Analysis of liquid-liquid droplets fission and encapsulation in single/two layer microfluidic devices fabricated by xurographic method

Chang Nong Lim, Kai Seng Koh, Yong Ren, Jit Kai Chin, Yong Shi, Yuying Yan

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

This paper demonstrates a low cost fabrication approach for microscale droplet fission and encapsulation. Using a modified xurography method, rapid yet reliable microfluidic devices with flexible designs (single layer and double layer) are developed to enable spatial control of droplet manipulation. In this paper, two different designs are demonstrated, i.e., droplet fission (single layer) and droplet encapsulation (double layer). In addition, the current fabrication approach reduces the overall production interval with the introduction of a custom-made polydimethylsiloxane (PDMS) aligner. Apart from that, the fabricated device is able to generate daughter droplets with the coefficient of variance (CV) below 5% and double emulsions with CV maintained within 10% without involvement of complex surface wettability modification.

LanguageEnglish
Article number49
JournalMicromachines
Volume8
Issue number2
DOIs
Publication statusPublished - 10 Feb 2017
Externally publishedYes

Fingerprint

Encapsulation
Microfluidics
Liquids
Fabrication
Polydimethylsiloxane
Emulsions
Wetting
Costs

Cite this

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title = "Analysis of liquid-liquid droplets fission and encapsulation in single/two layer microfluidic devices fabricated by xurographic method",
abstract = "This paper demonstrates a low cost fabrication approach for microscale droplet fission and encapsulation. Using a modified xurography method, rapid yet reliable microfluidic devices with flexible designs (single layer and double layer) are developed to enable spatial control of droplet manipulation. In this paper, two different designs are demonstrated, i.e., droplet fission (single layer) and droplet encapsulation (double layer). In addition, the current fabrication approach reduces the overall production interval with the introduction of a custom-made polydimethylsiloxane (PDMS) aligner. Apart from that, the fabricated device is able to generate daughter droplets with the coefficient of variance (CV) below 5{\%} and double emulsions with CV maintained within 10{\%} without involvement of complex surface wettability modification.",
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Analysis of liquid-liquid droplets fission and encapsulation in single/two layer microfluidic devices fabricated by xurographic method. / Lim, Chang Nong; Koh, Kai Seng; Ren, Yong; Chin, Jit Kai; Shi, Yong; Yan, Yuying.

In: Micromachines, Vol. 8, No. 2, 49, 10.02.2017.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Analysis of liquid-liquid droplets fission and encapsulation in single/two layer microfluidic devices fabricated by xurographic method

AU - Lim, Chang Nong

AU - Koh, Kai Seng

AU - Ren, Yong

AU - Chin, Jit Kai

AU - Shi, Yong

AU - Yan, Yuying

PY - 2017/2/10

Y1 - 2017/2/10

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AB - This paper demonstrates a low cost fabrication approach for microscale droplet fission and encapsulation. Using a modified xurography method, rapid yet reliable microfluidic devices with flexible designs (single layer and double layer) are developed to enable spatial control of droplet manipulation. In this paper, two different designs are demonstrated, i.e., droplet fission (single layer) and droplet encapsulation (double layer). In addition, the current fabrication approach reduces the overall production interval with the introduction of a custom-made polydimethylsiloxane (PDMS) aligner. Apart from that, the fabricated device is able to generate daughter droplets with the coefficient of variance (CV) below 5% and double emulsions with CV maintained within 10% without involvement of complex surface wettability modification.

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KW - Encapsulation

KW - Fission

KW - Microfabrication

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