Beta-blocker use in cardiovascular disease

Amie Bain

Research output: Contribution to journalArticlepeer-review


Beta-blockers are widely used to treat a number of cardiovascular
diseases, including heart failure, myocardial infarction, atrial fibrillation,
angina and hypertension. By inhibiting the binding of catacholamines to
beta receptors in the heart and vasculature, beta-blockers can reduce
cardiac contractility, heart rate, blood pressure and cardiac output. A
sound understanding of how beta-blockers work and the basis of their
recommendation for various indications is needed to promote their
safe and effective use in patients. This article briefly describes the
physiology of beta-adrenergic receptors, the mechanism of action of
beta-blockers and their place in the therapy of cardiovascular disease.
Original languageEnglish
Pages (from-to)491-497
Number of pages7
JournalBritish Journal of Cardiac Nursing
Issue number10
Publication statusPublished - 4 Oct 2018


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