A Reversible Inhibitor of P-Lactamase I from Bacillus cereus

Mark Jones, Stephen C. Buckwell, Michael I. Page, Roger Wrigglesworth

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

α-Methyl (3S,5R,6R)benzylpenicilloate is a reversible competitive inhibitor of β-lactamase l from Bacillus cereus; the inhibition constant Ki is 6.38 × 10-4M and is independent of pH between pH 5 and 8 which is compatible with binding of the free base form of the thiazolidine residue to the enzyme.

Original languageEnglish
Pages (from-to)70-71
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number2
DOIs
Publication statusPublished - Jan 1989

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Thiazolidines
Bacillus cereus
Enzymes

Cite this

Jones, Mark ; Buckwell, Stephen C. ; Page, Michael I. ; Wrigglesworth, Roger. / A Reversible Inhibitor of P-Lactamase I from Bacillus cereus. In: Journal of the Chemical Society, Chemical Communications. 1989 ; No. 2. pp. 70-71.
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A Reversible Inhibitor of P-Lactamase I from Bacillus cereus. / Jones, Mark; Buckwell, Stephen C.; Page, Michael I.; Wrigglesworth, Roger.

In: Journal of the Chemical Society, Chemical Communications, No. 2, 01.1989, p. 70-71.

Research output: Contribution to journalArticle

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