Antinociceptive effect of Russelia equisetiformis leave extracts: Identification of its active constituents

E. O. Awe; A. Adeloye; T. Idowu; O. A. Olajide; J. Makinde

doi:10.1016/j.phymed.2007.03.012

Antinociceptive effect of Russelia equisetiformis leave extracts: Identification of its active constituents

E. O. Awe, A. Adeloye, T. Idowu, O. A. Olajide, J. Makinde

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

This study examines the antinociceptive effect of the whole plant extracts of Russelia equisetiformis. The result shows the ethylacetate fraction to be the most active, while the dichloromethane fraction exhibited least activity. The major isolated compound from the ethylacetate showed a tremendous activity on acetic acid induced writhing with less activity on tail-flick response in mice. The structures of the two compounds were assigned on the basis of spectroscopic data. Occurrence of these compounds in Russelia is reported here for the first time, and the results confirm the traditional uses of R. equisetiformis in the treatment of inflammation and pain.

Original language	English
Pages (from-to)	301-305
Number of pages	5
Journal	Phytomedicine
Volume	15
Issue number	4
DOIs	https://doi.org/10.1016/j.phymed.2007.03.012
Publication status	Published - 25 Apr 2008
Externally published	Yes

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10.1016/j.phymed.2007.03.012

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title = "Antinociceptive effect of Russelia equisetiformis leave extracts: Identification of its active constituents",

abstract = "This study examines the antinociceptive effect of the whole plant extracts of Russelia equisetiformis. The result shows the ethylacetate fraction to be the most active, while the dichloromethane fraction exhibited least activity. The major isolated compound from the ethylacetate showed a tremendous activity on acetic acid induced writhing with less activity on tail-flick response in mice. The structures of the two compounds were assigned on the basis of spectroscopic data. Occurrence of these compounds in Russelia is reported here for the first time, and the results confirm the traditional uses of R. equisetiformis in the treatment of inflammation and pain.",

keywords = "2-(3, 4-dihydroxyphenyl)-ethyl-)5-O-caffeoyl)-β-d-rhamnopyranside, Antinociceptive activity, Phenylethanoid glycoside, Russelia equisetiformis, Scrophulariacae",

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T2 - Identification of its active constituents

AU - Awe, E. O.

AU - Adeloye, A.

AU - Idowu, T.

AU - Olajide, O. A.

AU - Makinde, J.

PY - 2008/4/25

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AB - This study examines the antinociceptive effect of the whole plant extracts of Russelia equisetiformis. The result shows the ethylacetate fraction to be the most active, while the dichloromethane fraction exhibited least activity. The major isolated compound from the ethylacetate showed a tremendous activity on acetic acid induced writhing with less activity on tail-flick response in mice. The structures of the two compounds were assigned on the basis of spectroscopic data. Occurrence of these compounds in Russelia is reported here for the first time, and the results confirm the traditional uses of R. equisetiformis in the treatment of inflammation and pain.

KW - 2-(3, 4-dihydroxyphenyl)-ethyl-)5-O-caffeoyl)-β-d-rhamnopyranside

KW - Antinociceptive activity

KW - Phenylethanoid glycoside

KW - Russelia equisetiformis

KW - Scrophulariacae

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JO - Phytomedicine

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ER -

Antinociceptive effect of Russelia equisetiformis leave extracts: Identification of its active constituents

Abstract

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