Find Research outputs

Search results

• 2011

  Assessment of gastrointestinal pH, fluid and lymphoid tissue in the guinea pig, rabbit and pig, and implications for their use in drug development

  Merchant, H. A., McConnell, E. L., Liu, F., Ramaswamy, C., Kulkarni, R. P., Basit, A. W. & Murdan, S., 18 Jan 2011, In: European Journal of Pharmaceutical Sciences. 42, 1-2, p. 3-10 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Lymphoid Tissue
  • Drug Development
  • Guinea Pigs
  • Swine
  • Rabbits
  76 Citations (Scopus)

• Does sex matter? The influence of gender on gastrointestinal physiology and drug delivery

  Freire, A. C., Basit, A. W., Choudhary, R., Piong, C. W. & Merchant, H. A., 30 Aug 2011, In: International Journal of Pharmaceutics. 415, 1-2, p. 15-28 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • Gastrointestinal Agents
  • Pharmaceutical Preparations
  • Precision Medicine
  • Drug-Related Side Effects and Adverse Reactions
  • Inborn Genetic Diseases
  103 Citations (Scopus)

• Evolution of a physiological pH 6.8 bicarbonate buffer system: application to the dissolution testing of enteric coated products

  Liu, F., Merchant, H. A., Kulkarni, R. P., Alkademi, M. & Basit, A. W., May 2011, In: European Journal of Pharmaceutics and Biopharmaceutics. 78, 1, p. 151-7 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Bicarbonates
  • Buffers
  • hydroxypropyl methylcellulose phthalate
  • hydroxypropylmethylcellulose acetate succinate
  • Phosphates
  72 Citations (Scopus)
• 2015

  Animal Farm: Considerations in Animal Gastrointestinal Physiology and Relevance to Drug Delivery in Humans

  Hatton, G. B., Yadav, V., Basit, A. W. & Merchant, H., 24 Sep 2015, In: Journal of Pharmaceutical Sciences. 104, 9, p. 2747-2776 30 p.

  Research output: Contribution to journal › Article › peer-review

  • Domestic Animals
  • Animals
  • Pharmaceutical Preparations
  • Drug Design
  • Anatomy
  71 Citations (Scopus)

• Gastrointestinal characterisation and drug solubility determination in animals

  Merchant, H., Afonso-Pereira, F., Rabbie, S. C., Youssef, S. A. & Basit, A. W., May 2015, In: Journal of Pharmacy and Pharmacology. 67, 5, p. 630-639 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Gastrointestinal Agents
  • Solubility
  • Prednisolone
  • Animals
  • Surface Tension
  8 Citations (Scopus)

• Gastrointestinal release behaviour of modified-release drug products: Dynamic dissolution testing of mesalazine formulations

  Goyanes, A., Hatton, G. B., Merchant, H. & Basit, A. W., 30 Apr 2015, In: International Journal of Pharmaceutics. 484, 1-2, p. 103-108 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Mesalamine
  • Drug Liberation
  • Bicarbonates
  • Ulcerative Colitis
  • Radionuclide Imaging
  42 Citations (Scopus)
• 2016

  Age-Mediated Changes in the Gastrointestinal Tract

  Merchant, H., Liu, F., Orlu Gul, M. & Basit, A. W., 30 Oct 2016, In: International Journal of Pharmaceutics. 512, 2, p. 382-395 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Gastrointestinal Tract
  • Pharmacokinetics
  • Pharmaceutical Preparations
  • Drug Therapy
  • Intestinal Mucosa
  37 Citations (Scopus)

• A new Open Access Journal for Research, Education and Practice in Pharmacy

  Conway, B. & Merchant, H., 15 Nov 2016, In: British Journal of Pharmacy. 1, 1, p. 1-2 2 p.

  Research output: Contribution to journal › Editorial

  Open Access
• 2017

  Can Diet Help Non-Obese Individuals with Non-Alcoholic Fatty Liver Disease (NAFLD)?

  Merchant, H., 19 Sep 2017, In: Journal of Clinical Medicine. 6, 9, 5 p., 88.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Non-alcoholic Fatty Liver Disease
  • Diet
  • Life Style
  • Body Mass Index
  • Incidental Findings

• Going Natural: Using Polymers from Nature for Gastroresistant Applications

  Cunha Barbosa, J., Conway, B. & Merchant, H., 5 Jul 2017, In: British Journal of Pharmacy. 2, 1, 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Dietary supplements
  • Functional food
  • Natural polymers
  • Industrial applications
  • Polymers

• Impact of Purification on Physicochemical, Surface and Functional Properties of Okra Biopolymer

  Ghori, M. U., Mohammad, M. A., Rudrangi, S. R. S., Fleming, L. T., Merchant, H., Smith, A. M. & Conway, B. R., 1 Oct 2017, In: Food Hydrocolloids. 71, p. 311-320 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Abelmoschus
  • Biopolymers
  • Physicochemical properties
  • Surface Properties
  • okra
  22 Citations (Scopus)

• Maintaining Open Access to High Quality Publications at No Cost to Authors

  Conway, B. & Merchant, H., 13 Nov 2017, In: British Journal of Pharmacy. 2, 1, p. 1-2 2 p.

