A new approach to the synthesis of non-racemic isoindolin-1-one derivatives

Steven M. Allin, Christopher J. Northfield, Michael I. Page, Alexandra M.Z. Slawin

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

A new approach for the synthesis of non-racemic 3-substituted isoindolin-1-one targets has been developed through application of a tricyclic γ-lactam substrate as an N-acyliminium ion precursor.

Original languageEnglish
Pages (from-to)141-142
Number of pages2
JournalTetrahedron Letters
Volume40
Issue number1
DOIs
Publication statusPublished - 1 Jan 1999

Fingerprint

Lactams
Ions
Derivatives
Substrates

Cite this

Allin, S. M., Northfield, C. J., Page, M. I., & Slawin, A. M. Z. (1999). A new approach to the synthesis of non-racemic isoindolin-1-one derivatives. Tetrahedron Letters, 40(1), 141-142. https://doi.org/10.1016/S0040-4039(98)80041-5
Allin, Steven M. ; Northfield, Christopher J. ; Page, Michael I. ; Slawin, Alexandra M.Z. / A new approach to the synthesis of non-racemic isoindolin-1-one derivatives. In: Tetrahedron Letters. 1999 ; Vol. 40, No. 1. pp. 141-142.
@article{8b72495bcefd4ced9c5ea52458304b52,
title = "A new approach to the synthesis of non-racemic isoindolin-1-one derivatives",
abstract = "A new approach for the synthesis of non-racemic 3-substituted isoindolin-1-one targets has been developed through application of a tricyclic γ-lactam substrate as an N-acyliminium ion precursor.",
keywords = "Aminals, Amino alcohols, Nitrogen heterocycles, Stereocontrol, Transition states",
author = "Allin, {Steven M.} and Northfield, {Christopher J.} and Page, {Michael I.} and Slawin, {Alexandra M.Z.}",
year = "1999",
month = "1",
day = "1",
doi = "10.1016/S0040-4039(98)80041-5",
language = "English",
volume = "40",
pages = "141--142",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "1",

}

A new approach to the synthesis of non-racemic isoindolin-1-one derivatives. / Allin, Steven M.; Northfield, Christopher J.; Page, Michael I.; Slawin, Alexandra M.Z.

In: Tetrahedron Letters, Vol. 40, No. 1, 01.01.1999, p. 141-142.

Research output: Contribution to journalArticle

TY - JOUR

T1 - A new approach to the synthesis of non-racemic isoindolin-1-one derivatives

AU - Allin, Steven M.

AU - Northfield, Christopher J.

AU - Page, Michael I.

AU - Slawin, Alexandra M.Z.

PY - 1999/1/1

Y1 - 1999/1/1

N2 - A new approach for the synthesis of non-racemic 3-substituted isoindolin-1-one targets has been developed through application of a tricyclic γ-lactam substrate as an N-acyliminium ion precursor.

AB - A new approach for the synthesis of non-racemic 3-substituted isoindolin-1-one targets has been developed through application of a tricyclic γ-lactam substrate as an N-acyliminium ion precursor.

KW - Aminals

KW - Amino alcohols

KW - Nitrogen heterocycles

KW - Stereocontrol

KW - Transition states

UR - http://www.scopus.com/inward/record.url?scp=0032889914&partnerID=8YFLogxK

U2 - 10.1016/S0040-4039(98)80041-5

DO - 10.1016/S0040-4039(98)80041-5

M3 - Article

VL - 40

SP - 141

EP - 142

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 1

ER -