A new approach to retinoids via organometallic addition to pyrylium salts

Karl Hemming, Edna Faria De Medeiros, Richard J.K. Taylor

Research output: Contribution to journalArticle

4 Citations (Scopus)


A new, concise approach to retinoid synthesis is described based on organometallic addition to pyrylium salts; the use of 4-methylpyrylium tetrafluoroborate giving 13Z-retinal which is readily isomerised to retinal itself; the corresponding unsubstituted and 4-cyclohexyl pyrylium salts are transformed into 13-H and 13-cyclohexyl retinal analogues.

Original languageEnglish
Pages (from-to)2623-2624
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number22
Publication statusPublished - 1 Dec 1994
Externally publishedYes


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