A new approach to retinoids via organometallic addition to pyrylium salts

Karl Hemming, Edna Faria De Medeiros, Richard J.K. Taylor

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

A new, concise approach to retinoid synthesis is described based on organometallic addition to pyrylium salts; the use of 4-methylpyrylium tetrafluoroborate giving 13Z-retinal which is readily isomerised to retinal itself; the corresponding unsubstituted and 4-cyclohexyl pyrylium salts are transformed into 13-H and 13-cyclohexyl retinal analogues.

LanguageEnglish
Pages2623-2624
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number22
DOIs
Publication statusPublished - 1 Dec 1994
Externally publishedYes

Fingerprint

Retinoids
Organometallics
Salts

Cite this

@article{bf8b4686cdf1445b9f6cf2b7514fe373,
title = "A new approach to retinoids via organometallic addition to pyrylium salts",
abstract = "A new, concise approach to retinoid synthesis is described based on organometallic addition to pyrylium salts; the use of 4-methylpyrylium tetrafluoroborate giving 13Z-retinal which is readily isomerised to retinal itself; the corresponding unsubstituted and 4-cyclohexyl pyrylium salts are transformed into 13-H and 13-cyclohexyl retinal analogues.",
author = "Karl Hemming and {De Medeiros}, {Edna Faria} and Taylor, {Richard J.K.}",
year = "1994",
month = "12",
day = "1",
doi = "10.1039/C39940002623",
language = "English",
pages = "2623--2624",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
number = "22",

}

A new approach to retinoids via organometallic addition to pyrylium salts. / Hemming, Karl; De Medeiros, Edna Faria; Taylor, Richard J.K.

In: Journal of the Chemical Society, Chemical Communications, No. 22, 01.12.1994, p. 2623-2624.

Research output: Contribution to journalArticle

TY - JOUR

T1 - A new approach to retinoids via organometallic addition to pyrylium salts

AU - Hemming, Karl

AU - De Medeiros, Edna Faria

AU - Taylor, Richard J.K.

PY - 1994/12/1

Y1 - 1994/12/1

N2 - A new, concise approach to retinoid synthesis is described based on organometallic addition to pyrylium salts; the use of 4-methylpyrylium tetrafluoroborate giving 13Z-retinal which is readily isomerised to retinal itself; the corresponding unsubstituted and 4-cyclohexyl pyrylium salts are transformed into 13-H and 13-cyclohexyl retinal analogues.

AB - A new, concise approach to retinoid synthesis is described based on organometallic addition to pyrylium salts; the use of 4-methylpyrylium tetrafluoroborate giving 13Z-retinal which is readily isomerised to retinal itself; the corresponding unsubstituted and 4-cyclohexyl pyrylium salts are transformed into 13-H and 13-cyclohexyl retinal analogues.

UR - http://www.scopus.com/inward/record.url?scp=0028079703&partnerID=8YFLogxK

U2 - 10.1039/C39940002623

DO - 10.1039/C39940002623

M3 - Article

SP - 2623

EP - 2624

JO - Chemical Communications

T2 - Chemical Communications

JF - Chemical Communications

SN - 1359-7345

IS - 22

ER -