An iron-catalysed C-C bond-forming spirocyclization cascade providing sustainable access to new 3D heterocyclic frameworks

Keyphrases

• Iron-catalyzed 100%
• Halo 100%
• C-C Bond Formation 100%
• Sustainable Access 100%
• Spirocyclization 100%
• Ether 50%
• Highly Stereoselective 50%
• Drug Substance 50%
• Cyclization 50%
• Structural Motif 50%
• Heterocycles 50%
• Carbon Atom 50%
• Aryloxy 50%
• Chiral Monomer 50%
• Cyclization Cascade 50%
• Bis-heterocycles 50%
• Fe(acac)3 50%
• Intermediate Metals 50%
• Asymmetric Center 50%
• Metal Species 50%
• Chemical Probes 50%
• Cascade Reaction 50%
• Iron Catalyst 50%
• Spirocycles 50%
• Catalytic Route 50%
• Aryl Ethers 50%
• Probe Drug 50%
• Spirocyclic 50%
• Plant Sources 50%
• Spatial Definition 50%
• Sp3 Carbon 50%
• Bioactive Natural Products 50%
• Arylamines 50%
• Grignard Reagents 50%

Chemistry

• Heterocyclic Compound 100%
• Spirocyclization 100%
• Monomer 20%
• Chemistry 20%
• Natural Product 20%
• Structural Motif 20%
• Carbon Atom 20%
• Grignard Reagent 20%
• Cascade Reaction 20%