Beta-blocker use in cardiovascular disease

Research output: Contribution to journalArticle

Abstract

Beta-blockers are widely used to treat a number of cardiovascular
diseases, including heart failure, myocardial infarction, atrial fibrillation,
angina and hypertension. By inhibiting the binding of catacholamines to
beta receptors in the heart and vasculature, beta-blockers can reduce
cardiac contractility, heart rate, blood pressure and cardiac output. A
sound understanding of how beta-blockers work and the basis of their
recommendation for various indications is needed to promote their
safe and effective use in patients. This article briefly describes the
physiology of beta-adrenergic receptors, the mechanism of action of
beta-blockers and their place in the therapy of cardiovascular disease.
Original languageEnglish
Pages (from-to)491-497
Number of pages7
JournalBritish Journal of Cardiac Nursing
Volume13
Issue number10
DOIs
Publication statusPublished - 4 Oct 2018

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Receptors, Adrenergic, beta
Cardiac Output
Atrial Fibrillation
Cardiovascular Diseases
Heart Failure
Heart Rate
Myocardial Infarction
Blood Pressure
Hypertension
Therapeutics

Cite this

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title = "Beta-blocker use in cardiovascular disease",
abstract = "Beta-blockers are widely used to treat a number of cardiovasculardiseases, including heart failure, myocardial infarction, atrial fibrillation,angina and hypertension. By inhibiting the binding of catacholamines tobeta receptors in the heart and vasculature, beta-blockers can reducecardiac contractility, heart rate, blood pressure and cardiac output. Asound understanding of how beta-blockers work and the basis of theirrecommendation for various indications is needed to promote theirsafe and effective use in patients. This article briefly describes thephysiology of beta-adrenergic receptors, the mechanism of action ofbeta-blockers and their place in the therapy of cardiovascular disease.",
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Beta-blocker use in cardiovascular disease. / Bain, Amie.

In: British Journal of Cardiac Nursing, Vol. 13, No. 10, 04.10.2018, p. 491-497.

Research output: Contribution to journalArticle

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KW - Pharmacology

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KW - Angina

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