A new approach to the synthesis of non-racemic isoindolin-1-one derivatives

Steven M. Allin; Christopher J. Northfield; Michael I. Page; Alexandra M.Z. Slawin

doi:10.1016/S0040-4039(98)80041-5

A new approach to the synthesis of non-racemic isoindolin-1-one derivatives

Steven M. Allin, Christopher J. Northfield, Michael I. Page, Alexandra M.Z. Slawin

Loughborough University

Research output: Contribution to journal › Article › peer-review

35 Citations (Scopus)

Abstract

A new approach for the synthesis of non-racemic 3-substituted isoindolin-1-one targets has been developed through application of a tricyclic γ-lactam substrate as an N-acyliminium ion precursor.

Original language	English
Pages (from-to)	141-142
Number of pages	2
Journal	Tetrahedron Letters
Volume	40
Issue number	1
DOIs	https://doi.org/10.1016/S0040-4039(98)80041-5
Publication status	Published - 1 Jan 1999

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title = "A new approach to the synthesis of non-racemic isoindolin-1-one derivatives",

abstract = "A new approach for the synthesis of non-racemic 3-substituted isoindolin-1-one targets has been developed through application of a tricyclic γ-lactam substrate as an N-acyliminium ion precursor.",

keywords = "Aminals, Amino alcohols, Nitrogen heterocycles, Stereocontrol, Transition states",

author = "Allin, \{Steven M.\} and Northfield, \{Christopher J.\} and Page, \{Michael I.\} and Slawin, \{Alexandra M.Z.\}",

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AU - Allin, Steven M.

AU - Northfield, Christopher J.

AU - Page, Michael I.

AU - Slawin, Alexandra M.Z.

PY - 1999/1/1

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N2 - A new approach for the synthesis of non-racemic 3-substituted isoindolin-1-one targets has been developed through application of a tricyclic γ-lactam substrate as an N-acyliminium ion precursor.

AB - A new approach for the synthesis of non-racemic 3-substituted isoindolin-1-one targets has been developed through application of a tricyclic γ-lactam substrate as an N-acyliminium ion precursor.

KW - Aminals

KW - Amino alcohols

KW - Nitrogen heterocycles

KW - Stereocontrol

KW - Transition states

UR - https://www.scopus.com/pages/publications/0032889914

U2 - 10.1016/S0040-4039(98)80041-5

DO - 10.1016/S0040-4039(98)80041-5

M3 - Article

AN - SCOPUS:0032889914

SN - 0040-4039

VL - 40

SP - 141

EP - 142

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 1

ER -

A new approach to the synthesis of non-racemic isoindolin-1-one derivatives

Abstract

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