  Research output: Contribution to journal › Editorial

  Open Access

  • Open access
  • Costs
• 2018

  Physiology of the Gastrointestinal System

  Sauer, J-M. & Merchant, H., 2018, Comprehensive Toxicology. McQueen, C. (ed.). 3rd ed. Elsevier, p. 16-44 29 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Gastrointestinal Tract
  • Mucous Membrane
  • Gastrointestinal Agents
  • Exocrine Pancreas
  • Oropharynx
  1 Citation (Scopus)
• 2019

  Achieving gastroresistance without coating: Formulation of capsule shells from enteric polymers

  Barbosa, J. A. C., Al-Kauraishi, M. M., Smith, A. M., Conway, B. R. & Merchant, H. A., 1 Nov 2019, In: European Journal of Pharmaceutics and Biopharmaceutics. 144, p. 174-179 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Capsules
  • Polymers
  • Dosage Forms
  • hydroxypropyl methylcellulose phthalate
  • Drug Liberation
  9 Citations (Scopus)

• Non-steroidal topical formulation for the conditions of the skin

  Merchant, H., Olajide, O. & Farzand, R., 11 Nov 2019, (Submitted) IPO UK, Patent No. 2019464.3 (Application), 10 Dec 2020, Priority date 11 Nov 2019, Priority No. GB1916398.9

  Research output: Patent

  File

• Using zeta potential to study the ionisation behaviour of polymers employed in modified-release dosage forms and estimating their pKa

  Cunha Barbosa, J., Abdelsadig, M., Conway, B. & Merchant, H., 1 Dec 2019, In: International Journal of Pharmaceutics: X. 1, p. 1-11 11 p., 100024.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Dosage Forms
  • Polymers
  • hydroxypropyl methylcellulose phthalate
  • Buffers
  • citrus pectin
  15 Citations (Scopus)
• 2020

  Coronavirus may stay with us forever!

  Merchant, H., 11 May 2020, In: The BMJ. 369, 1 p., m1790/rr-6.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  • Coronavirus
  • Pandemics
  • Vaccines
  • SARS Virus
  • Clinical Trials

• CoViD-19: Pharmaceutical care during early disease

  Merchant, H., 29 May 2020, In: The BMJ. 1 p., bmj.m2035/rr-2.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  • Pharmaceutical Services
  • Coronavirus
  • Preprints
  • Quarantine
  • Pandemics

• CoViD-19: An early intervention therapeutic strategy to prevent developing a severe disease as an alternative approach to control the pandemic

  Merchant, H., 23 May 2020, 7 p. (ScienceOpen Preprints).

  Research output: Working paper

  Open Access

  • Pandemics
  • Respiratory System
  • Viruses
  • Vaccines
  • Hospitalization

• CoViD-19 may not end as predicted by the SIR model

  Merchant, H., 2 May 2020, In: The BMJ. 369, 1 p., m1567/rr.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  • Pandemics
  • Singapore
  • Life Cycle Stages
  • Spain
  • Italy

• Dexamethasone and CoViD-19: RECOVERY trial provided invaluable clinical evidence but costed precious lives!

  Merchant, H., Kow, C. S. & Hasan, S. S., 26 Jun 2020, In: The BMJ. 1 p., m2422/rr-10.

  Research output: Contribution to journal › Letter › peer-review

  Open Access
  4 Citations (Scopus)

• Exploration of a New Source of Sustainable Nanomaterial from the Koh-e-Suleiman Mountain Range of Pakistan for Industrial Applications

  Nirwan, J., Farhaj, S., Chaudhary, M. M., Khizer, Z., Hasan, S. S., Angelis-Dimakis, A., Gill, A., Rasheed, H., Abbas, N., Arshad, M. S., Hussain, T., Shahzad, Y., Yousaf, A., Chohan, T. A., Hussain, T., Merchant, H., Akram, M. R., Khan, T. M., Ashraf, M., Conway, B. & 1 others, Ghori, M. U., 17 Jan 2020, In: Scientific Reports. 10, 1, 14 p., 577.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Nanostructured materials
  • nanomaterial
  • Clay
  • mountain range
  • Bentonite

• Hand sanitisers amid CoViD-19: A critical review of alcohol-based products on the market and formulation approaches to respond to increasing demand.

