Allosteric and electrostatic reprogramming of a ditopic ligand

C.J. Baylies; L.P. Harding; J.C. Jeffery; T. Riis-Johannessen; C.R. Rice

doi:10.1002/anie.200460424

Allosteric and electrostatic reprogramming of a ditopic ligand

C.J. Baylies, L.P. Harding, J.C. Jeffery, T. Riis-Johannessen, C.R. Rice

University of Bristol

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

A potentially tetradentate pyridyl–thiazole ligand chain and an additional “external” crown ether binding site connect the two halves of a new ditopic ligand. The pyridyl‐thiazole binding sites can be changed or “reprogrammed” by the addition of Ba2+: In the presence of Hg2+ and Na+ the ligand L1 forms a dinuclear double helicate ([Hg2(L1)2Na2]6+), whereas in the presence of Hg2+ and Ba2+ a mononuclear species is formed ([Hg(L1)Ba]4+).

Original language	English
Pages (from-to)	4515-4518
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	43
Issue number	34
DOIs	https://doi.org/10.1002/anie.200460424
Publication status	Published - 25 Aug 2004

Access to Document

10.1002/anie.200460424Licence: Unspecified

https://www.scopus.com/inward/record.uri?eid=2-s2.0-4544234576&doi=10.1002%2fanie.200460424&partnerID=40&md5=db12916d646f8a1b1b86d037305d40aa

Cite this

@article{bc5a9a2ce2b143c580e40fe8f9f11867,

title = "Allosteric and electrostatic reprogramming of a ditopic ligand",

abstract = "A potentially tetradentate pyridyl–thiazole ligand chain and an additional “external” crown ether binding site connect the two halves of a new ditopic ligand. The pyridyl‐thiazole binding sites can be changed or “reprogrammed” by the addition of Ba2+: In the presence of Hg2+ and Na+ the ligand L1 forms a dinuclear double helicate ([Hg2(L1)2Na2]6+), whereas in the presence of Hg2+ and Ba2+ a mononuclear species is formed ([Hg(L1)Ba]4+).",

author = "C.J. Baylies and L.P. Harding and J.C. Jeffery and T. Riis-Johannessen and C.R. Rice",

note = "cited By 24",

year = "2004",

month = aug,

day = "25",

doi = "10.1002/anie.200460424",

language = "English",

volume = "43",

pages = "4515--4518",

journal = "Angewandte Chemie - International Edition",

issn = "1433-7851",

publisher = "John Wiley and Sons Ltd",

number = "34",

}

TY - JOUR

T1 - Allosteric and electrostatic reprogramming of a ditopic ligand

AU - Baylies, C.J.

AU - Harding, L.P.

AU - Jeffery, J.C.

AU - Riis-Johannessen, T.

AU - Rice, C.R.

N1 - cited By 24

PY - 2004/8/25

Y1 - 2004/8/25

N2 - A potentially tetradentate pyridyl–thiazole ligand chain and an additional “external” crown ether binding site connect the two halves of a new ditopic ligand. The pyridyl‐thiazole binding sites can be changed or “reprogrammed” by the addition of Ba2+: In the presence of Hg2+ and Na+ the ligand L1 forms a dinuclear double helicate ([Hg2(L1)2Na2]6+), whereas in the presence of Hg2+ and Ba2+ a mononuclear species is formed ([Hg(L1)Ba]4+).

AB - A potentially tetradentate pyridyl–thiazole ligand chain and an additional “external” crown ether binding site connect the two halves of a new ditopic ligand. The pyridyl‐thiazole binding sites can be changed or “reprogrammed” by the addition of Ba2+: In the presence of Hg2+ and Na+ the ligand L1 forms a dinuclear double helicate ([Hg2(L1)2Na2]6+), whereas in the presence of Hg2+ and Ba2+ a mononuclear species is formed ([Hg(L1)Ba]4+).

U2 - 10.1002/anie.200460424

DO - 10.1002/anie.200460424

M3 - Article

SN - 1433-7851

VL - 43

SP - 4515

EP - 4518

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 34

ER -

Allosteric and electrostatic reprogramming of a ditopic ligand

Abstract

Access to Document

Fingerprint

Cite this