A new and simple method for the synthesis of highly functionalised pyrrolizidines, indolizidines and pyrroloazepines

Paul A. O'Gorman; Ting Chen; Hannah E. Cross; Saleena Naeem; Arnaud Pitard; M. Ilyas Qamar; Karl Hemming

doi:10.1016/j.tetlet.2008.08.061

A new and simple method for the synthesis of highly functionalised pyrrolizidines, indolizidines and pyrroloazepines

Paul A. O'Gorman, Ting Chen, Hannah E. Cross, Saleena Naeem, Arnaud Pitard, M. Ilyas Qamar, Karl Hemming

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

The reaction of 5-, 6- and 7-membered cyclic thioimidates with cyclopropenones gives access to highly functionalised pyrrolizidines, indolizidines and pyrroloazepines via a formal [3+2] cycloaddition process.

Original language	English
Pages (from-to)	6316-6319
Number of pages	4
Journal	Tetrahedron Letters
Volume	49
Issue number	44
Early online date	23 Aug 2008
DOIs	https://doi.org/10.1016/j.tetlet.2008.08.061
Publication status	Published - 27 Oct 2008

Access to Document

10.1016/j.tetlet.2008.08.061Licence: Unspecified

Cite this

@article{80581a6367f94298931fa354fc3ddb0b,

title = "A new and simple method for the synthesis of highly functionalised pyrrolizidines, indolizidines and pyrroloazepines",

abstract = "The reaction of 5-, 6- and 7-membered cyclic thioimidates with cyclopropenones gives access to highly functionalised pyrrolizidines, indolizidines and pyrroloazepines via a formal [3+2] cycloaddition process.",

keywords = "Alkaloid, Cyclopropenone, Indolizidine, Pyrrolizidine",

author = "O'Gorman, \{Paul A.\} and Ting Chen and Cross, \{Hannah E.\} and Saleena Naeem and Arnaud Pitard and Qamar, \{M. Ilyas\} and Karl Hemming",

year = "2008",

month = oct,

day = "27",

doi = "10.1016/j.tetlet.2008.08.061",

language = "English",

volume = "49",

pages = "6316--6319",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Limited",

number = "44",

}

TY - JOUR

T1 - A new and simple method for the synthesis of highly functionalised pyrrolizidines, indolizidines and pyrroloazepines

AU - O'Gorman, Paul A.

AU - Chen, Ting

AU - Cross, Hannah E.

AU - Naeem, Saleena

AU - Pitard, Arnaud

AU - Qamar, M. Ilyas

AU - Hemming, Karl

PY - 2008/10/27

Y1 - 2008/10/27

N2 - The reaction of 5-, 6- and 7-membered cyclic thioimidates with cyclopropenones gives access to highly functionalised pyrrolizidines, indolizidines and pyrroloazepines via a formal [3+2] cycloaddition process.

AB - The reaction of 5-, 6- and 7-membered cyclic thioimidates with cyclopropenones gives access to highly functionalised pyrrolizidines, indolizidines and pyrroloazepines via a formal [3+2] cycloaddition process.

KW - Alkaloid

KW - Cyclopropenone

KW - Indolizidine

KW - Pyrrolizidine

UR - https://www.scopus.com/pages/publications/51549114837

U2 - 10.1016/j.tetlet.2008.08.061

DO - 10.1016/j.tetlet.2008.08.061

M3 - Article

AN - SCOPUS:51549114837

SN - 0040-4039

VL - 49

SP - 6316

EP - 6319

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 44

ER -

A new and simple method for the synthesis of highly functionalised pyrrolizidines, indolizidines and pyrroloazepines

Abstract

Access to Document

Other files and links

Fingerprint

Cite this