A one-pot synthesis of α-formyl-α-allylacetates via nucleophilic catalysis

William Chung, Petra Lindovska, Jason E. Camp

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

A step-economical one-pot nucleophilic catalysis/thermal Claisen-rearrangement protocol for the direct synthesis of α-formyl- α-allylacetates from allylic alcohols and activated alkynes has been developed. The product α-formyl-α-allylacetates were further reacted in situ to give either protected enol ethers or β-hydroxy-4-pentenoates.

LanguageEnglish
Pages6785-6787
Number of pages3
JournalTetrahedron Letters
Volume52
Issue number50
Early online date14 Oct 2011
DOIs
Publication statusPublished - 14 Dec 2011
Externally publishedYes

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Alkynes
Ethers
Catalysis
Hot Temperature
allyl alcohol
4-pentenoic acid

Cite this

Chung, William ; Lindovska, Petra ; Camp, Jason E. / A one-pot synthesis of α-formyl-α-allylacetates via nucleophilic catalysis. In: Tetrahedron Letters. 2011 ; Vol. 52, No. 50. pp. 6785-6787.
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A one-pot synthesis of α-formyl-α-allylacetates via nucleophilic catalysis. / Chung, William; Lindovska, Petra; Camp, Jason E.

In: Tetrahedron Letters, Vol. 52, No. 50, 14.12.2011, p. 6785-6787.

Research output: Contribution to journalArticle

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