In this paper, we present a new method for the design of multi-band microstrip filters. The proposed design method is based on Differential Evolution (DE) with strategy adaptation. This self-adaptive DE (SaDE) uses previous experience in both trial vector generation strategies and control parameter tuning. We apply this algorithm to two design cases of dual and tri-band filters for WiFi and WiMax applications. We select the Open Loop Ring Resonator (OLRR) filters, which are comprised of two uniform microstrip lines and pairs of open loops between them. The results indicate the advantages of this approach and the applicability of this design method.