A one-pot synthesis of α-formyl-α-allylacetates via nucleophilic catalysis

William Chung, Petra Lindovska, Jason E. Camp

Research output: Contribution to journalArticle

7 Citations (Scopus)


A step-economical one-pot nucleophilic catalysis/thermal Claisen-rearrangement protocol for the direct synthesis of α-formyl- α-allylacetates from allylic alcohols and activated alkynes has been developed. The product α-formyl-α-allylacetates were further reacted in situ to give either protected enol ethers or β-hydroxy-4-pentenoates.

Original languageEnglish
Pages (from-to)6785-6787
Number of pages3
JournalTetrahedron Letters
Issue number50
Early online date14 Oct 2011
Publication statusPublished - 14 Dec 2011
Externally publishedYes


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