  Beradi, A., Perinelli, D., Merchant, H., Bisharat, L., Basheti, I., Bonacucina, G., Cespi, M. & Palmieri, G., 30 Jun 2020, In: International Journal of Pharmaceutics. 584, 14 p., 119431.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hand Sanitizers
  • Pharmacies
  • Alcohols
  • Sanitation
  • Safety
  28 Citations (Scopus)

• Is it worth the wait? Should Chloroquine or Hydroxychloroquine be allowed for immediate use in CoViD-19?

  Hasan, S. S., Kow, C. S. & Merchant, H., 31 Mar 2020, In: British Journal of Pharmacy. 5, 1, 5 p., 745.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Hydroxychloroquine
  • Coronavirus
  • Chloroquine
  • Pneumonia
  • Pandemics

• Mortality and Disease Severity Among COVID-19 Patients Receiving Renin-Angiotensin System Inhibitors: A Systematic Review and Meta-analysis

  Hasan, S. S., Kow, C. S., Hadi, M. A., Zaidi, S. T. R. & Merchant, H. A., 1 Dec 2020, In: American Journal of Cardiovascular Drugs. 20, 6, p. 571-590 20 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Coronavirus
  • Renin-Angiotensin System
  • Meta-Analysis
  • Systematic Reviews
  • Angiotensin Receptor Antagonists
  1 Citation (Scopus)

• Mortality in COVID-19 patients with acute respiratory distress syndrome and corticosteroids use: a systematic review and meta-analysis

  Hasan, S. S., Capstick, T., Ahmed, R., Kow, C. S., Mazhar, F., Merchant, H. A. & Zaidi, S. T. R., 1 Nov 2020, In: Expert Review of Respiratory Medicine. 14, 11, p. 1149-1163 15 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Coronavirus
  • Adult Respiratory Distress Syndrome
  • Adrenal Cortex Hormones
  • Meta-Analysis
  • Systematic Reviews
  17 Citations (Scopus)

• Natural plant based delivery system: Natural plant-based coatings to improve the delivery and efficacy of nutraceuticals and traditional medicines

  Abdelsadig, M., Ghori, M. U., Conway, B. & Merchant, H., 26 Jun 2020, (Submitted) IPC No. UKPTO, Patent No. GB2009780.4, Priority date 26 Jun 2020, Priority No. GB2009780.4

  Research output: Patent

  File

  • Medicine
  • Dietary supplements
  • Functional food
  • Capsules
  • Coatings

• Pharmacotherapeutic considerations for the management of diabetes mellitus among hospitalized COVID-19 patients

  Hasan, S. S., Kow, C. S., Bain, A., Kavanagh, S., Merchant, H. & Abdul Hadi, M., 15 Oct 2020, In: Expert Opinion on Pharmacotherapy.

  Research output: Contribution to journal › Review article › peer-review

  • Coronavirus
  • Diabetes Mellitus
  • Hypoglycemic Agents
  • Type 2 Diabetes Mellitus
  • Insulin

• RE: Covid-19: trials of four potential treatments to generate “robust data” of what works

  Merchant, H., 4 Apr 2020, In: The BMJ. 1 p., m1206/rr-1.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  • Hope
  • Pandemics
  • Drug Combinations
  • Critical Illness
  • Pharmaceutical Preparations

• Use of corticosteroids in asthma and COPD patients with or without COVID-19

  Hasan, S. S., Capstick, T., Razi Zaidi, S. T., Kow, C. S. & Merchant, H., 1 Aug 2020, In: Respiratory Medicine. 170, 5 p., 106045.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Chronic Obstructive Pulmonary Disease
  • Adrenal Cortex Hormones
  • Asthma
  • Steroids
  • SARS Virus
  3 Citations (Scopus)

• Use of hydroxychloroquine and chloroquine in COVID-19: How good is the quality of randomized controlled trials?

  Mazhar, F., Abdul Hadi, M., Kow, C. S., Marran, A. M. N., Merchant, H. & Hasan, S. S., 1 Dec 2020, In: International Journal of Infectious Diseases. 101, p. 107-120 14 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Hydroxychloroquine
  • Coronavirus
  • Chloroquine
  • Randomized Controlled Trials
  • Clinical Trials
  1 Citation (Scopus)

• Why Pfizer's or Moderna's CoViD-19 vaccine cannot be 95% effective?

  Merchant, H., 30 Nov 2020, In: The BMJ. bmj.m4471/rr-3.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  • Vaccines
  • Phase III Clinical Trials
  • Safety
  • Hope
  • Thinking