merchant, H., Frost, J. & Basit, A., 25 Jun 2014, IPC No. GB2509286, Patent No. 2509286, Priority date 2 May 2012, Priority No. 1207677

  Research output: Patent

  Open Access

  File

  • testing
  • methodology
  • drug carriers
  • helium
  • alkalinity

• Influence of ageing on the gastrointestinal environment of the rat and its implications for drug delivery

  Merchant, H., Rabbie, S. C., Varum, F. J. O., Afonso-Pereira, F. & Basit, A. W., 1 Oct 2014, In: European Journal of Pharmaceutical Sciences. 62, p. 76-85 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Solubility
  • Surface Tension
  • Small Intestine
  • Osmolar Concentration
  • Buffers
  11 Citations (Scopus)

• Predicting the gastrointestinal behaviour of modified-release products: Utility of a novel dynamic dissolution test apparatus involving the use of bicarbonate buffers

  Merchant, H., Goyanes, A., Parashar, N. & Basit, A. W., 20 Nov 2014, In: International Journal of Pharmaceutics. 475, 1-2, p. 585-591 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Bicarbonates
  • Buffers
  • Tablets
  • Dosage Forms
  • Prednisolone
  29 Citations (Scopus)

• Pulsatile drug release from electrospun poly(ethylene oxide)–sodium alginate blend nanofibres

  Kaassis, A. Y. A., Young, N., Sano, N., Merchant, H., Yu, D-G., Chatterton, N. P. & Williams, G. R., 14 Mar 2014, In: Journal of Materials Chemistry. 10, p. 1400-1407 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Sodium alginate
  • Polyethylene oxides
  • Nanofibers
  • Ibuprofen
  • Alginates
  21 Citations (Scopus)
• 2015

  Animal Farm: Considerations in Animal Gastrointestinal Physiology and Relevance to Drug Delivery in Humans

  Hatton, G. B., Yadav, V., Basit, A. W. & Merchant, H., 24 Sep 2015, In: Journal of Pharmaceutical Sciences. 104, 9, p. 2747-2776 30 p.

  Research output: Contribution to journal › Article › peer-review

  • Domestic Animals
  • Animals
  • Pharmaceutical Preparations
  • Drug Design
  • Anatomy
  71 Citations (Scopus)

• Gastrointestinal characterisation and drug solubility determination in animals

  Merchant, H., Afonso-Pereira, F., Rabbie, S. C., Youssef, S. A. & Basit, A. W., May 2015, In: Journal of Pharmacy and Pharmacology. 67, 5, p. 630-639 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Gastrointestinal Agents
  • Solubility
  • Prednisolone
  • Animals
  • Surface Tension
  8 Citations (Scopus)

• Gastrointestinal release behaviour of modified-release drug products: Dynamic dissolution testing of mesalazine formulations

  Goyanes, A., Hatton, G. B., Merchant, H. & Basit, A. W., 30 Apr 2015, In: International Journal of Pharmaceutics. 484, 1-2, p. 103-108 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Mesalamine
  • Drug Liberation
  • Bicarbonates
  • Ulcerative Colitis
  • Radionuclide Imaging
  42 Citations (Scopus)
• 2016

  Age-Mediated Changes in the Gastrointestinal Tract

  Merchant, H., Liu, F., Orlu Gul, M. & Basit, A. W., 30 Oct 2016, In: International Journal of Pharmaceutics. 512, 2, p. 382-395 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Gastrointestinal Tract
  • Pharmacokinetics
  • Pharmaceutical Preparations
  • Drug Therapy
  • Intestinal Mucosa
  37 Citations (Scopus)

• A new Open Access Journal for Research, Education and Practice in Pharmacy

  Conway, B. & Merchant, H., 15 Nov 2016, In: British Journal of Pharmacy. 1, 1, p. 1-2 2 p.

  Research output: Contribution to journal › Editorial

  Open Access
• 2017

  Can Diet Help Non-Obese Individuals with Non-Alcoholic Fatty Liver Disease (NAFLD)?

  Merchant, H., 19 Sep 2017, In: Journal of Clinical Medicine. 6, 9, 5 p., 88.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Non-alcoholic Fatty Liver Disease
  • Diet
  • Life Style
  • Body Mass Index
  • Incidental Findings

• Going Natural: Using Polymers from Nature for Gastroresistant Applications

  Cunha Barbosa, J., Conway, B. & Merchant, H., 5 Jul 2017, In: British Journal of Pharmacy. 2, 1, 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Dietary supplements
  • Functional food
  • Natural polymers
  • Industrial applications
  • Polymers

• Impact of Purification on Physicochemical, Surface and Functional Properties of Okra Biopolymer

  Ghori, M. U., Mohammad, M. A., Rudrangi, S. R. S., Fleming, L. T., Merchant, H., Smith, A. M. & Conway, B. R., 1 Oct 2017, In: Food Hydrocolloids. 71, p. 311-320 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Abelmoschus
  • Biopolymers
  • Physicochemical properties
  • Surface Properties
  • okra
  22 Citations (Scopus)

• Maintaining Open Access to High Quality Publications at No Cost to Authors

  Conway, B. & Merchant, H., 13 Nov 2017, In: British Journal of Pharmacy. 2, 1, p. 1-2 2 p.

  Research output: Contribution to journal › Editorial

  Open Access

  • Open access
  • Costs
• 2018

  Physiology of the Gastrointestinal System

  Sauer, J-M. & Merchant, H., 2018, Comprehensive Toxicology. McQueen, C. (ed.). 3rd ed. Elsevier, p. 16-44 29 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Gastrointestinal Tract
  • Mucous Membrane
  • Gastrointestinal Agents
  • Exocrine Pancreas
  • Oropharynx
  1 Citation (Scopus)
• 2019

  Achieving gastroresistance without coating: Formulation of capsule shells from enteric polymers

  Barbosa, J. A. C., Al-Kauraishi, M. M., Smith, A. M., Conway, B. R. & Merchant, H. A., 1 Nov 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 144, p. 174-179 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Capsules
  • Polymers
  • Dosage Forms
  • hydroxypropyl methylcellulose phthalate
  • Drug Liberation
  9 Citations (Scopus)

• Non-steroidal topical formulation for the conditions of the skin

  Merchant, H., Olajide, O. & Farzand, R., 11 Nov 2019, (Submitted) IPO UK, Patent No. 2019464.3 (Application), 10 Dec 2020, Priority date 11 Nov 2019, Priority No. GB1916398.9

  Research output: Patent

  File

• Using zeta potential to study the ionisation behaviour of polymers employed in modified-release dosage forms and estimating their pKa

  Cunha Barbosa, J., Abdelsadig, M., Conway, B. & Merchant, H., 1 Dec 2019, In: International Journal of Pharmaceutics: X. 1, p. 1-11 11 p., 100024.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Dosage Forms
  • Polymers
  • hydroxypropyl methylcellulose phthalate
  • Buffers
  • citrus pectin
  15 Citations (Scopus)