A Systematic Review and Meta-analysis of Psychosocial Interventions to Reduce Drug and Sexual Blood Borne Virus Risk Behaviours Among People Who Inject Drugs

Gail Gilchrist, Davina Swan, Kideshini Widyaratna, Julia Elena Marquez-Arrico, Elizabeth Hughes, Noreen Dadirai Mdege, Marrissa Martyn-St James, Judit Tirado-Munoz

Research output: Contribution to journalReview article

10 Citations (Scopus)

Abstract

Opiate substitution treatment and needle exchanges have reduced blood borne virus (BBV) transmission among people who inject drugs (PWID). Psychosocial interventions could further prevent BBV. A systematic review and meta-analysis examined whether psychosocial interventions (e.g. CBT, skills training) compared to control interventions reduced BBV risk behaviours among PWID. 32 and 24 randomized control trials (2000-May 2015 in MEDLINE, PsycINFO, CINAHL, Cochrane Collaboration and Clinical trials, with an update in MEDLINE to December 2016) were included in the review and meta-analysis respectively. Psychosocial interventions appear to reduce: sharing of needles/syringes compared to education/information (SMD −0.52; 95% CI −1.02 to −0.03; I2 = 10%; p = 0.04) or HIV testing/counselling (SMD −0.24; 95% CI −0.44 to −0.03; I2 = 0%; p = 0.02); sharing of other injecting paraphernalia (SMD −0.24; 95% CI −0.42 to −0.06; I2 = 0%; p < 0.01) and unprotected sex (SMD −0.44; 95% CI −0.86 to −0.01; I2 = 79%; p = 0.04) compared to interventions of a lesser time/intensity, however, moderate to high heterogeneity was reported. Such interventions could be included with other harm reduction approaches to prevent BBV transmission among PWID.

Original languageEnglish
Pages (from-to)1791-1811
Number of pages21
JournalAIDS and Behavior
Volume21
Issue number7
Early online date1 Apr 2017
DOIs
Publication statusPublished - 1 Jul 2017

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Risk-Taking
Meta-Analysis
Needle Sharing
Viruses
MEDLINE
Pharmaceutical Preparations
Opiate Substitution Treatment
Harm Reduction
Unsafe Sex
Needles
Counseling
Clinical Trials
HIV
Education

Cite this

Gilchrist, Gail ; Swan, Davina ; Widyaratna, Kideshini ; Marquez-Arrico, Julia Elena ; Hughes, Elizabeth ; Mdege, Noreen Dadirai ; Martyn-St James, Marrissa ; Tirado-Munoz, Judit. / A Systematic Review and Meta-analysis of Psychosocial Interventions to Reduce Drug and Sexual Blood Borne Virus Risk Behaviours Among People Who Inject Drugs. In: AIDS and Behavior. 2017 ; Vol. 21, No. 7. pp. 1791-1811.
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abstract = "Opiate substitution treatment and needle exchanges have reduced blood borne virus (BBV) transmission among people who inject drugs (PWID). Psychosocial interventions could further prevent BBV. A systematic review and meta-analysis examined whether psychosocial interventions (e.g. CBT, skills training) compared to control interventions reduced BBV risk behaviours among PWID. 32 and 24 randomized control trials (2000-May 2015 in MEDLINE, PsycINFO, CINAHL, Cochrane Collaboration and Clinical trials, with an update in MEDLINE to December 2016) were included in the review and meta-analysis respectively. Psychosocial interventions appear to reduce: sharing of needles/syringes compared to education/information (SMD −0.52; 95{\%} CI −1.02 to −0.03; I2 = 10{\%}; p = 0.04) or HIV testing/counselling (SMD −0.24; 95{\%} CI −0.44 to −0.03; I2 = 0{\%}; p = 0.02); sharing of other injecting paraphernalia (SMD −0.24; 95{\%} CI −0.42 to −0.06; I2 = 0{\%}; p < 0.01) and unprotected sex (SMD −0.44; 95{\%} CI −0.86 to −0.01; I2 = 79{\%}; p = 0.04) compared to interventions of a lesser time/intensity, however, moderate to high heterogeneity was reported. Such interventions could be included with other harm reduction approaches to prevent BBV transmission among PWID.",
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author = "Gail Gilchrist and Davina Swan and Kideshini Widyaratna and Marquez-Arrico, {Julia Elena} and Elizabeth Hughes and Mdege, {Noreen Dadirai} and {Martyn-St James}, Marrissa and Judit Tirado-Munoz",
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Gilchrist, G, Swan, D, Widyaratna, K, Marquez-Arrico, JE, Hughes, E, Mdege, ND, Martyn-St James, M & Tirado-Munoz, J 2017, 'A Systematic Review and Meta-analysis of Psychosocial Interventions to Reduce Drug and Sexual Blood Borne Virus Risk Behaviours Among People Who Inject Drugs', AIDS and Behavior, vol. 21, no. 7, pp. 1791-1811. https://doi.org/10.1007/s10461-017-1755-0

A Systematic Review and Meta-analysis of Psychosocial Interventions to Reduce Drug and Sexual Blood Borne Virus Risk Behaviours Among People Who Inject Drugs. / Gilchrist, Gail; Swan, Davina; Widyaratna, Kideshini; Marquez-Arrico, Julia Elena; Hughes, Elizabeth; Mdege, Noreen Dadirai; Martyn-St James, Marrissa; Tirado-Munoz, Judit.

In: AIDS and Behavior, Vol. 21, No. 7, 01.07.2017, p. 1791-1811.

Research output: Contribution to journalReview article

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AU - Marquez-Arrico, Julia Elena

AU - Hughes, Elizabeth

AU - Mdege, Noreen Dadirai

AU - Martyn-St James, Marrissa

AU - Tirado-Munoz, Judit

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