TY - JOUR
T1 - A Reversible Inhibitor of P-Lactamase I from Bacillus cereus
AU - Jones, Mark
AU - Buckwell, Stephen C.
AU - Page, Michael I.
AU - Wrigglesworth, Roger
PY - 1989/1
Y1 - 1989/1
N2 - α-Methyl (3S,5R,6R)benzylpenicilloate is a reversible competitive inhibitor of β-lactamase l from Bacillus cereus; the inhibition constant Ki is 6.38 × 10-4M and is independent of pH between pH 5 and 8 which is compatible with binding of the free base form of the thiazolidine residue to the enzyme.
AB - α-Methyl (3S,5R,6R)benzylpenicilloate is a reversible competitive inhibitor of β-lactamase l from Bacillus cereus; the inhibition constant Ki is 6.38 × 10-4M and is independent of pH between pH 5 and 8 which is compatible with binding of the free base form of the thiazolidine residue to the enzyme.
UR - http://www.scopus.com/inward/record.url?scp=0024576827&partnerID=8YFLogxK
U2 - 10.1039/C39890000070
DO - 10.1039/C39890000070
M3 - Article
AN - SCOPUS:0024576827
SP - 70
EP - 71
JO - Chemical Communications
JF - Chemical Communications
SN - 1359-7345
IS - 2
ER -