Allosteric and electrostatic reprogramming of a ditopic ligand

C.J. Baylies, L.P. Harding, J.C. Jeffery, T. Riis-Johannessen, C.R. Rice

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

A potentially tetradentate pyridyl–thiazole ligand chain and an additional “external” crown ether binding site connect the two halves of a new ditopic ligand. The pyridyl‐thiazole binding sites can be changed or “reprogrammed” by the addition of Ba2+: In the presence of Hg2+ and Na+ the ligand L1 forms a dinuclear double helicate ([Hg2(L1)2Na2]6+), whereas in the presence of Hg2+ and Ba2+ a mononuclear species is formed ([Hg(L1)Ba]4+).
LanguageEnglish
Pages4515-4518
Number of pages4
JournalAngewandte Chemie - International Edition
Volume43
Issue number34
DOIs
Publication statusPublished - 25 Aug 2004

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Thiazoles
Electrostatics
Ligands
Binding sites
Binding Sites
Crown Ethers
Crown ethers

Cite this

Baylies, C.J. ; Harding, L.P. ; Jeffery, J.C. ; Riis-Johannessen, T. ; Rice, C.R. / Allosteric and electrostatic reprogramming of a ditopic ligand. In: Angewandte Chemie - International Edition. 2004 ; Vol. 43, No. 34. pp. 4515-4518.
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Allosteric and electrostatic reprogramming of a ditopic ligand. / Baylies, C.J.; Harding, L.P.; Jeffery, J.C.; Riis-Johannessen, T.; Rice, C.R.

In: Angewandte Chemie - International Edition, Vol. 43, No. 34, 25.08.2004, p. 4515-4518.

Research output: Contribution to journalArticle

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