1-Aryl-1-(2-bromophenyl)but-2-yn-1-ols, obtained from the addition of prop-1-yn-1-yllithium to 2-bromobenzophenones, readily rearrange to 4-aryl-4-(2-bromophenyl)but-3-en-2-ones upon treatment with TFA. Subsequent intramolecular Pd-mediated α-arylation of these but-3-en-2-ones gave 4-aryl-2-naphthols which were smoothly transformed into photochromic naphthopyrans. © 2015 Elsevier Ltd. All rights reserved.
|Publication status||Published - 12 Aug 2015|
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- Department of Chemical Sciences - Senior Lecturer in Chemistry
- School of Applied Sciences
- Centre for Functional Materials - Member
- Chemical Synthesis and Design Centre - Associate Member