Abstract
Beta-blockers are widely used to treat a number of cardiovascular
diseases, including heart failure, myocardial infarction, atrial fibrillation,
angina and hypertension. By inhibiting the binding of catacholamines to
beta receptors in the heart and vasculature, beta-blockers can reduce
cardiac contractility, heart rate, blood pressure and cardiac output. A
sound understanding of how beta-blockers work and the basis of their
recommendation for various indications is needed to promote their
safe and effective use in patients. This article briefly describes the
physiology of beta-adrenergic receptors, the mechanism of action of
beta-blockers and their place in the therapy of cardiovascular disease.
diseases, including heart failure, myocardial infarction, atrial fibrillation,
angina and hypertension. By inhibiting the binding of catacholamines to
beta receptors in the heart and vasculature, beta-blockers can reduce
cardiac contractility, heart rate, blood pressure and cardiac output. A
sound understanding of how beta-blockers work and the basis of their
recommendation for various indications is needed to promote their
safe and effective use in patients. This article briefly describes the
physiology of beta-adrenergic receptors, the mechanism of action of
beta-blockers and their place in the therapy of cardiovascular disease.
Original language | English |
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Pages (from-to) | 491-497 |
Number of pages | 7 |
Journal | British Journal of Cardiac Nursing |
Volume | 13 |
Issue number | 10 |
DOIs | |
Publication status | Published - 4 Oct 2018 |