A computational model of the LGI1 protein suggests a common binding site for ADAM proteins

Keyphrases

• Binding Site 100%
• LGI1 100%
• LGI1 Gene 100%
• Epileptic Syndromes 100%
• Protein Binding Site 100%
• Two-component Domains 100%
• Functional Model 100%
• Computational Model 100%
• ADAM Proteins 100%
• Protein-protein Interaction 50%
• Binding Protein 50%
• Interacting Proteins 50%
• Molecular Mechanism 50%
• Missense mutation 50%
• Quality Control Mechanism 50%
• Secretion Systems 50%
• Glioma 50%
• In Silico Modeling 50%
• Epilepsy 50%
• Leucine-rich 50%
• Propeller 50%
• Protein Folding 50%
• Three-dimensional (3D) 50%
• Structure Function 50%
• Surface Zone 50%
• Autosomal Dominant 50%
• Functional Surface 50%
• Leucine-rich Repeat Domain 50%
• Cause of Disease 50%
• Structural Units 50%
• Synaptic 50%
• Model Surfaces 50%
• Ion Channel Genes 50%

Biochemistry, Genetics and Molecular Biology

• Binding Site 100%
• LGI1 100%
• Binding Protein 75%
• Protein-Protein Interaction 25%
• Missense Mutation 25%
• Protein Folding 25%
• Leucine 25%
• Ion Channel 25%
• Autosomal Dominant Inheritance 25%
• Secretion (Process) 25%
• Leucine-Rich Repeat 25%
• Structure Activity Relation 25%
• Quality Control 25%

Neuroscience

• ADAM Protein 100%
• Binding Site 100%
• Protein Binding 100%
• Leucine 66%
• Protein Folding 33%
• Missense Mutation 33%
• Ion Channel 33%
• Protein-Protein Interaction 33%