Antibacterial activity of cold atmospheric pressure argon plasma against 78 genetically different (mecA, luk-P, agr or Capsular Polysaccharide Type) staphylococcus aureus strains

Rutger Matthes, Anne Lührman, Silva Holtfreter, Julia Kolata, Dörte Radke, Nils Olaf Hübner, Ojan Assadian, Axel Kramer

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Previous studies on the antimicrobial activity of cold atmospheric pressure argon plasma showed varying effects against mecA+ or mecA-Staphylococcus aureus strains. This observation may have important clinical and epidemiological implications. Here, the antibacterial activity of argon plasma was investigated against 78 genetically different S. aureus strains, stratified by mecA, luk-P, agr1-4, or the cell wall capsule polysaccharide types 5 and 8. kINPen09® served as the plasma source for all experiments. On agar plates, mecA+luk-P-S. aureus strains showed a decreased susceptibility against plasma compared to other S. aureus strains. This study underlines the high complexity of microbial defence against antimicrobial treatment and confirms a previously reported strain-dependent susceptibility of S. aureus to plasma treatment.

Original languageEnglish
Pages (from-to)83-91
Number of pages9
JournalSkin Pharmacology and Physiology
Volume29
Issue number2
DOIs
Publication statusPublished - 1 May 2016

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Atmospheric Pressure
Argon
Polysaccharides
Staphylococcus aureus
Cell Wall
Agar
Capsules

Cite this

Matthes, Rutger ; Lührman, Anne ; Holtfreter, Silva ; Kolata, Julia ; Radke, Dörte ; Hübner, Nils Olaf ; Assadian, Ojan ; Kramer, Axel. / Antibacterial activity of cold atmospheric pressure argon plasma against 78 genetically different (mecA, luk-P, agr or Capsular Polysaccharide Type) staphylococcus aureus strains. In: Skin Pharmacology and Physiology. 2016 ; Vol. 29, No. 2. pp. 83-91.
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Antibacterial activity of cold atmospheric pressure argon plasma against 78 genetically different (mecA, luk-P, agr or Capsular Polysaccharide Type) staphylococcus aureus strains. / Matthes, Rutger; Lührman, Anne; Holtfreter, Silva; Kolata, Julia; Radke, Dörte; Hübner, Nils Olaf; Assadian, Ojan; Kramer, Axel.

In: Skin Pharmacology and Physiology, Vol. 29, No. 2, 01.05.2016, p. 83-91.

Research output: Contribution to journalArticle

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